Genetic Explorations of Pain

Abstract

Pain is the most prevalent form of human health malady which, if remain unaddressed, exerts formidable impact. Pain research has tried hard to unravel the possibilities in the direction of diagnosis and management of pain conditions, but knowledge of genetic consequences of pain is still in infancy. During pain, sensory input is realized, processed and regulated, first and foremost through ones genetic composition and then different characters of physiology, psychology, sociology and environment come in the scene. The present exposition demonstrates the precise details of various genes and genetic variants that participate in different phases of pain and pain conditions, disseminating an idea that in future, diagnosis and treatment of pain by harnessing indepth genetic knowledge has startling revelations in store for us.

Keywords: Chronic pain, Conduction, Genes, Modulation, Synaptic transmission, Transduction.

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