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Review Article

外泌体在不同类型疾病中的治疗应用：综述

卷 21, 期 2, 2021

发表于: 10 June, 2020

页: [87 - 95] 页: 9

弟呕挨: 10.2174/1566524020666200610164743

价格: $65

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摘要

外泌体是几乎所有细胞都分泌的纳米大小的囊泡，最近受到了广泛的关注。 除了它们在病理生理过程和诊断评估中的作用外，最近，一些研究还应用外泌体设计新的治疗应用。 外泌体可以衍生自多种细胞和组织，并基于来源，它们可以携带不同的天然成分，例如DNA，非编码小RNA，mRNA和蛋白质。 也可以通过添加所需的试剂（包括特定的生物分子或药物）来对它们进行工程改造。 两种形式都可以用于将其货物递送至靶细胞并理想地改变其功能。 本研究旨在对应用外泌体作为治疗不同类型疾病（包括癌症，心血管疾病，神经疾病，精神病学，肝脏和肾脏疾病）的治疗工具的各种研究提供全面的综述。

关键词: 外泌体，癌症，心血管疾病，神经系统疾病，肝脏疾病，肾脏疾病。

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