Genetic disorders have been the focus of scientists for a long time. The emergence of next-generation sequencing techniques has ushered a new era in genetics and several developments have occurred in human genetics. The scientific perspective has also been widened with omics technologies that allow researchers to analyze genetic sequences and their expression products. An integrated approach is being used not only for diagnosis but also for disease management and therapeutic purposes. This book highlights emerging areas of omics technology and its application in the diagnosis and management of human genetic disorders. The book covers three areas of research and implementation: - Diagnosis (covering conventional strategies to next-generation platforms). This section focuses on the role of in silico analysis, databases and multi-omics of single-cell which will help in designing better management strategies. - Disease Management and therapeutic interventions. This section starts with genetic counselling and progresses to more specific techniques such as pharmacogenomics and personalized medicine, gene editing techniques and their applications in gene therapies and regenerative medicine. - Case studies. This section discusses the applications and success of all the above-mentioned strategies on selected human disorders. This book serves as a handy reference for students and academics studying advanced omics techniques in biochemistry and molecular genetics as part of courses in life sciences, pharmacology and medicine.

Bio-based polymers are materials that are produced from renewable resources. Their biodegradable properties are the driver of worldwide interest among researchers and manufacturers in recent years due to the demand and need for alternatives to fossil fuel based polymers. The use of biodegradable polymers creates a sustainable industry. In contrast, the raw materials for synthetic polymers derived from petrochemicals will eventually deplete and most of them are non-biodegradable. Despite these advantages, bio-based polymers account for only a tiny fraction of the total global plastic market. Non-biodegradability issues of synthetic pharmaceutical inactive ingredients strongly emphasized innovators towards the development of biopolymers. Recently natural biodegradable excipients gained significant attention due to their sustainability and engineered applications. Innovative technologies to transform these materials into value-added chemicals via novel graft-polymerization or co-processing techniques for the production of high-performance multifunctional and low-cost polymers with tunable structures are key parts of its sustainable development. Biopolymers Towards Green and Sustainable Development elaborates on important issues that surround bio-based polymers. It gives the reader an overview of biopolymers, the impact of non-biodegradable polymers on the environment and health, emerging sources of biodegradable polymers, structural and morphological characterization techniques, thermomechanical properties, biodegradable plastics from biopolymers, pharmaceutical, biomedical, and textile applications, and pharmacokinetics and pharmacodynamics. with a brief on bibliometric. Moreover, a brief bibliometric meta-analysis on bio-based pharmaceutical excipients provides an update about teams involved in the development of polymeric research that may be of interest to anyone who wants to work on sustainable biopolymer projects. Key Features - provides an updated summary on recently discovered natural polymeric materials - gives a thorough breakdown of the vast range of biopolymer applications including fabrication of conventional and novel drug delivery, polymeric scaffolds, composites, microneedles, and green synthesis of metallic nanoparticles, -summarizes pharmacology and pharmacokinetics of the inactive pharmaceutical ingredient and excipients - presents a bibliometric meta-analysis indicating potential collaboration between country, organization, institution, and authors with a view on recent ongoing trends with biopolymers.

Terpenoids are commercially important chemicals found in essential oils and other natural plant sources. They are used in solving issues that affect agricultural production, making them a key component of sustainable agronomy. Terpenoids: Recent Advances in Extraction, Biochemistry and Biotechnology provides information about the varied use of terpenoids in the control of pests, microbial diseases, ticks, and weeds. Chapters have prioritized terpenoids produced by plants, endophytic fungi, propolis, and geopropolis. The book also provides focused information about the functions of terpenoids in plants, as well as their biosynthetic pathways of production. The reference provides readers with a broad and diverse picture of the applications of terpenoids in plant safety, and creates an awareness of the possibilities for innovative biotechnological approaches for their extraction that make all the difference to agricultural production. Professionals and scholars involved in chemical technology, biotechnology and agriculture will benefit from the information provided in the book. It also serves as a comprehensive update for general readers interested in terpenoids and their current impact on the agricultural industry.

Environmental Microbiology: Advanced Research and Multidisciplinary Applications focus on the current research on microorganisms in the environment. Contributions in the volume cover several aspects of applied microbial research, basic research on microbial ecology and molecular genetics. The reader will find a collection of topics with theoretical and practical value, allowing them to connect environmental microbiology to a variety of subjects in life sciences, ecology, and environmental science topics. Advanced topics including biogeochemical cycling, microbial biosensors, bioremediation, application of microbial biofilms in bioremediation, application of microbial surfactants, microbes for mining and metallurgical operations, valorization of waste, and biodegradation of aromatic waste, microbial communication, nutrient cycling and biotransformation are also covered. The content is designed for advanced undergraduate students, graduate students, and environmental professionals, with a comprehensive and up-to-date discussion of environmental microbiology as a discipline that has greatly expanded in scope and interest over the past several decades.

Biomarkers in Medicine is a comprehensive guide to understanding the current and future status of biomarkers. The book features 27 chapters focusing on disease biomarkers for diseases such as cancer, neurodegenerative diseases, cardiac diseases, metabolic conditions and much more. This book supplies readers with the unique insight of experts in multiple specialties in medicine and life sciences who have extensive experience in diagnostics and clinical laboratories. The book includes case studies and practical examples from different classes of biomarkers on different platforms, including new data for biomarkers in different therapeutic indications. In addition to presenting biomarker information, each chapter covers the relevant pathology and also emphasizes on preclinical and clinical manifestation of the disease process. Clinicians managing patients or clinical trials, clinical researchers, clinical laboratories, diagnostic companies, regulatory agencies, medical school graduate students, academic students, and the general public involved in healthcare delivery will all benefit from information presented in this book.

