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Current Traditional Medicine

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ISSN (Print): 2215-0838
ISSN (Online): 2215-0846

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Research Article

Ethnomedicinal and Ethnobotanical Investigations and Documentation of Plants Used by Traditional Healers of Eastern India

Author(s): Melaku Masresha Woldeamanel, Soumyaranjan Senapati, Shibani Mohapatra, Hatanath Subudhi, Prasanta Rath and Alok Kumar Panda*

Volume 8, Issue 6, 2022

Published on: 22 July, 2022

Article ID: e100522204524 Pages: 26

DOI: 10.2174/2215083808666220510115510

Price: $65

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Abstract

Introduction: This study is an effort to document extensively and systematically the ethnobotanical and ethnomedicinal knowledge in the four districts (Puri, Cuttack, Bhadrak, and Mayurbhanj) of Odisha in Eastern India. It provides new insights into the rich ethnomedicinal knowledge and plants biodiversity in these four districts.

Methods: The method of convenience sampling was conducted to get the ethnobotanical and ethnomedicinal knowledge of the healers. Semi-structured interviews were conducted, and the information got was quantified and documented with the aid of various databases. Eleven traditional healers endowed information on their traditional medicinal knowledge. 74 plant species belonging to 44 botanical families are documented and among these 44 botanical families, five (Rutaceae, Malvaceae, Astaraceae, Annonaceae, and Euphorbiaceae) are mostly used by the healers. The healers mainly use leaves and roots in the medicine's preparation.

Results: Twenty-five ailments are treated by these traditional healers, which are majorly dominated by dermatological treatments. The pharmacological mining of these 74 plants revealed that a few pharmacological and biological activities of each medicinal plant had been studied. Our study revealed that these four districts of Odisha have a rich biodiversity of medicinal plants.

Conclusion: Promoting the plantation of some of these species can enhance the income of the traditional healers of these districts and simultaneously make the exploitation of these plant species sustainable. We also found that the pharmacological and biological activities of many plant species are yet to be explored.

Keywords: Ethnobotanical, ethnomedicinal, traditional healers, pharmacological activities, biological activities, rutaceae, malvaceae, astaraceae.

