Abstract
Protein glycosylation represents one of the most important post-translational events, and is a mean of diversifying a protein without recourse to the genome. The venoms produced by snakes contain an abundance of glycoproteins with N-linked carbohydrates. N-linked glycosylation can ensure the correct folding of important functional domains. Characterization of carbohydrates structures aids in development of human therapeutics by snake venom toxins.
Keywords: N-linked oligosaccharides, snake venom, enzyme activity, serine protease
Protein & Peptide Letters
Title: Venom-Sweet-Venom: N-Linked Glycosylation in Snake Venom Toxins
Volume: 16 Issue: 8
Author(s): Sandro G. Soares and Leandro L. Oliveira
Affiliation:
Keywords: N-linked oligosaccharides, snake venom, enzyme activity, serine protease
Abstract: Protein glycosylation represents one of the most important post-translational events, and is a mean of diversifying a protein without recourse to the genome. The venoms produced by snakes contain an abundance of glycoproteins with N-linked carbohydrates. N-linked glycosylation can ensure the correct folding of important functional domains. Characterization of carbohydrates structures aids in development of human therapeutics by snake venom toxins.
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Cite this article as:
Soares G. Sandro and Oliveira L. Leandro, Venom-Sweet-Venom: N-Linked Glycosylation in Snake Venom Toxins, Protein & Peptide Letters 2009; 16 (8) . https://dx.doi.org/10.2174/092986609788923293
DOI https://dx.doi.org/10.2174/092986609788923293 |
Print ISSN 0929-8665 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5305 |
Call for Papers in Thematic Issues
Therapeutic Proteins and Peptides of Plant Origin
Plants are still the major repository of biologically active substances. In the last two decades, however, natural peptides and proteins of plant origin have gained increasing attention due to their pharmacological activities over a variety of human illnesses, including those mediated by infections and parasitosis and those involving different cellular ...read more
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