Abstract
Epigenetic modifications (EMs) refer to the external modifications on DNA that do not alter coding specificity. EMs include DNA methylations (DMs) and histone modifications (HMs). This chapter will focus on HMs. We will discuss how ChIP-EM libraries can be made and what can be expected from the sequence data analysis. There are many laboratories working in this field and many reports have been published. Readers are recommended to consult the previous reports for further understanding of this subject.
Keywords: Chromatin immunoprecipitation, ChIP, EM, Epigenetic modifications.
About this chapter
Cite this chapter as:
Kuo Ping Chiu ;ChIP-EM Libraries, Next-Generation Sequencing and Sequence Data Analysis (2015) 1: 112. https://doi.org/10.2174/9781681080925115010017
DOI https://doi.org/10.2174/9781681080925115010017 |
Publisher Name Bentham Science Publisher |