In silico Interactions of the Biomolecules of Edible Mushrooms Against Lifestyle Diseases

Mushrooms are fungi that are consumed all over the world and contain bioactive nutritive components with nutritional and therapeutic qualities. Protein, minerals, vitamins and antioxidants are all found in edible mushrooms. Selenium, vitamin C, and choline are antioxidants that help the human body remove free radicals. Antimicrobial, antiviral, anticancer, anti-allergic, immunomodulation, anti-inflammatory, anti-atherogenic, hypoglycemic, hepatoprotective, and antioxidant properties of mushrooms. Primary and secondary metabolites can be found in mushrooms. The primary metabolites are energy-producing, but the secondary metabolites have therapeutic qualities. As the bioactive molecule has a pharmacological effect, researchers have recently focused on extracting it. As a result, the mushroom has the potential to be a recipe for human health and play a key role in the battle against COVID-19 pandemics and other infectious illnesses. Mushrooms and their biomolecules have therapeutic properties in a variety of diseases, including cardiovascular, diabetes, reproductive problems, cancer, and neurological disorders. A computer method, or in silico technology, is promising early evidence for drug development. Molecular docking studies have discovered bioactive chemicals from natural items like mushrooms as possible inhibitors against various diseases.

Keywords: Biomolecules, Diseases, In silico, Mushroom