Graphical Abstract

[1]
Yuan H, Ma Q, Ye L, Piao G. The traditional medicine and modern medicine from natural products. Molecules 2016; 21(5): 559.
[http://dx.doi.org/10.3390/molecules21050559] [PMID: 27136524]
[2]
Wangchuk P, Yeshi K, Jamphel K. Pharmacological, ethnopharmacological, and botanical evaluation of subtropical medicinal plants of Lower Kheng region in Bhutan. Integr Med Res 2017; 6(4): 372-87.
[http://dx.doi.org/10.1016/j.imr.2017.08.002] [PMID: 29296564]
[3]
Rath S, Ormsby AA. Conservation through traditional knowledge: A review of research on the sacred groves of Odisha, India. Hum Ecol Interdiscip J 2020; 48(4): 455-63.
[http://dx.doi.org/10.1007/s10745-020-00173-1]
[4]
Pradhan A, Ormsby AA, Behera N. A comparative assessment of tree diversity, biomass and biomass carbon stock between a protected area and a sacred forest of Western Odisha, India. Ecoscience 2019; 26(3): 195-204.
[http://dx.doi.org/10.1080/11956860.2019.1586118]
[5]
Contractor SQ, Das A, Dasgupta J, Van Belle S. Beyond the template: The needs of tribal women and their experiences with maternity services in Odisha, India. Int J Equity Health 2018; 17(1): 134.
[http://dx.doi.org/10.1186/s12939-018-0850-9] [PMID: 30244683]
[6]
Ningaiah N, Gangadhar M. Indigenous knowledge on medicinal plants among the iruliga tribal population of Western Ghats areas, Karna-taka, India. Antrocom J Anthropol 2013; 9(1): 195-203.
[7]
Bandita KD, Sagarika P, Bhattacharyay D, Mahalik G. Diversified hydrophytes in different aquatic habitats of puri district, Odisha, India. Adv Zoo Botany 2019; 7(3): 53-60.
[8]
Sanjeet Kumar GD, Han-Seung S, Kumar P. Diversity of plant species in the steel city of Odisha, India: Ethnobotany and implications for conservation of urban bio-resources. Braz Arch Biol Technol 2018; 61: 19.
[9]
Behera K, Mandal U, Panda M, et al. Ethnobotany and folk medicines used by the local healers of bhadrak, Odisha, India. Egypt J Bot 2021; 61(2): 375-89.
[10]
SKaKL Barik. Eco-floristic studies on sacred groves of bamanghaty subdivision in mayurbhanj district, Odisha and its conservation strat-egies. Indian J Res 2015; 4(6): 2.
[11]
Ngarivhume T, Van’t Klooster CI, de Jong JT, Van der Westhuizen JH. Medicinal plants used by traditional healers for the treatment of malaria in the Chipinge district in Zimbabwe. J Ethnopharmacol 2015; 159: 224-37.
[http://dx.doi.org/10.1016/j.jep.2014.11.011] [PMID: 25449454]
[12]
Pandey A, Tripathi Y. Ethnobotany and its relevance in contemporary research. J Med Plants Stud 2017; 5: 123-9.
[13]
Bekalo TH, Woodmatas SD, Woldemariam ZA. An ethnobotanical study of medicinal plants used by local people in the lowlands of Konta Special Woreda, southern nations, nationalities and peoples regional state, Ethiopia. J Ethnobiol Ethnomed 2009; 5(1): 26.
[http://dx.doi.org/10.1186/1746-4269-5-26] [PMID: 19775482]
[14]
Tiwari D, Sah AN, Bawari S, Bussmann RW. Ethnobotanical investigations on plants used in folk medicine by native people of Kumaun Himalayan Region of India. J Ethnobotany Res Appl 2020; 2020(20): 35.
[15]
Das S, Datta R, Nandy S. Phytochemical screening and evaluation of anti-inflammatory activity of methanolic extract of Abroma augusta Linn. Asian Pac J Trop Dis 2012; 2: S114-7.
[http://dx.doi.org/10.1016/S2222-1808(12)60135-2]
[16]
Gupta B, Nayak S, Solanki S. Abroma augusta Linn f: A review. Pharm Sin 2011; 2(4): 253-61.
[17]
Chaudhari KS, Sharma R, Pawar PS, Kashikar V. Pharmacological activities of Abrus precatorius Linn.-a review. Int J Ayurvedic Herbal Med 2012; 2(2): 336-48.
[18]
Garaniya N, Bapodra A. Ethno botanical and phytophrmacological potential of Abrus precatorius L.: A review. Asian Pac J Trop Biomed 2014; 4 (Suppl. 1): S27-34.
[http://dx.doi.org/10.12980/APJTB.4.2014C1069] [PMID: 25183095]
[19]
Shourie A, Kalra K. Analysis of phytochemical constituents and pharmacological properties of Abrus precatorius L. Int J Pharma Bio Sci 2013; 4: 91-101.
[20]
Solanki A, Zaveri M. Pharmacognosy, phytochemistry and pharmacology of Abrus precatorius leaf: A review. Int J Pharm Sci Rev Res 2012; 13(2): 71-6.
[21]
Sujit K, Tanusri B, Sourav P, Jadupati M, Amites G, Amitava G. Pharmacognostical studies and chromatographic evaluation of the differ-ent extracts of Abrus precatorius Linn. Int J Pharm Res Dev 2012; 4(3): 225-33.
[22]
Mahalik G, Jali P, Satapathy KB, Sahoo S. Review on ethnomedicinal, pharmacological and phytochemical constituents of Abutilon indi-cum (L.) Sweet. J Gujarat Res Society 2019; 21(2): 334-40.
[23]
Prabahar A, Boovizhikannan T, Arunkanth C, Kumar S, Murugesan K, Ramadoss K. Antibacterial activity of various extracts of Abutilon indicum (L.) sweet leaves. J Pharm Res 2009; 2(8): 1324-5.
[24]
Shekshavali T, Roshan S. A review on pharmacological activities of Abutilon indicum (Atibala). Res J Pharmacol Pharmacodyn 2016; 8(4): 171-4.
[http://dx.doi.org/10.5958/2321-5836.2016.00031.8]
[25]
Devi SA, Ganjewala D. Antimicrobial activity of Acorus calamus (L.) rhizome and leaf extract. Acta Biol Szeged 2009; 53(1): 45-9.
[26]
Parab RS, Mengi SA. Hypolipidemic activity of Acorus calamus L. in rats. Fitoterapia 2002; 73(6): 451-5.
[http://dx.doi.org/10.1016/S0367-326X(02)00174-0] [PMID: 12385866]
[27]
Kim H, Han T-H, Lee S-G. Anti-inflammatory activity of a water extract of Acorus calamus L. leaves on keratinocyte HaCaT cells. J Ethnopharmacol 2009; 122(1): 149-56.
[http://dx.doi.org/10.1016/j.jep.2008.12.011] [PMID: 19146941]
[28]
Shrivastava N, Srivastava A, Banerjee A, Nivsarkar M. Anti-ulcer activity of Adhatoda vasica Nees. J Herb Pharmacother 2006; 6(2): 43-9.
[http://dx.doi.org/10.1080/J157v06n02_04] [PMID: 17182484]
[29]
Chakraborty A, Brantner AH. Study of alkaloids from Adhatoda vasica Nees on their antiinflammatory activity. Phytother Res 2001; 15(6): 532-4.
[http://dx.doi.org/10.1002/ptr.737] [PMID: 11536385]
[30]
Singh B, Sharma RA. Anti-inflammatory and antimicrobial properties of pyrroloquinazoline alkaloids from Adhatoda vasica Nees. Phytomedicine 2013; 20(5): 441-5.
[http://dx.doi.org/10.1016/j.phymed.2012.12.015] [PMID: 23357363]
[31]
Rana BK, Singh UP, Taneja V. Antifungal activity and kinetics of inhibition by essential oil isolated from leaves of Aegle marmelos. J Ethnopharmacol 1997; 57(1): 29-34.
[http://dx.doi.org/10.1016/S0378-8741(97)00044-5] [PMID: 9234162]
[32]
Baliga MS, Bhat HP, Pereira MM, Mathias N, Venkatesh P. Radioprotective effects of Aegle marmelos (L.) Correa (Bael): A concise re-view. J Altern Complement Med 2010; 16(10): 1109-16.
[http://dx.doi.org/10.1089/acm.2009.0604] [PMID: 20932194]
[33]
Jagetia GC, Venkatesh P. Radioprotection by oral administration of Aegle marmelos (L.) Correa in vivo. J Environ Pathol Toxicol Oncol 2005; 24(4): 315-32.
[http://dx.doi.org/10.1615/JEnvironPatholToxicolOncol.v24.i4.80] [PMID: 16393124]
[34]
Joshi P, Patil R, Maheshwari V. In vitro antidiarrhoeal activity and toxicity profile of Aegle marmelos Correa ex Roxb. dried fruit pulp. Indian J Nat Prod Radiance (IJNPR) 2009; 8(5): 498-502.
[35]
Kumar G, Karthik L, Rao KVB. Phytochemical composition and in vitro antioxidant activity of aqueous extract of Aerva lanata (L.) Juss. ex Schult. Stem (Amaranthaceae). Asian Pac J Trop Med 2013; 6(3): 180-7.
[http://dx.doi.org/10.1016/S1995-7645(13)60020-6] [PMID: 23375030]
[36]
Murugan M, Mohan VR. Phytochemical, FT-IR and antibacterial activity of whole plant extract of Aerva lanata (L.). Juss Ex Schult J Med Plants Stud 2014; 4(3): 51-7.
[37]
Rajesh R, Chitra K, Paarakh PM, Chidambaranathan N. Anticancer activity of aerial parts of Aerva lanata Linn Juss ex Schult against Dal-ton’s ascitic lymphoma. Eur J Integr Med 2011; 3(3): e245-50.
[http://dx.doi.org/10.1016/j.eujim.2011.05.001]
[38]
Kamboj A, Saluja AK. Ageratum conyzoides L.: A review on its phytochemical and pharmacological profile. Inter J Green Pharm 2008; 2(2): 59.
[http://dx.doi.org/10.4103/0973-8258.41171]
[39]
Nour AM, Khalid SA, Kaiser M, Brun R, Abdalla WE, Schmidt TJ. The antiprotozoal activity of methylated flavonoids from Ageratum conyzoides L. J Ethnopharmacol 2010; 129(1): 127-30.
