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Review Article

咪唑并[2,1-b]噻唑类药物的治疗多功能性的综述

卷 27, 期 40, 2020

页: [6864 - 6887] 页: 24

弟呕挨: 10.2174/0929867326666190729152440

价格: $65

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摘要

背景：咪唑并[2,1-b]噻唑，一种著名的稠合五元杂环，是药物化学领域最有前途和用途最广泛的部分之一。 已对咪唑并[2,1-b]噻唑的衍生物进行了研究，以开发具有多种药理活性的新衍生物。 该稠合的杂环也是许多治疗剂的一部分。 目的：综述咪唑并[2,1-b]噻唑衍生物及其在2000-2018年间开发的新分子的广泛药理活性及其实用性。 方法：对所有相关论文和专利进行了详尽的文献综述。 结论：本综述涵盖了多个方面，有望为基于咪唑并[2,1-b]噻唑的化合物的设计提供有用的见识，并会激发药物化学家获得全面且面向目标的信息，以实现这一目标。 在临床上可行的候选药物开发方面的重大突破。

关键词: 咪唑并[2

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