Review Article

姜黄素与石墨烯和碳纳米管的结合物:生物医学应用综述

卷 27, 期 40, 2020

页: [6849 - 6863] 页: 15

弟呕挨: 10.2174/0929867326666191113145745

价格: $65

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摘要

在过去的十年中,对于各种纳米生物技术应用,碳纳米管和石墨烯的使用一直在增长。由于它们的特殊特性,对碳同素异形体的这两种纳米结构进行了研究,以检测和治疗许多疾病。另一方面,姜黄素,一种著名的抗氧化剂和抗癌天然产物,正被广泛研究用于许多医学应用。有趣的是,许多报道显示姜黄素与碳纳米管或石墨烯的共轭物的巨大潜力。这些缀合物在经过适当设计并用生物分子功能化后,可以代表每种组分的宝贵特性,同时它们可以有效克服姜黄素和碳纳米材料(CNM)的不良溶解性问题。在这种情况下,姜黄素与CNM的结合物在生物传感应用中似乎非常有前途,并且据报道许多姜黄素对这些结合物的检测非常有效,尤其是许多生物分子的检测。同样,评估了使用功能化SWCNT递送姜黄素的负载和释放姜黄素,保护姜黄素免于降解和增强其溶解度的能力。提出了这些缀合物的其他性质仍待发现,生物学,医学,化学和材料工程学之间的跨学科方法将加速这些新型材料的应用。这篇综述旨在总结姜黄素CNM缀合物的应用发现。

关键词: 姜黄素,石墨烯,碳纳米材料,结合物,医学应用,纳米生物技术。

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