[http://dx.doi.org/10.1016/j.jep.2010.02.015] [PMID: 20219663]
[40]
Moura AC, Silva EL, Fraga MC, Wanderley AG, Afiatpour P, Maia MB. Antiinflammatory and chronic toxicity study of the leaves of Ag-eratum conyzoides L. in rats. Phytomedicine 2005; 12(1-2): 138-42.
[http://dx.doi.org/10.1016/j.phymed.2003.12.003] [PMID: 15693721]
[41]
Madhu Katyayani B, Mallikarjuna Rao P, Muralichand G, et al. Antimicrobial activity of bark of Alangium salvifoloium Linn. F Indian J Microbiol 2002; 42(1): 87-9.
[42]
Wuthi-udomlert M, Prathanturarug S, Wongkrajang Y. Antifungal activity and local toxicity study of Alangium salviifolium subsp. hex-apetalum. Southeast Asian J Trop Med Public Health 2002; 33 (Suppl. 3): 152-4.
[PMID: 12971498]
[43]
Valsaraj R, Pushpangadan P, Smitt UW, Adsersen A, Nyman U. Antimicrobial screening of selected medicinal plants from India. J Ethnopharmacol 1997; 58(2): 75-83.
[http://dx.doi.org/10.1016/S0378-8741(97)00085-8] [PMID: 9406894]
[44]
Jain VC, Patel N, Shah DP, Patel PK, Joshi BH. Antioxidant and antimicrobial activities of Alangium salvifolium (Lf) Wang root. Glob J Pharmacol 2010; 4(1): 13-8.
[45]
Karigar A, Shariff W, Sikarwar M. Wound healing property of alcoholic extract of leaves of Alangium salvifolium. J Pharm Res 2010; 3(2): 267-9.
[46]
Tanwer BS, Vijayvergia R. Biological evaluation of Alangium salviifolium (LF) Wangerin. J Chem Pharm Res 2014; 6(12): 611-8.
[47]
Ye C-L, Dai D-H, Hu W-L. Antimicrobial and antioxidant activities of the essential oil from onion (Allium cepa L.). Food Control 2013; 30(1): 48-53.
[http://dx.doi.org/10.1016/j.foodcont.2012.07.033]
[48]
Hughes BG, Lawson LD. Antimicrobial effects of Allium sativum L.(garlic), Allium ampeloprasum L.(elephant garlic), and Allium cepa L.(onion), garlic compounds and commercial garlic supplement products. Phytother Res 1991; 5(4): 154-8.
[http://dx.doi.org/10.1002/ptr.2650050403]
[49]
Greeshma K, Muthulingam S, Thamizselvi R, Venkatamani GP. Phytochemical analysis and a review on biological importance of Allium cepa. L. GSC Advanc Res Rev 2020; 2(2): 018-24.
[50]
Akhtar MS, Khan MA, Malik MT. Hypoglycaemic activity of Alpinia galanga rhizome and its extracts in rabbits. Fitoterapia 2002; 73(7-8): 623-8.
[http://dx.doi.org/10.1016/S0367-326X(02)00235-6] [PMID: 12490221]
[51]
Chouni A, Paul S. A review on phytochemical and pharmacological potential of Alpinia galanga Pharmacogn J 2018; 10(1): 09-15.
[http://dx.doi.org/10.5530/pj.2018.1.2]
[52]
Hilou A, Nacoulma OG, Guiguemde TR. in vivo antimalarial activities of extracts from Amaranthus spinosus L. and Boerhaavia erecta L. in mice. J Ethnopharmacol 2006; 103(2): 236-40.
[http://dx.doi.org/10.1016/j.jep.2005.08.006] [PMID: 16171960]
[53]
Kumar BSA, Lakshman K, Jayaveera K, Shekar DS, Kumar AA, Manoj B. Antioxidant and antipyretic properties of methanolic extract of Amaranthus spinosus leaves. Asian Pac J Trop Med 2010; 3(9): 702-6.
[http://dx.doi.org/10.1016/S1995-7645(10)60169-1]
[54]
Zeashan H, Amresh G, Singh S, Rao CV. Hepatoprotective activity of Amaranthus spinosus in experimental animals. Food Chem Toxicol 2008; 46(11): 3417-21.
[http://dx.doi.org/10.1016/j.fct.2008.08.013] [PMID: 18783728]
[55]
Sangameswaran B, Jayakar B. Anti-diabetic, anti-hyperlipidemic and spermatogenic effects of Amaranthus spinosus Linn. on streptozoto-cin-induced diabetic rats. J Nat Med 2008; 62(1): 79-82.
[http://dx.doi.org/10.1007/s11418-007-0189-9] [PMID: 18404348]
[56]
Akinpelu DA, Ojewole J. Antimicrobial activity of Anacardium occidentale bark. Fitoterapia 2001; 72(3): 286-7.
[http://dx.doi.org/10.1016/S0367-326X(00)00310-5] [PMID: 11295307]
[57]
Padhi L, Panda S, Satapathy S, Dutta S. In vitro evaluation of antibacterial potential of Annona squamosa L. and Annona reticulata L. from Similipal Biosphere Reserve, Orissa, India. Agric Technol Thail 2011; 7(1): 133-42.
[58]
Rout SP, Kar DM, Mohapatra SB, Swain SP. Anti-hyperglycemic effect Annona reticulata L. leaves on experimental diabetic rat model. Asian J Pharm Clin Res 2013; 6(1): 56-60.
[59]
Rahman SM, Rashedul M, Rahman S, Mosaiab T, Ahmed R, Khatun F. Antihyperglycemic studies with methanol extract of Annona reticu-lata L.(Annonaceae) and Carissa carandas L.(Apocynaceae) leaves in Swiss albino mice. Adv Nat Appl Sci 2011; 5(2): 218-22.
[60]
Gupta RK, Kesari AN, Murthy PS, Chandra R, Tandon V, Watal G. Hypoglycemic and antidiabetic effect of ethanolic extract of leaves of Annona squamosa L. in experimental animals. J Ethnopharmacol 2005; 99(1): 75-81.
[http://dx.doi.org/10.1016/j.jep.2005.01.048] [PMID: 15848023]
[61]
Chavan MJ, Wakte PS, Shinde DB. Analgesic and anti-inflammatory activity of Caryophyllene oxide from Annona squamosa L. bark. Phytomedicine 2010; 17(2): 149-51.
[http://dx.doi.org/10.1016/j.phymed.2009.05.016] [PMID: 19576741]
[62]
Gupta RK, Kesari AN, Watal G, et al. Hypoglycaemic and antidiabetic effect of aqueous extract of leaves of Annona squamosa (L.) in experimental animal. Curr Sci 2005; 1244-54.
[63]
Alam MA, Subhan N, Chowdhury SA, et al. Anthocephalus cadamba (Roxb.) Miq., Rubiaceae, extract shows hypoglycemic effect and eases oxidative stress in alloxan-induced diabetic rats. Rev Bras Farmacogn 2011; 21(1)
[http://dx.doi.org/10.1590/S0102-695X2011005000033]
[64]
Kaur S, Kumar S. Studies on the genoprotective/antioxidant potential of methanol extract of Anthocephalus cadamba (Roxb.) Miq. J Med Plants Res 2011; 5(19): 4764-70.
[65]
Chandel M, Kumar M, Sharma U, Singh B, Kaur S. Investigations on antioxidant, antiproliferative and cox-2 inhibitory potential of alka-loids from Anthocephalus cadamba (roxb.) miq. leaves. Chem Biodivers 2017; 14(4): e1600376.
[http://dx.doi.org/10.1002/cbdv.201600376] [PMID: 27973724]
[66]
Sareedenchai V, Wiwat C, Wongsinkongman P, Soonthornchareonnon N. In vitro testing of anti-HIV and antioxidative activities of Ar-gyreia nervosa (Burm. f) Bojor leaves. Pharml Sci Asia 2014; 41: 47-53.
[67]
Islam S, Shajib MS, Rashid RB, et al. Antinociceptive activities of Artocarpus lacucha Buch-ham (Moraceae) and its isolated phenolic compound, catechin, in mice. BMC Complement Altern Med 2019; 19(1): 214.
[http://dx.doi.org/10.1186/s12906-019-2565-x] [PMID: 31412852]
[68]
Jagtap UB, Bapat VA. Artocarpus: A review of its traditional uses, phytochemistry and pharmacology. J Ethnopharmacol 2010; 129(2): 142-66.
[http://dx.doi.org/10.1016/j.jep.2010.03.031] [PMID: 20380874]
[69]
Kitisripanya T, Inyai C, Krittanai S, et al. A monoclonal antibody-based immunoassay for the determination of oxyresveratrol from Arto-carpus lacucha Buch.-Ham. J Nat Med 2017; 71(3): 523-30.
[http://dx.doi.org/10.1007/s11418-017-1083-8] [PMID: 28364228]
[70]
Cabrini DA, Moresco HH, Imazu P, et al. Analysis of the potential topical anti-inflammatory activity of Averrhoa carambola L. in mice. Evid Based Complement Alternat Med 2011; 2011.
[71]
Islam S, Alam MB, Ahmed A, Lee S, Lee S-H, Kim S. Identification of secondary metabolites in Averrhoa carambola L. bark by high-resolution mass spectrometry and evaluation for α-glucosidase, tyrosinase, elastase, and antioxidant potential. Food Chem 2020; 332: 127377.
[http://dx.doi.org/10.1016/j.foodchem.2020.127377] [PMID: 32619942]
[72]
Moresco HH, Queiroz GS, Pizzolatti MG, Brighente I. Chemical constituents and evaluation of the toxic and antioxidant activities of Aver-rhoa carambola leaves. Rev Bras Farmacogn 2012; 22(2): 319-24.
[http://dx.doi.org/10.1590/S0102-695X2011005000217]
[73]
Kaur M, Singh G, Mohan C. Barringtonia acutangula: A traditional medicinal plant. Int J Pharm Sci Rev Res 2013; 23(1): 168-71.
[74]
Padmavathi D, Suseela L, Bharathi RV. Antidiarrheal activity of ethanolic extract of leaves of Barringtonia acutangula (L) gaertn Inventi Impact: Ethnopharmacology 2010 Available from: http: inventi.in/journal/article/3/23/Inventi%20Impact:%20Ethnopharmacology/Pharmaceutical
[75]
Florida M, Nair A, Sekar T. Apoptotic induction by leaf extracts of Barringtonia acutangula L. and Stereospermum colais L. Colo320 cells. Int J Curr Res 2012; 4(07): 130-3.