This volume is a compilation of reviews on the industrial usage of soil microorganisms. The contents include 15 brief reviews on different soil microbe assisted industrial processes. Readers will be updated about recent applications of soil bacteria, fungi and algae in sectors such as agriculture, biotechnology, environmental management. The reviews also cover special topics like sustainable agriculture, biodiversity, ecology, and intellectual property rights of patented strains, giving a broad perspective on industrial applications of soil microbes. The text is easy to understand for readers of all levels, with references provided for the benefit of advanced readers.

More than 4 decades have passed since the birth of the first in vitro fertilized baby in 1978. The use of assisted reproductive technology (ART) to overcome infertility has increased steadily with the simultaneous increase in the number of fertility centers in every part of the world. Access to infertility clinics is playing an important role in the treatment of different forms of infertility (like tubal disease, ovarian aging, or ovarian dysfunction). This book captures the state of current and recent advances in assisted reproduction technology in humans and livestock in an easy and comprehensive way for non-experts and learners. 10 chapters cover the biology of reproduction, and male ART methods (sperm retrieval and freezing) and female ART methods (oocyte activation, and cryopreservation), and finally embryo ARTs (assisted hatching and cloning techniques) with simple definitions and explanations. Tips to overcome problems are also presented where appropriate along with references for further reading. This book is a simple primer for students who are involved in courses in embryology or reproductive technologies as part of programs in biology, biotechnology, medicine, and physiology.

Sustainable Utilization of Fungi in Agriculture and Industry covers current knowledge about of different fungal microorganisms, including economically important filamentous fungi and yeasts. 22 chapters summarize recent information about scientific investigations and the application of fungi in the production of industrial enzymes, organic acids (citric acid, lactic acid, etc.), biofuel (ethanol, H2 gas) and bioactive compounds for sustainable processes in agriculture, bioremediation, industries and therapeutics. Each chapter gives an updated and detailed account of knowledge on fungal microbes and their sustainable utilization in agriculture, white biotechnology, and other valuable industrial applications. Contributions are made by academic and professional experts in mycology and industrial biotechnology, presenting a broad perspective of the field in a simple, yet engaging style. Sustainable Utilization of Fungi in Agriculture and Industry is an informative reference for general readers, trainees, interested in sustainability measures in agriculture and industry. It also serves as reading materials for scholars, students and teachers involved in botany, microbiology, biotechnology and life sciences courses.

Myconanotechnology is the interface between mycology and nanotechnology. In other words, myconanotechnology represents the green synthesis of nanoparticles using fungi. The field is recently gaining attention due to the simple, resource efficient, and ecofriendly nature of fungal biotechnology. Therefore, Myconanotechnology is at the core of cost-effective and sustainable solutions for many industrial processes. This volume provides readers at all academic levels with a broad background on some of the fastest developing areas in myconanotechnology. It is organised into two sections, A and B. Section A updates readers on several cutting-edge aspects of the synthesis and characterization of nanoparticles through the use of fungi. Section B describes applications of myconanotechnology including: the management of bacterial and fungal diseases, pest control, among other applications in medicine and agriculture. The breadth of topics covered in the contents make this volume an informative resource on the field. Contributions are written by experts in industrial biotechnology, and include extensive references to published studies. This book is a timely reference for researchers, teachers and students, and all readers who are interested in new developments in industrial mycology and nanotechnology.

Bioluminescence, the cold living light or the cold fire of the sea is extremely common in all oceans at all depths. However, this phenomenon is nearly absent in freshwater, with the exception of a freshwater limpet. More than 75% of deep-sea creatures have been reported to produce their own light. The luminescent marine plankton such as dinoflagellate, radiolarians, jellyfish, comb jellies, annelids, copepods, ostracods, mysids, amphipods, euphausiids, and tunicates form an important component in the marine food chain. Research on luminescent marine plankton is gaining momentum owing to its importance in life science research and medicine. The glowing Green Fluorescent Protein (GFP) extracted from the North Pacific jellyfish, Aqueorea victoria (for which the Japanese biologist, Osamu Shimonmura won the Nobel Prize in Chemistry in 2008) has helped shed light on key processes such as the spread of cancer, the development of brain cells, the growth of bacteria, damage to cells by Alzheimer's disease, and the development of insulin-producing cells in the pancreas. Therefore, it is difficult to underscore the importance of bioluminescence and the organisms associated with this phenomenon. Bioluminescent Marine Plankton is a unique reference that attempts to provide answers to questions about bioluminescence. The first of its kind, this book attempts to answer questions on the subject with a focus on planktonic organisms. 12 chapters provide information about the chemistry of bioluminescence, types of bioluminescent displays, distribution of bioluminescence among marine plankton, ecological functions and utility of planktonic bioluminescence. Chapters are dedicated to the biology and ecology of specific groups of plankton that span about 200 luminescent marine species. The detailed book is an essential compendium on marine plankton for a broad range of readers who want to learn about bioluminescent plankton. A list of detailed references is also provided for the benefit of teachers, students, researchers and enthusiasts interested in marine biology, aquaculture, and environmental sciences.