Abstract
Quercetin, a widely occurring plant flavonoid, is well-known for its antioxidant activity. A great deal of research in the form of animal and cell culture studies has been performed over the last 30 years, as well as a few clinical studies in human populations; however, its specific effects on various contributing factors to cardiovascular disease are not fully understood. This review seeks to summarize many of the latest studies regarding the effects of quercetin on cardiovascular health. Overall, the research reflects positive effects of quercetin on atherosclerosis, hypertension, dyslipidemia and endothelial function. However, in vivo studies have shown that quercetin imparts varying plasma levels due to its poor aqueous solubility and low stability in biological fluids. Research efforts are currently being devoted to overcome these limitations by designing and testing modified forms of quercetin or improved formulations which provide enhanced bioavailability and higher efficacy. The development of improved dosage forms for in vivo administration of quercetin and well-designed clinical studies are warranted for further evaluation of the effects of quercetin on cardiovascular health.
Keywords: Antioxidants, atherosclerosis, cardiovascular disease, dyslipidemia, endothelial function, oxidative stress, plant flavonoid, quercetin, formulations.
Call for Papers in Thematic Issues
Bioactive compounds, functional foods, metabolism, and health
Nutrition, metabolism, and their intervention strategies have become focal points of interest in the study of metabolic syndrome and health. Bioactive compounds, phytochemicals, and functional foods play crucial roles in modulating metabolic processes and improving human health. Moreover, the composition of the gut microbiome is also believed to be closely ...read more
The Core Linkage Between Probiotics Encapsulation by the Natural Phytochemicals as Health and nutritional-related Functional Products: Recent Applications
The exploration of probiotics encapsulation through natural phytochemicals has emerged as a pivotal area of research, particularly in the context of health and nutrition. Probiotics, defined as live microorganisms that confer health benefits to the host, have gained considerable attention for their role in enhancing gut health, boosting the immune ...read more
Related Books
Vitamin D - A Novel Therapy for Chronic Diseases?
Bio-Based Antimicrobial Agents to Improve Agricultural and Food Safety
Functional Foods for Health Maintenance: Understanding their Role in Cancer Prevention
Green Extraction Techniques in Food Analysis
Algal Functional Foods and Nutraceuticals: Benefits, Opportunities, and Challenges
Micronutrients: The Key to Good Health
Capillary Electrophoresis in Food Analysis
Nutritional Biochemistry: From the Classroom to the Research Bench
Hypersensitivity to Vitamins
Foods for Special Dietary Regimens
51