[76]
Kathirvel A, Sujatha V. Phytochemical analysis and antioxidant activity of Barringtonia acutangula (L.) Gaertn. leaves. Int J Pharm Pharm Sci 2012; 4(2): 277-81.
[77]
Quader SH, Islam SU, Saifullah A, Majumder FU, Hannan J. Evaluation of the anti-nociceptive and anti-inflammatory activities of the ethanolic extract of Barringtonia acutangula Linn. (lecythidaceae) roots. Int J Pharm Sci Rev Res 2013; 20(2): 24-32.
[78]
Deka J, Borah U, Dash B, Dash S, Kalita L. Preliminary phytochemical screening and in vitro antimicrobial activity of ethanolic extract of stem of the herb Basella alba L. var rubra (L.) stewart (family-basellaceae). Int J Curr Pharm Res 2017; 9(3): 91-4.
[http://dx.doi.org/10.22159/ijcpr.2017.v9i3.19599]
[79]
Divya J, Kumar A, Kumar R. Evaluation of diuretic and sedative activity for ethanolic leaves extract of Basella alba L var rubra. WJCMPR 2020; pp. 74-84.
[80]
Shilpi JA, Taufiq-Ur-Rahman M, Uddin SJ, Alam MS, Sadhu SK, Seidel V. Preliminary pharmacological screening of Bixa orellana L. leaves. J Ethnopharmacol 2006; 108(2): 264-71.
[http://dx.doi.org/10.1016/j.jep.2006.05.008] [PMID: 16963211]
[81]
Vilar DdA, Vilar MSdA, Raffin FN, et al. Traditional uses, chemical constituents, and biological activities of Bixa orellana L.: A review. Sci World J 2014; 2014: 857292.
[82]
Satheesh MA, Pari L. Antioxidant effect of Boerhavia diffusa L. in tissues of alloxan induced diabetic rats. Indian J Exp Biol 2004; 42(10): 989-92.
[83]
Pari L, Amarnath Satheesh M. Antidiabetic effect of Boerhavia diffusa: Effect on serum and tissue lipids in experimental diabetes. J Med Food 2004; 7(4): 472-6.
[http://dx.doi.org/10.1089/jmf.2004.7.472] [PMID: 15671692]
[84]
Akinnibosun F, Akinnibosun H, Ogedegbe D. Investigation on the antibacterial activity of the aqueous and ethanolic extracts of the leaves of Boerhavia diffusa L. ScientificWorldJ 2009; 4(2): 15-8.
[85]
Kaur H. Boerhaavia diffusa: Bioactive compounds and pharmacological activities. Biomed Pharmacol J 2019; 12(4): 1675-82.
[http://dx.doi.org/10.13005/bpj/1797]
[86]
Saleem R, Ahmad M, Hussain SA, et al. Hypotensive, hypoglycaemic and toxicological studies on the flavonol C-glycoside shamimin from Bombax ceiba. Planta Med 1999; 65(4): 331-4.
[http://dx.doi.org/10.1055/s-1999-14060] [PMID: 10364838]
[87]
Bhavsar C, Talele GS. Potential anti-diabetic activity of Bombax ceiba. Bangladesh J Pharmacol 2013; 8(2): 102-6.
[http://dx.doi.org/10.3329/bjp.v8i2.13701]
[88]
Paschapur MS, Patil M, Kumar R, Patil SR. Evaluation of antiinflammatory activity of ethanolic extract of Borassus flabellifer L. male flowers (inflorescences) in experimental animals. J Med Plant Res 2009; 3(2): 049-54.
[89]
Paschapur MS, Patil S, Patil SR, Kumar R, Patil M. Evaluation of the analgesic and antipyretic activities of ethanolic extract of male flowers (inflorescences) of Borassus flabellifer L.(Arecaceae). Int J Pharm Pharm Sci 2009; 1(2): 98-106.
[90]
Agrawal MK, Rathore D, Goyal S, Varma A, Varma A. Antibacterial efficacy of Brassica campestris root, stem and leaves extracts. Int J Adv Res (Indore) 2013; 1(5): 131-5.
[91]
Nawaz H, Shad MA, Muzaffar S. Phytochemical composition and antioxidant potential of Brassica In: El-Esawi MA, Ed Brassica germplasm: Characterization, breeding and utilization London: IntechOpen 2018; p. 8.
[92]
Pattnaik A, Sarkar R, Sharma A, et al. Pharmacological studies on Buchanania lanzan Spreng.- a focus on wound healing with particular reference to anti-biofilm properties. Asian Pac J Trop Biomed 2013; 3(12): 967-74.
[http://dx.doi.org/10.1016/S2221-1691(13)60187-2] [PMID: 24093788]
[93]
Kodati D, Pareta S, Patra KC. Antiulcer activity of ethanolic extract of Buchanania lanzan Spreg. Roots. Ann Biol Res 2010; 1(4): 234-9.
[94]
Kodati D, Pareta SK, Patnaik A. Antidiarrhoeal activity of alcoholic extract of Buchanania lanzan Spreng. roots. Pharmacologyonline 2010; 3: 720-6.
[95]
Sushma N, Smitha PV, Gopal YV, et al. Antidiabetic, antihyperlipidemic and antioxidant activities of Buchanania lanzan spreng methanol leaf extract in streptozotocin-induced types I and II diabetic rats. Trop J Pharm Res 2013; 12(2): 221-6.
[http://dx.doi.org/10.4314/tjpr.v12i2.14]
[96]
Tsai S-C, Liang Y-H, Chiang J-H, et al. Anti-inflammatory effects of Calophyllum inophyllum L. in RAW264.7 cells. Oncol Rep 2012; 28(3): 1096-102.
[http://dx.doi.org/10.3892/or.2012.1873] [PMID: 22735972]
[97]
Yimdjo MC, Azebaze AG, Nkengfack AE, Meyer AM, Bodo B, Fomum ZT. Antimicrobial and cytotoxic agents from Calophyllum in-ophyllum. Phytochemistry 2004; 65(20): 2789-95.
[http://dx.doi.org/10.1016/j.phytochem.2004.08.024] [PMID: 15474565]
[98]
Balekari U, Veeresham C. In vivo and in vitro evaluation of anti diabetic and insulin Secretagogue activities of Capparis zeylanica. Pharmacol Pharm 2015; 6(7): 311-20.
[http://dx.doi.org/10.4236/pp.2015.67033]
[99]
Ghule BV, Murugananthan G, Nakhat PD, Yeole PG. Immunostimulant effects of Capparis zeylanica Linn. leaves. J Ethnopharmacol 2006; 108(2): 311-5.
[http://dx.doi.org/10.1016/j.jep.2006.03.041] [PMID: 16766150]
[100]
Mishra S, Singh P, Dubey S. Evaluation of CNS depressant activity of Capparis zeylanica Lin. root. Res J Med Plant 2011; 5(6): 738-46.
[http://dx.doi.org/10.3923/rjmp.2011.738.746]
[101]
Tlili N, Elfalleh W, Saadaoui E, Khaldi A, Triki S, Nasri N. The caper (Capparis L.): Ethnopharmacology, phytochemical and pharmaco-logical properties. Fitoterapia 2011; 82(2): 93-101.
[http://dx.doi.org/10.1016/j.fitote.2010.09.006] [PMID: 20851750]
[102]
Phongpaichit S, Pujenjob N, Rukachaisirikul V, Ongsakul M. Antifungal activity from leaf extracts of Cassia alata L., Cassia fistula L. and Cassia tora L. Songklanakarin J Sci Technol 2004; 26(5): 741-8.
[103]
Makinde A, Igoli J. Ta’Ama L, Shaibu S, Garba A. Antimicrobial activity of Cassia alata. Afr J Biotechnol 2007; 6(13): 1509-10.
[104]
Ibrahim D, Osman H. Antimicrobial activity of Cassia alata from Malaysia. J Ethnopharmacol 1995; 45(3): 151-6.
[http://dx.doi.org/10.1016/0378-8741(94)01200-J] [PMID: 7623478]
[105]
Kundu S, Roy S, Lyndem LM. Cassia alata L: Potential role as anthelmintic agent against Hymenolepis diminuta. Parasitol Res 2012; 111(3): 1187-92.
[http://dx.doi.org/10.1007/s00436-012-2950-6] [PMID: 22576858]
[106]
Yadav JP, Arya V, Yadav S, Panghal M, Kumar S, Dhankhar S. Cassia occidentalis L.: A review on its ethnobotany, phytochemical and pharmacological profile. Fitoterapia 2010; 81(4): 223-30.
[http://dx.doi.org/10.1016/j.fitote.2009.09.008] [PMID: 19796670]
[107]
Arya V, Yadav S, Kumar S, Yadav J. Antimicrobial activity of Cassia occidentalis L (leaf) against various human pathogenic microbes. Life Sci Med Res 2010; 9(1): e12.
[108]
Sheeba M, Emmanuel S, Revathi K, Ignacimuthu S. Wound healing activity of Cassia occidentalis L. in albino Wistar rats. Int J Integr Biol 2009; 8(1): 1-6.
[109]
Schedlbauer MD, Klekowski EJ Jr. Antheridogen activity in the fern Ceratopteris thalictroides (L.) Brongn. Bot J Linn Soc 1972; 65(4): 399-413.
[http://dx.doi.org/10.1111/j.1095-8339.1972.tb02280.x]
[110]
Verspohl EJ, Bauer K, Neddermann E. Antidiabetic effect of Cinnamomum cassia and Cinnamomum zeylanicum in vivo and In vitro. Phytother Res 2005; 19(3): 203-6.
[http://dx.doi.org/10.1002/ptr.1643] [PMID: 15934022]
[111]
Kamath JV, Rana AC, Chowdhury AR. Pro-healing effect of Cinnamomum zeylanicum bark. Phytother Res 2003; 17(8): 970-2.
[http://dx.doi.org/10.1002/ptr.1293] [PMID: 13680838]
[112]
Ranasinghe P, Pigera S, Premakumara GA, Galappaththy P, Constantine GR, Katulanda P. Medicinal properties of ‘true’ cinnamon (Cin-namomum zeylanicum): A systematic review. BMC Complement Altern Med 2013; 13(1): 275.
[http://dx.doi.org/10.1186/1472-6882-13-275] [PMID: 24148965]
[113]
Ngoci NS, Ramadhan M, Ngari MS, Leonard OP. Screening for antimicrobial activity of Cissampelos pareira L. methanol root extract. European J Med Plants 2014; 4(1): 45-51.
[http://dx.doi.org/10.9734/EJMP/2014/5464]
[114]
