Recent Bio-Based Material Strategies to Regenerate Periodontal Tissue in Clinical Setting

Periodontitis draws much attention because of its escalating burden on the healthcare economy in both developed and developing countries. For decades, periodontitis has been acknowledged as the most common oral disease worldwide and mostly found in the productive age. The inflammation in periodontal tissue destructs periodontal complex structures: periodontal ligament, cementum, and alveolar bone. Hence, its therapy is directed to interrupt disease progression and restore damaged tissue. The regenerative approach has been recognized by the periodontal association, and it has been integrated in their clinical practice guidelines for treating periodontitis. Various regenerative therapies have been introduced to dental clinics, which provide a wide range of treatment services. The regenerative approach is selected based on the consideration involving the interest of patients and clinicians. However, in its development, regulatory, public, and manufacturer concerns must also be taken into account. This paper exclusively discusses bio-functional materials used in dental clinics to regenerate periodontal defects. The brief evaluation describes recent periodontal regenerative materials available in clinics and clinician’s expectations of future therapies. 

Keywords: Guided-tissue regeneration, Membrane barrier, Periodontitis, Periodontal regeneration.