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Current Bioactive Compounds

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ISSN (Online): 1875-6646

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Mini-Review Article

The Voyage of Natural Chalcone: Isoliquiritigenin

Author(s): Himanshu Rani*

Volume 20, Issue 1, 2024

Published on: 15 August, 2023

Article ID: e170523217028 Pages: 20

DOI: 10.2174/1573407219666230517154830

Price: $65

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Abstract

This review aims to provide a comprehensive summary of the pharmacological effects of isoliquiritigenin, a natural chalcone. The data was gathered from a variety of research papers published till 2022. The extensive pharmacological features of ISL, including its anti-inflammatory, anti-influenza, anti-tyrosinase, anti-bacterial, anti-sarcoma, anti-oxidative, anti-leiomyoma, anticholera, anti-asthma, anti-diabetic, and anti-cancer activity, neuroprotective, hepatoprotective, and cardioprotective effects, may explain its practical applicability in the treatment and prevention of many illnesses. However, to confirm the target-organ toxicity or side effects, more research is required. The creation and design of new ISL analogues based on previously discovered techniques may benefit from this review.

Keywords: Isoliquiritigenin, chalcone, anti-influenza, anti-tyrosinase, anti-bacterial, anti-sarcoma, anti-oxidative, anti-leiomyoma, anti-cholera.

Graphical Abstract

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