Amresh G, Rao CV, Singh PN. Antioxidant activity of Cissampelos pareira on benzo (a) pyrene-induced mucosal injury in mice. Nutr Res 2007; 27(10): 625-32.
[http://dx.doi.org/10.1016/j.nutres.2007.05.009]
[115]
Surendran S, Eswaran MB, Vijayakumar M, Rao CV. In vitro and in vivo hepatoprotective activity of Cissampelos pareira against carbon-tetrachloride induced hepatic damage. Indian J Exp Biol 2011; 49(12): 939-45.
[116]
Amresh G, Reddy GD, Rao ChV, Singh PN. Evaluation of anti-inflammatory activity of Cissampelos pareira root in rats. J Ethnopharmacol 2007; 110(3): 526-31.
[http://dx.doi.org/10.1016/j.jep.2006.10.009] [PMID: 17097249]
[117]
Devi BP, Boominathan R, Mandal SC. Evaluation of anti-diarrheal activity of Cleome viscosa L. extract in rats. Phytomedicine 2002; 9(8): 739-42.
[http://dx.doi.org/10.1078/094471102321621368] [PMID: 12587696]
[118]
Ahmed S, Sultana M, Mohtasheem M, Hasan U, Azhar I. Analgesic and antiemetic activity of Cleome viscosa L. Pakistan J Botany 2011. Available from:https://hal.archives-ouvertes.fr/hal-01760967
[119]
Parimaladevi B, Boominathan R, Mandal SC. Studies on analgesic activity of Cleome viscosa in mice. Fitoterapia 2003; 74(3): 262-6.
[http://dx.doi.org/10.1016/S0367-326X(03)00020-0] [PMID: 12727491]
[120]
Lakshmanan G, Sathiyaseelan A, Kalaichelvan P, Murugesan K. Plant-mediated synthesis of silver nanoparticles using fruit extract of Cleome viscosa L.: Assessment of their antibacterial and anticancer activity. Karbala Int J Modern Sci 2018; 4(1): 61-8.
[http://dx.doi.org/10.1016/j.kijoms.2017.10.007]
[121]
Yankanchi S, Koli S. Anti-inflammatory and analgesic activity of mature leaves methanol extract of Clerodendrum inerme L.(Gaertn). J Pharm Sci Res 2010; 2(11): 782.
[122]
Rajeev P, Kumar Y, Gupta S. Anti-diabetic activity of Clerodendrum (or Clerodendron) inerme using in vivo and in vitro studies, novel science. Int J Pharma Sci 2012; 1(6): 298-302.
[123]
Thirumal M, Srimanthula S, Kishore G, Vadivelan R, Anand Kumar A. Analgesic and antipyretic effects of aqueous extract from Clerodendrum inerme (L.) Gaertn. leaves in animal models. Pharm Lett 2013; 5(2): 315-23.
[124]
Anandhi K, Ushadevi T. Analysis of phytochemical constituents and antibacterial activities of Clerodendrum inerme L. against some se-lected pathogens. IJBAF 2013; 1(7): 387-93.
[125]
Sangeetha M, Kousalya K, Lavanya R, Sowmya C, Chamundeeswari D, Maheswara U. In-vitro anti-inflammatory and anti-arthritic activity of leaves of Cleodendron inerme. Res J Pharm Biol Chem Sci 2011; 2(1): 822-7.
[126]
Prasad M, Sushant S, Chikkaswamy B. Phytochemical analysis, antioxidant potential, antibacterial activity and molecular characterization of Clerodendrum species. J Mol Biol 2012; 3(3): 71-6.
[127]
Al-Snafi AE. Chemical constituents and pharmacological effects of Clerodendrum inerme-A review. SMU Med J 2016; 3(1): 129-53.
[128]
Logesh R, Das N, Adhikari-Devkota A, Devkota HP. Cocculus hirsutus (L.) W.Theob. (Menispermaceae): A review on traditional uses, phytochemistry and pharmacological activities. Medicines (Basel) 2020; 7(11): 69.
[http://dx.doi.org/10.3390/medicines7110069] [PMID: 33182572]
[129]
Jethva KD, Bhatt DR, Zaveri MN. Antimycobacterial screening of selected medicinal plants against Mycobacterium tuberculosis H37Rv using agar dilution method and the microplate resazurin assay. Int J Mycobacteriol 2020; 9(2): 150-5.
[PMID: 32474536]
[130]
Gupta VK, Kaushik A, Chauhan DS, Ahirwar RK, Sharma S, Bisht D. Anti-mycobacterial activity of some medicinal plants used tradition-ally by tribes from Madhya Pradesh, India for treating tuberculosis related symptoms. J Ethnopharmacol 2018; 227: 113-20.
[http://dx.doi.org/10.1016/j.jep.2018.08.031] [PMID: 30172059]
[131]
Brahmam P, Sunita K. Phytochemical investigation and in vitro antimalarial activity of Acalypha indica (L.) and Cocculus hirsutus (L.) From Prakasam district, Andhra Pradesh, India. Biomed Pharmacol J 2018; 11(4): 2123-34.
[http://dx.doi.org/10.13005/bpj/1592]
[132]
Elango G, Rahuman AA, Bagavan A, Kamaraj C, Zahir AA, Venkatesan C. Laboratory study on larvicidal activity of indigenous plant extracts against Anopheles subpictus and Culex tritaeniorhynchus. Parasitol Res 2009; 104(6): 1381-8.
[http://dx.doi.org/10.1007/s00436-009-1339-7] [PMID: 19165502]
[133]
De Wet H, Fouché G, Van Heerden F. In vitro cytotoxicity of crude alkaloidal extracts of South African Menispermaceae against three cancer cell lines. Afr J Biotechnol 2009; 8(14): 3332-5.
[134]
Thavamani BS, Mathew M, Dhanabal SP. In vitro cytotoxic activity of menispermaceae plants against HeLa cell line. Anc Sci Life 2013; 33(2): 81-4.
[PMID: 25284939]
[135]
Arunabha M, Satish N. Study the immunomodulatory effects of combined extracts of Sesbania grandiflora flowers and Cocculus hirsutus leaves on the circulating antibody response. Am J Phytomed Clin Ther 2015; 3(3): 199-208.
[136]
Sangameswaran B, Jayakar B. Anti-diabetic and spermatogenic activity of Cocculus hirsutus (L) Diels. Afr J Biotechnol 2007; 6(10): 1213-6.
[137]
Kumaran A. Joel karunakaran R. Antioxidant and free radical scavenging activity of an aqueous extract of Coleus aromaticus. Food Chem 2006; 97(1): 109-14.
[http://dx.doi.org/10.1016/j.foodchem.2005.03.032]
[138]
Rao DS, Rao VP, Rao KS. Pharmacological effects of forskolin isolated from Coleus aromaticus on the lung damage rats. Inter J Adv Pharm Sci 2010; 1(1): 17-21.
[139]
Rout OP, Acharya R, Mishra SK, Sahoo R. Pathorchur (Coleus aromaticus): A review of the medicinal evidence for its phytochemistry and pharmacology properties. Int J Appl Biol Pharm Technol 2012; 3(4): 348-55.
[140]
Thenmozhi S, Bhuvana M, John SA. Screening of antimicrobial and phytochemical investigation of Coleus aromaticus (Benth) leaf against five respiratory pathogens. J Pharm Res 2011; 7: 2261-2.
[141]
Pinheiro MM, Fernandes SB, Fingolo CE, Boylan F, Fernandes PD. Anti-inflammatory activity of ethanol extract and fractions from Couroupita guianensis Aublet leaves. J Ethnopharmacol 2013; 146(1): 324-30.
[http://dx.doi.org/10.1016/j.jep.2012.12.053] [PMID: 23313951]
[142]
Gousia S, Kumar KA, Kumar TV, Latha JNL. Biological activities and medicinal properties of Couroupita guianensis. Inter J Pharm Pharm Sci Res 2013; 3(4): 140-3.
[143]
Umachigi SP, Jayaveera K, Ashok Kumar C, Kumar G. Antimicrobial, wound healing and antioxidant potential of Couroupita guianensis in rats. Pharmacologyonline 2007; 3: 269-81.
[144]
Ramalakshmi C, Ranjitsingh A, Kalirajan K, Kalirajan A, Athinarayanan G, Mariselvam R. A preliminary screening of the medicinal plant Couroupita guianensis for its antimicrobial potential against clinical and fish-borne pathogens. Elixir Appl Biol 2013; 57: 14055-7.
[145]
Costa DCM, Azevedo MMB, Silva DOE, et al. In vitro anti-MRSA activity of Couroupita guianensis extract and its component Tryptan-thrin. Nat Prod Res 2017; 31(17): 2077-80.
[http://dx.doi.org/10.1080/14786419.2016.1272110] [PMID: 28013553]
[146]
Ahmad A, Tandon S, Xuan TD, Nooreen Z. A review on phytoconstituents and biological activities of Cuscuta species. Biomed Pharmacother 2017; 92: 772-95.
[http://dx.doi.org/10.1016/j.biopha.2017.05.124] [PMID: 28591690]
[147]
Patel S, Sharma V, Chauhan NS, Dixit VK. An updated review on the parasitic herb of Cuscuta Reflexa Roxb. J Chin Integr Med 2012; 10(3): 249-55.
[http://dx.doi.org/10.3736/jcim20120302] [PMID: 22409913]
[148]
Mahmood N, Piacente S, Burke A, Khan A, Pizza C. Constituents of Cuscuto reflexa are anti-HIV Agents. Antivir Chem Chemother 1997; 8(1): 70-4.
[http://dx.doi.org/10.1177/095632029700800108]
[149]
Suresh V, Sruthi V, Padmaja B, Asha VV. In vitro anti-inflammatory and anti-cancer activities of Cuscuta reflexa Roxb. J Ethnopharmacol 2011; 134(3): 872-7.
[http://dx.doi.org/10.1016/j.jep.2011.01.043] [PMID: 21295129]
[150]
Chatterjee D, Sahu RK, Jha AK, Dwivedi J. Evaluation of antitumor activity of Cuscuta Reflexa Roxb (Cuscutaceae) against Ehrlich ascites carcinoma in Swiss albino mice. Trop J Pharm Res 2011; 10(4): 447-54.
