The Amazing World of Peptide Engineering: the Example of Antimicrobial Peptides from Frogs and Their Analogues

Aline   B.   Guimarães; Fabiano   J.Q.   Costa; Osmindo   R.P.   Júnior; Wagner      Fontes; Mariana   S.   Castro

doi:10.2174/0929866523666160530185137

Abstract

This review discusses the importance and properties of antimicrobial peptides from frogs and their synthetic analogues as potential therapeutic alternatives in fighting not only bacterial infections, but also protozoans involved with the major neglected diseases, which afflict human populations (e.g., Chagas disease, African sleeping sickness, Leishmaniasis and malaria). Here, we emphasize their multifunctional properties such as promising broad-spectrum drugs that target protozoan parasites too.

Keywords: Anurans, antimicrobial peptides, analogues, protozoa.

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Protein & Peptide Letters

Title:The Amazing World of Peptide Engineering: the Example of Antimicrobial Peptides from Frogs and Their Analogues

Volume: 23 Issue: 8

Author(s): Aline B. Guimarães, Fabiano J.Q. Costa, Osmindo R.P. Júnior, Wagner Fontes and Mariana S. Castro

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Keywords: Anurans, antimicrobial peptides, analogues, protozoa.

Abstract: This review discusses the importance and properties of antimicrobial peptides from frogs and their synthetic analogues as potential therapeutic alternatives in fighting not only bacterial infections, but also protozoans involved with the major neglected diseases, which afflict human populations (e.g., Chagas disease, African sleeping sickness, Leishmaniasis and malaria). Here, we emphasize their multifunctional properties such as promising broad-spectrum drugs that target protozoan parasites too.

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Cite this article as:

Guimarães B. Aline, Costa J.Q. Fabiano, Júnior R.P. Osmindo, Fontes Wagner and Castro S. Mariana, The Amazing World of Peptide Engineering: the Example of Antimicrobial Peptides from Frogs and Their Analogues, Protein & Peptide Letters 2016; 23 (8) . https://dx.doi.org/10.2174/0929866523666160530185137

DOI https://dx.doi.org/10.2174/0929866523666160530185137	Print ISSN 0929-8665
Publisher Name Bentham Science Publisher	Online ISSN 1875-5305

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