[http://dx.doi.org/10.4314/tjpr.v10i4.10]
[151]
Dande P, Khan A. Evaluation of wound healing potential of Cynodon dactylon. Asian J Pharm Clin Res 2012; 5(3): 161-4.
[152]
Singh SK, Kesari AN, Gupta RK, Jaiswal D, Watal G. Assessment of antidiabetic potential of Cynodon dactylon extract in streptozotocin diabetic rats. J Ethnopharmacol 2007; 114(2): 174-9.
[http://dx.doi.org/10.1016/j.jep.2007.07.039] [PMID: 17889469]
[153]
Krishnamoorthy M, Ashwini P. Anticancer activity of Cynodon dactylon L. extract on Ehrlich ascites carcinoma. J Environ Res Dev 2011; 5(3): 551-7.
[154]
Garg VK, Paliwal SK. Anti-inflammatory activity of aqueous extract of Cynodon dactylon. Int J Pharmacol 2011; 7(3): 370-5.
[http://dx.doi.org/10.3923/ijp.2011.370.375]
[155]
Garg VK, Paliwal SK. Anticonvulsant activity of ethanolic extract of Cynodon dactylon. Pharm Sin 2011; 2(2): 86-90.
[156]
Ashokkumar K, Selvaraj K, Muthukrishnan SD. Cynodon dactylon (L.) Pers.: An updated review of its phytochemistry and pharmacolo-gy. J Med Plants Res 2013; 7(48): 3477-83.
[157]
Rastogi S, Pandey MM, Rawat AKS. An ethnomedicinal, phytochemical and pharmacological profile of Desmodium gangeticum (L.) DC. and Desmodium adscendens (Sw.) DC. J Ethnopharmacol 2011; 136(2): 283-96.
[http://dx.doi.org/10.1016/j.jep.2011.04.031] [PMID: 21530632]
[158]
Govindarajan R, Rastogi S, Vijayakumar M, et al. Studies on the antioxidant activities of Desmodium gangeticum. Biol Pharm Bull 2003; 26(10): 1424-7.
[http://dx.doi.org/10.1248/bpb.26.1424] [PMID: 14519948]
[159]
Jahan FI, Hossain MS, Mamun A, et al. An evaluation of antinociceptive effect of methanol extracts of Desmodium gangeticum (L.) DC. stems and Benincasa hispida (Thunb.) Cogn. leaves on acetic acidinduced gastric pain in mice. Adv Nat Appl Sci 2010; 4(3): 365-9.
[160]
Govindarajan R, Vijayakumar M, Rao ChV, et al. Antiinflammatory and antioxidant activities of Desmodium gangeticum fractions in car-rageenan-induced inflamed rats. Phytother Res 2007; 21(10): 975-9.
[http://dx.doi.org/10.1002/ptr.2199] [PMID: 17604372]
[161]
Govindarajan R, Asare-Anane H, Persaud S, Jones P, Houghton PJ. Effect of Desmodium gangeticum extract on blood glucose in rats and on insulin secretion in vitro. Planta Med 2007; 73(5): 427-32.
[http://dx.doi.org/10.1055/s-2007-967176] [PMID: 17431824]
[162]
Gao H, Kuroyanagi M, Wu L, Kawahara N, Yasuno T, Nakamura Y. Antitumor-promoting constituents from Dioscorea bulbifera L. in JB6 mouse epidermal cells. Biol Pharm Bull 2002; 25(9): 1241-3.
[http://dx.doi.org/10.1248/bpb.25.1241] [PMID: 12230129]
[163]
Wang J, Ji L, Liu H, Wang Z. Study of the hepatotoxicity induced by Dioscorea bulbifera L. rhizome in mice. Biosci Trends 2010; 4(2): 79-85.
[PMID: 20448345]
[164]
Wang J-M, Ji L-L, Branford-White CJ, et al. Antitumor activity of Dioscorea bulbifera L. rhizome in vivo. Fitoterapia 2012; 83(2): 388-94.
[http://dx.doi.org/10.1016/j.fitote.2011.12.001] [PMID: 22178682]
[165]
Mbiantcha M, Kamanyi A, Teponno RB, Tapondjou AL, Watcho P, Nguelefack TB. Analgesic and anti-inflammatory properties of extracts from the bulbils of Dioscorea bulbifera L. var sativa (Dioscoreaceae) in mice and rats. Evid Based Complement Alternat Med 2011; 2011(3): 912935.
[http://dx.doi.org/10.1155/2011/912935] [PMID: 20953397]
[166]
Jahan R, Al-Nahain A, Majumder S, Rahmatullah M. Ethnopharmacological significance of Eclipta alba (L.) hassk.(Asteraceae). Int Sch Res Notices 2014; 2014: 385969.
[167]
Mithun N, Shashidhara S, Vivek Kumar R. Eclipta alba (L.) A review on its phytochemical and pharmacological profile. Pharmacologyonline 2011; 1(1): 345-57.
[168]
Ananthi J, Prakasam A, Pugalendi KV. Antihyperglycemic activity of Eclipta alba leaf on alloxan-induced diabetic rats. Yale J Biol Med 2003; 76(3): 97-102.
[PMID: 15369623]
[169]
Roy RK, Thakur M, Dixit VK. Hair growth promoting activity of Eclipta alba in male albino rats. Arch Dermatol Res 2008; 300(7): 357-64.
[http://dx.doi.org/10.1007/s00403-008-0860-3] [PMID: 18478241]
[170]
Jayathirtha MG, Mishra SH. Preliminary immunomodulatory activities of methanol extracts of Eclipta alba and Centella asiatica. Phytomedicine 2004; 11(4): 361-5.
[http://dx.doi.org/10.1078/0944711041495236] [PMID: 15185851]
[171]
Saxena AK, Singh B, Anand KK. Hepatoprotective effects of Eclipta alba on subcellular levels in rats. J Ethnopharmacol 1993; 40(3): 155-61.
[http://dx.doi.org/10.1016/0378-8741(93)90063-B] [PMID: 8145570]
[172]
Al-Snafi AE. Pharmacology and therapeutic potential of Euphorbia hirta (Syn: Euphorbia pilulifera)-A review. IOSR J Pharm 2017; 7(3): 7-20.
[http://dx.doi.org/10.9790/3013-0703010720]
[173]
Basma AA, Zakaria Z, Latha LY, Sasidharan S. Antioxidant activity and phytochemical screening of the methanol extracts of Euphorbia hirta L. Asian Pac J Trop Med 2011; 4(5): 386-90.
[http://dx.doi.org/10.1016/S1995-7645(11)60109-0] [PMID: 21771682]
[174]
Annamalai A, Christina VL, Sudha D, Kalpana M, Lakshmi PT. Green synthesis, characterization and antimicrobial activity of Au NPs using Euphorbia hirta L. leaf extract. Colloids Surf B Biointerfaces 2013; 108: 60-5.
[http://dx.doi.org/10.1016/j.colsurfb.2013.02.012] [PMID: 23528605]
[175]
Lanhers M-C, Fleurentin J, Dorfman P, Mortier F, Pelt J-M. Analgesic, antipyretic and anti-inflammatory properties of Euphorbia hirta. Planta Med 1991; 57(3): 225-31.
[http://dx.doi.org/10.1055/s-2006-960079] [PMID: 1896520]
[176]
Widharna R, Soemardji A, Wirasutisna K, Kardono L. Anti diabetes mellitus activity in vivo of ethanolic extract and ethyl acetate fraction of Euphorbia hirta L. herb. Int J Pharmacol 2010; 6(3): 231-40.
[http://dx.doi.org/10.3923/ijp.2010.231.240]
[177]
Hossain MS. Evaluation of antimicrobial and cytotoxic activity of the plant extracts of Feronia limonia (Linn). J Sci Innov Res 2013; 2(5): 859-63.
[178]
Patel B, Shrivastava R, Uppadhyay R. Phytochemical and pharmacological studies of root and root bark of Feronia limonia (L.) Swingle. Indian J For 1982; 5: 14-7.
[179]
Srivastava R, Mishra N, Agarwal S, Mishra N. Pharmacological and phytochemical properties of kaitha (Feronia limonia L.): A review. Plant Arch 2019; 19: 608-11.
[180]
Sasidharan SP, Vasumathi AV. In vitro pharmacological, in vivo toxicological and in silico molecular docking analysis of glycopentalone, a novel compound from Glycosmis pentaphylla (Retz.) Correa. Med Chem Res 2017; 26(8): 1697-707.
[http://dx.doi.org/10.1007/s00044-017-1880-3]
[181]
Shoja MH, Reddy ND, Nayak PG, Srinivasan KK, Rao CM. Glycosmis pentaphylla (Retz.) DC arrests cell cycle and induces apoptosis via caspase-3/7 activation in breast cancer cells. J Ethnopharmacol 2015; 168: 50-60.
[http://dx.doi.org/10.1016/j.jep.2015.03.048] [PMID: 25839119]
[182]
Sreejith PS, Asha VV. Glycopentalone, a novel compound from Glycosmis pentaphylla (Retz.) Correa with potent anti-hepatocellular car-cinoma activity. J Ethnopharmacol 2015; 172: 38-43.
[http://dx.doi.org/10.1016/j.jep.2015.05.051] [PMID: 26068427]
[183]
Patil S, Kadam V, Ghosh R. In vitro antioxidant activity of methanolic extract of stem bark of Gmelina arborea Roxb. (Verbenaceae). Int J Pharm Tech Res 2009; 1(4): 1480-4.
[184]
Ghareeb MA, Shoeb HA, Madkour HM, Refahy LA, Mohamed MA, Saad AM. Antioxidant and cytotoxic activities of flavonoidal com-pounds from Gmelina arborea (Roxb.). Glob J Pharmacol 2014; 8(1): 87-97.
[185]
Attanayake AP, Jayatilaka KAPW, Pathirana C, Mudduwa LKB. Gmelina arborea Roxb. (Family: Verbenaceae) extract upregulates the β-cell regeneration in STZ induced. J Diabetic Rats 2016; 2016: 4513871.
[186]
Shoeb HA, Madkour HM, Refahy LA, Mohamed MA, Saad AM, Ghareeb MA. Antioxidant and cytotoxic activities of Gmelina arborea ROXB. leaves. J Pharm Res Int 2014; 125-44.
[187]
Youl EN, Nassouri S, Ilboudo S. Hypoglycemic and antihyperglycemic activities of the aqueous ethanolic extracts of Gymnema sylvestre (Retz.) R. Br. Ex Schult and Sclerocarya birrea (A RICH) HOCHST. Afr J Pharm Pharmacol 2020; 14(9): 339-46.
[http://dx.doi.org/10.5897/AJPP2020.5187]
[188]
Di Fabio G, Romanucci V, Di Marino C, Pisanti A, Zarrelli A. Gymnema sylvestre R. Br., an Indian medicinal herb: Traditional uses, chem-ical composition, and biological activity. Curr Pharm Biotechnol 2015; 16(6): 506-16.
[http://dx.doi.org/10.2174/138920101606150407112903] [PMID: 25860062]
[189]
Rao N, Menghani E. Screening of various extracts of Gymnema sylvestre (Retz.) R. Br. ex Schult. for antimicrobial activity. J Med Plants Res 2012; 6(26): 4343-6.
[190]
Mak YW, Chuah LO, Ahmad R, Bhat R. Antioxidant and antibacterial activities of hibiscus (Hibiscus rosa-sinensis L.) and Cassia (Senna bicapsularis L.) flower extracts. J King Saud Univ Sci 2013; 25(4): 275-82.
[http://dx.doi.org/10.1016/j.jksus.2012.12.003]
[191]
Sachdewa A, Nigam R, Khemani LD. Hypoglycemic effect of Hibiscus rosa sinensis L. leaf extract in glucose and streptozotocin induced hyperglycemic rats. Indian J Exp Biol 2001; 39(3): 284-6.
[PMID: 11495291]
[192]
Shivananda Nayak B, Sivachandra Raju S, Orette FA, Chalapathi Rao AV. Effects of Hibiscus rosa sinensis L. (Malvaceae) on wound heal-ing activity: A preclinical study in a Sprague Dawley rat. Int J Low Extrem Wounds 2007; 6(2): 76-81.
[http://dx.doi.org/10.1177/1534734607302840] [PMID: 17558005]
[193]
Saraf A, Quereshi S, Sharma K, Khan NA. Antimicrobial activity of Lantana camara L. J Exp Sci 2011; 10(3): 57-67.
[194]
Sonibare OO, Effiong I. Antibacterial activity and cytotoxicity of essential oil of Lantana camara L. leaves from Nigeria. Afr J Biotechnol 2008; 7(15): 2618-20.
[195]
Al-Snafi A. Chemical constituents and pharmacological activities of Lantana camara-A review. Asian J Pharm Clin Res 2019; 12912: 10-20.
[http://dx.doi.org/10.22159/ajpcr.2019.v12i12.35662]
[196]
Kalita S, Kumar G, Karthik L, Rao KVB. A review on medicinal properties of Lantana camara Linn. Res J Pharm Technol 2012; 5(6): 711-5.
[197]
Gidwani B, Bhargava S, Rao S, Majoomdar A, Pawar D, Alaspure R. Analgesic, anti–inflammatory and anti–hemorrhoidal activity of aqueous extract of Lantana camara Linn. Res J Pharm Technol 2009; 2(2): 378-81.
[198]
Misra N, Sharma M, Raj K, Dangi A, Srivastava S, Misra-Bhattacharya S. Chemical constituents and antifilarial activity of Lantana camara against human lymphatic filariid Brugia malayi and rodent filariid Acanthocheilonema viteae maintained in rodent hosts. Parasitol Res 2007; 100(3): 439-48.
[http://dx.doi.org/10.1007/s00436-006-0312-y] [PMID: 17061115]
[199]
Borade AS, Kale BN, Shete RV. A phytopharmacological review on Lawsonia inermis (Linn.). Int J Pharm Life Sci 2011; 2(1): 536-41.
[200]
Chaudhary G, Goyal S, Poonia P. Lawsonia inermis Linnaeus: A phytopharmacological review. Int J Pharm Sci Drug Res 2010; 2(2): 91-8.
[201]
Kamal M. Pharmacological activities of Lawsonia inermis Linn.: A review. Molecules 2010; 15(4): 2139-51.
[PMID: 20428033]
[202]
Badoni Semwal R, Semwal DK, Combrinck S, Cartwright-Jones C, Viljoen A. Lawsonia inermis L. (henna): Ethnobotanical, phytochemical and pharmacological aspects. J Ethnopharmacol 2014; 155(1): 80-103.
[http://dx.doi.org/10.1016/j.jep.2014.05.042] [PMID: 24886774]
[203]
Oliveira DM, Melo FG, Balogun SO, et al. Antibacterial mode of action of the hydroethanolic extract of Leonotis nepetifolia (L.) R. Br. involves bacterial membrane perturbations. J Ethnopharmacol 2015; 172: 356-63.
[http://dx.doi.org/10.1016/j.jep.2015.06.027] [PMID: 26102550]
[204]
Bhuvaneswari S, Balamurugan A, Vaishnavi S, Sugunan S, Meena S, Chandran M, et al. Studies on antibacterial, antioxidant, larvicidal, pesticidal activities and phytochemistry of Leonotis nepetifolia (Linn) R. Br. Inter J Adv Pharm Sci 2013; 4(2): 303-9.
[205]
Bhattamisra SK, Khanna VK, Agrawal AK, Singh PN, Singh SK. Antidepressant activity of standardised extract of Marsilea minuta Linn. J Ethnopharmacol 2008; 117(1): 51-7.
[http://dx.doi.org/10.1016/j.jep.2008.01.012] [PMID: 18299179]
[206]
Chakraborty R, De B, Devanna N, Sen S. Antitussive, expectorant activity of Marsilea minuta L., an Indian vegetable. J Adv Pharm Technol Res 2013; 4(1): 61-4.
[http://dx.doi.org/10.4103/2231-4040.107502] [PMID: 23662283]
[207]
Tiwari OP, Bhattamisra SK, Tripathi PK, Singh PN. Anti-aggressive activity of a standardized extract of Marsilea minuta Linn. in rodent models of aggression. Biosci Trends 2010; 4(4): 190-4.
[PMID: 20811139]
[208]
Azmi L, Singh MK, Akhtar AK. Pharmacological and biological overview on Mimosa pudica Linn. Int J Pharm Life Sci 2011; 2(11): 1226-34.
[209]
Duyu T, Khatib N, Khanal P, Patil B, Hullatti K. Network pharmacology-based prediction and experimental validation of Mimosa pudica for Alzheimer’s disease. J Phytopharmacol 2020; 9(1): 46-53.
[http://dx.doi.org/10.31254/phyto.2020.9108]
[210]
Kokane DD, More RY, Kale MB, Nehete MN, Mehendale PC, Gadgoli CH. Evaluation of wound healing activity of root of Mimosa pudica. J Ethnopharmacol 2009; 124(2): 311-5.
[http://dx.doi.org/10.1016/j.jep.2009.04.038] [PMID: 19397984]
[211]
Ganguly M, Devi N, Mahanta R, Borthakur MK. Effect of Mimosa pudica root extract on vaginal estrous and serum hormones for screen-ing of antifertility activity in albino mice. Contraception 2007; 76(6): 482-5.
[http://dx.doi.org/10.1016/j.contraception.2007.08.008] [PMID: 18061708]
[212]
Nazeema T, Brindha V. Antihepatotoxic and antioxidant defense potential of Mimosa pudica. Int J Drug Discov 2009; 1(2): 1-4.
[http://dx.doi.org/10.9735/0975-4423.1.2.1-4]
[213]
Pawaskar S, Kale K. Antibacterial activity of successive extracts of Mimosa pudica. Indian Drugs-Bombay 2006; 43(6): 476.
[214]
Mahanta M, Mukherjee AK. Neutralisation of lethality, myotoxicity and toxic enzymes of Naja kaouthia venom by Mimosa pudica root extracts. J Ethnopharmacol 2001; 75(1): 55-60.
[http://dx.doi.org/10.1016/S0378-8741(00)00373-1] [PMID: 11282444]
[215]
Gami B, Pathak S, Parabia M. Ethnobotanical, phytochemical and pharmacological review of Mimusops elengi Linn. Asian Pac J Trop Biomed 2012; 2(9): 743-8.
[http://dx.doi.org/10.1016/S2221-1691(12)60221-4] [PMID: 23570006]
[216]
Baliga MS, Pai RJ, Bhat HP, Palatty PL, Boloor R. Chemistry and medicinal properties of the Bakul (Mimusops elengi Linn): A review. Food Res Int 2011; 44(7): 1823-9.
[http://dx.doi.org/10.1016/j.foodres.2011.01.063]
[217]
Roqaiya M, Begum W, Jahan D. A review on pharmacological property of Mimusops elengi Linn. Int J Herb Med 2015; 2(6): 24-30.
[218]
Saqib F, Ahmed MG, Janbaz KH, Dewanjee S, Jaafar HZ, Zia-Ul-Haq M. Validation of ethnopharmacological uses of Murraya paniculata in disorders of diarrhea, asthma and hypertension. BMC Complement Altern Med 2015; 15(1): 319.
[http://dx.doi.org/10.1186/s12906-015-0837-7] [PMID: 26354022]
[219]
Sayar K, Paydar M, Pingguan-Murphy B. Pharmacological properties and chemical constituents of Murraya paniculata (L.) Jack. Med Aromat Plants 2014; 3(4): 1-6.
[http://dx.doi.org/10.4172/2167-0412.1000173]
[220]
Selvi MT, Thirugnanasampandan R, Sundarammal S. Antioxidant and cytotoxic activities of essential oil of Ocimum canum Sims. from India. J Saudi Chem Soc 2015; 19(1): 97-100.
[http://dx.doi.org/10.1016/j.jscs.2011.12.026]
[221]
Nascimento JC, Barbosa LC, Paula VF, et al. Chemical composition and antimicrobial activity of essential oils of Ocimum canum Sims. and Ocimum selloi Benth. An Acad Bras Cienc 2011; 83(3): 787-99.
[222]
Bassole I, Nebie R, Savadogo A, Ouattara C, Barro N, Traore S. Composition and antimicrobial activities of the leaf and flower essential oils of Lippia chevalieri and Ocimum canum from Burkina Faso. Afr J Biotechnol 2005; 4(10): 1156-60.
[223]
Palungwachira P, Tancharoen S, Phruksaniyom C, et al. Antioxidant and anti-inflammatory properties of anthocyanins extracted from Oryza sativa L. in primary dermal fibroblasts. Oxid Med Cell Longev 2019; 2019: 2089817.
[224]
Ampawong S, Kengkoom K, Sukphopetch P, et al. Evaluating the effect of rice (Oryza sativa L.: SRNC05053-6-2) crude extract on psoria-sis using in vitro and in vivo models. Sci Rep 2020; 10(1): 17618.
[http://dx.doi.org/10.1038/s41598-020-74634-4] [PMID: 33077734]
[225]
de Moraes M, Bezerra M, Bezerra F, et al. Safety evaluation of Elixir Paregorico in healthy volunteers: A phase I study. Hum Exp Toxicol 2008; 27(10): 751-6.
[http://dx.doi.org/10.1177/0960327108090274] [PMID: 19042960]
[226]
Masihuddin M, Jafri M, Siddiqui A, Chaudhary S. Traditional uses, phytochemistry and pharmacological activities of Papaver somniferum with special reference of unani medicine an updated review. J Drug Deliv Ther 2018; 8(5-s): 110-4.
[http://dx.doi.org/10.22270/jddt.v8i5-s.2069]
[227]
Ahmed B, al-Howiriny TA, Mathew R. Antihepatotoxic activity of Phyllanthus fraternus. Pharmazie 2002; 57(12): 855-6.
[PMID: 12561252]
[228]
Koffuor G, Amoateng P. Antioxidant and anticoagulant properties of Phyllanthus fraternus GL Webster (Family: Euphorbiaceae). J Phar-macol Toxicol 2011; 6(7): 624-36.
[http://dx.doi.org/10.3923/jpt.2011.624.636]
[229]
Upadhyay R, Chaurasia JK, Tiwari KN, Singh K. Antioxidant property of aerial parts and root of Phyllanthus fraternus Webster, an im-portant medicinal plant. Sci World J 2014; 2014: 692392.
[230]
Saha A, Masud MA, Bachar SC, et al. The analgesic and anti-inflammatory activities of the extracts of Phyllanthus reticulatus. in mice model. Pharm Biol 2007; 45(5): 355-9.
[http://dx.doi.org/10.1080/13880200701212973]
[231]
Aarthi C, Babu P. Anti-cancer activity of Phyllanthus reticulatus on colon cancer cell line. Int J Civil Eng Technol 2017; 8: 943-7.
[232]
Sharma S, Kumar S. Phyllanthus reticulatus Poir an important medicinal plant: A review of its phytochemistry, traditional uses and phar-macological properties. Int J Pharm Sci Res 2013; 4(7): 2528-34.
[233]
Das BK, Shohel M, Pavel AM, et al. Anti hepatitis B viral activity of Phyllanthus reticulatus. Bangladesh Pharm J 2011; 14: 11-4.
[234]
Maruthappan V, Shree KS. A report on the antioxidant activity of the powder of the entire plant of Phyllanthus reticulatus Poir. Inter J Green Pharm 2010; 4(4): 265.
[http://dx.doi.org/10.4103/0973-8258.74136]
[235]
Katkar KV, Suthar AC, Chauhan VS. The chemistry, pharmacologic, and therapeutic applications of Polyalthia longifolia. Pharmacogn Rev 2010; 4(7): 62-8.
[http://dx.doi.org/10.4103/0973-7847.65329] [PMID: 22228943]
[236]
Lavanya C, Rao BG, Ramadevi D. Phytochemical and pharmacological studies on Polyalthia longifolia’. Int J Pharm Sci Res 2018; 3(4): 1-7.
[237]
Malairajan P, Gopalakrishnan G, Narasimhan S, Veni KJK. Evalution of anti-ulcer activity of Polyalthia longifolia (Sonn.) Thwaites in experimental animals. Indian J Pharmacol 2008; 40(3): 126-8.
[http://dx.doi.org/10.4103/0253-7613.42306] [PMID: 20040940]
[238]
Thenmozhi M, Rajeshwari S. Phytochemical analysis and antimicrobial activity of Polyalthia longifolia. Int J Pharm Bio Sci 2010; 1(3): 6288-99.
[239]
Lupoae P, Cristea V, Borda D, Lupoae M, Gurau G, Dinica RM. Phytochemical screening: Antioxidant and antibacterial properties of Po-tamogeton species in order to obtain valuable feed additives. J Oleo Sci 2015; 64(10): 1111-23.
[http://dx.doi.org/10.5650/jos.ess15023] [PMID: 26369590]
[240]
Toby A, Umoh O, Uyoh V, Umoden O. Evaluation of antidiarrhoeal activity of ethanolic extract of Pteridium aquilinum (L.) kuhn leaves on albino rats. World J Pharm Res 2020; 9(6): 294-305.
[241]
Gupta M. A review of pharmacological properties, pharmacognosy and therapeutic actions of Putranjiva roxburghii Wall.(Putranjiva). Int J Herb Med 2016; 4(6): 104-8.
[242]
Reanmongkol W, Noppapan T, Subhadhirasakul S. Antinociceptive, antipyretic, and anti-inflammatory activities of Putranjiva roxburghii Wall. leaf extract in experimental animals. J Nat Med 2009; 63(3): 290-6.
[http://dx.doi.org/10.1007/s11418-009-0336-6] [PMID: 19387768]
[243]
Garg AK, Chouhan P. Madanaphala (Randia dumetorum): A pharmacological and pharmacognostical review. Int J Recent Sci Res 2009; 10(04): 32061-4.
[244]
Ghosh D, Thejomoorthy P. Anti-inflammatory and analgesic activities of oleanolic acid 3-/3-glucoside (RDG-1) from Randia dumetorum (Rubiaceae). Indian J Pharmacol 1983; 15(4): 331.
[245]
Kandimalla R, Kalita S, Saikia B, et al. Antioxidant and hepatoprotective potentiality of Randia dumetorum Lam. Leaf and bark via inhibi-tion of oxidative stress and inflammatory cytokines. Front Pharmacol 2016; 7: 205.
[http://dx.doi.org/10.3389/fphar.2016.00205] [PMID: 27471465]
[246]
Patel Ritesh G, Pathak Nimish L, Rathod Jaimik D, et al. Phytopharmacological properties of Randia dumetorum as a potential medicinal tree: An overview. J Appl Pharm Sci 2011; 1(10): 24-6.
[247]
Prakash TD. Madanaphala (Randia dumetorum lam.): A phyto-pharmacological review. Int J Ayurvedic Med 2015; 6(2): 74-82.
[http://dx.doi.org/10.47552/ijam.v6i2.582]
[248]
Ribeiro PR, de Castro RD, Fernandez LG. Chemical constituents of the oilseed crop Ricinus communis and their pharmacological activities: A review. Ind Crops Prod 2016; 91: 358-76.
[http://dx.doi.org/10.1016/j.indcrop.2016.07.010]
[249]
Singh PP, Chauhan S. Activity guided isolation of antioxidants from the leaves of Ricinus communis L. Food Chem 2009; 114(3): 1069-72.
[http://dx.doi.org/10.1016/j.foodchem.2008.10.020]
[250]
Srikanth J, Muralidharan P. Evaluation of antioxidant properties of Sapindus emarginatus vahl. Asian J Exp Biol Sci 2010; 1(3): 693-9.
[251]
Vaghasiya Y, Nair R, Chanda S. Antibacterial evaluation of Sapindus emarginatus Vahl leaf in in-vitro conditions. Inter J Green Pharm 2009; 3(2): 165.
[http://dx.doi.org/10.4103/0973-8258.54913]
[252]
Duraipandiyan V, Kannan P, Ignacimuthu S. Antimicrobial activity of Sphaeranthus indicus L. Ethnobotanical leaflets 2009; 2009(3): 5.
[253]
Galani VJ, Patel BG, Rana DG. Sphaeranthus indicus Linn.: A phytopharmacological review. Int J Ayurveda Res 2010; 1(4): 247-53.
[http://dx.doi.org/10.4103/0974-7788.76790] [PMID: 21455454]
[254]
Upadhyay AK, Kumar K, Kumar A, Mishra HS. Tinospora cordifolia (Willd.) Hook. f. and Thoms. (Guduchi) - validation of the Ayurve-dic pharmacology through experimental and clinical studies. Int J Ayurveda Res 2010; 1(2): 112-21.
[http://dx.doi.org/10.4103/0974-7788.64405] [PMID: 20814526]
[255]
Sharma R, Amin H, Prajapati PK. Antidiabetic claims of Tinospora cordifolia (Willd.) Miers: Critical appraisal and role in therapy. Asian Pac J Trop Biomed 2015; 5(1): 68-78.
[http://dx.doi.org/10.1016/S2221-1691(15)30173-8]
[256]
Gupta R, Sharma A. Antifertility effect of Tinospora cordifolia (Willd.) s tem extract in male rats. 2003.
[257]
Beck S, Mathison H, Todorov T, Calderón-Juárez E-A, Kopp OR. A review of medicinal uses and pharmacological activities of Tridax procumbens (L.). J Plant Stud 2018; 7(1): 19-35.
[258]
Adjagba M, Awede B, Nondichao K, et al. Antihypertensive activity of different fractions of Tridax procumbens crude aqueous extract in wistar rats. J Phys Pharm Adv 2015; 5(9): 713-9.
[http://dx.doi.org/10.5455/jppa.20150917122209]
[259]
Manjamalai A, Valavil S, Grace V. Evaluation of essential oil of Trida x procumbens L. for anti-microbial and anti-inflammatory activity. Int J Pharm Pharm Sci 2012; 4(3): 356-63.
[260]
Asha KN, Chowdhury R, Hasan CM, Rashid MA. Antibacterial activity and cytotoxicity of extractives from Uvaria hamiltonii stem bark. Fitoterapia 2003; 74(1-2): 159-63.
[http://dx.doi.org/10.1016/S0367-326X(02)00323-4] [PMID: 12628415]
[261]
Lawrence NJ, Rennison D, McGown AT, Hadfield JA. The total synthesis of an aurone isolated from Uvaria hamiltonii: Aurones and flavones as anticancer agents. Bioorg Med Chem Lett 2003; 13(21): 3759-63.
[http://dx.doi.org/10.1016/j.bmcl.2003.07.003] [PMID: 14552774]
[262]
Parekh J, Chanda S. In vitro antibacterial activity of the crude methanol extract of Woodfordia fruticosa Kurz. Flower (Lythraceae). Braz J Microbiol 2007; 38(2): 204-7.
[http://dx.doi.org/10.1590/S1517-83822007000200004]
[263]
Baravalia Y, Vaghasiya Y, Chanda S. Brine shrimp cytotoxicity, anti-inflammatory and analgesic properties of Woodfordia fruticosa Kurz flowers. Iran J Pharm Res 2012; 11(3): 851-61.
[PMID: 24250512]

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