This 2-part reference informs readers about the application of drug delivery technologies to herbal medicines. Chapters cover a broad range of major topics on the subject of targeted drug delivery systems. These topics include the application of drug delivery systems for herbal nanomedicines, drug development issues, emerging technologies, adaptations for clinical use, market prospects and challenges of industrial commercialization. Chapters have been contributed by several experts in pharmaceutical chemistry and blend theoretical knowledge with practical aspects of drug delivery. Part I covers the following topics: - Introduction to nanotechnology and herbal-based nanoparticulate systems - Nucleic acid-based therapeutic drug delivery systems - Herbal bioactives: a booster dose for advanced pharmaceutical nanoscience - Pulmonary nano-drug delivery systems - Application of nano-drug delivery systems in improving the therapeutic efficacy of bioactive natural products - PEGylated liposomes - Insulin liposomes - Aquasomes: a promising novel drug carrier - Nanoparticle-aided herbal drugs: therapeutic implications on cholinergic dysfunction with relevance to Alzheimer's disease - Vitamins based nanomedicine approach - Recent advances in tumor targeting drug delivery systems: fundamentals of advanced pharmaceutical nanoscience - Niosomes: a revolutionary progress in the field of pharmaceutical sciences - Infectious diseases: pharmaceutical nanoscience for targeted drug delivery

This 2-part reference informs readers about the application of drug delivery technologies to herbal medicines. Chapters cover a broad range of major topics on the subject of targeted drug delivery systems. These topics include the application of drug delivery systems for herbal nanomedicines, drug development issues, emerging technologies, adaptations for clinical use, market prospects and challenges of industrial commercialization. Chapters have been contributed by several experts in pharmaceutical chemistry and blend theoretical knowledge with practical aspects of drug delivery. Part II covers the following topics: - Pharmaceutical nanosciences and their application in the delivery of various phytoconstituents - Design of cosmeceutical drug delivery systems: the role of nanotechnology in cosmeceuticals - Transfersomes: a novel vesicular transdermal delivery system - Self-nano/micro emulsified drug delivery systems - Phytosomes - The role of nanomedicines in ocular drug delivery systems - Colloidosomes as an efficient novel drug delivery system: an update - Herbal nanoscience: challenges and regulatory perspectives - Vitamins based nanomedicine approach - Dendrimers: a versatile nanoplatform for advanced targeting and bioactive(s) delivery - Targeted drug delivery systems for cells and cell organelles - Liposomes for herbal drug delivery - AI in pharmacy, herbal medicine and drug delivery: sci-fi or reality?

Frontiers in Natural Product Chemistry is a book series devoted to important advances in natural product chemistry. The series features volumes that cover all aspects of research in the chemistry and biochemistry of naturally occurring compounds, including research on natural substances derived from plants, microbes and animals. Reviews of structure elucidation, biological activity, organic and experimental synthesis of natural products as well as developments of new methods are also included in the series. Volume 10 of the series brings together 5 reviews on a variety of bioactive compounds. · An overview of cistus species growing in Sardinia: a source of bioactive compounds · Roles of natural abscisic acids in fruits during fruit development and under environmental stress · Progress in the research of naturally occurring biflavonoids: a look through · Plant metabolites for protecting human cells against radiation-associated damage: an integrative review · Chemical perspective and drawbacks in flavonoid estimation assays

The Chemistry inside Spices and Herbs: Research and Development brings comprehensive information about the chemistry of spices and herbs with a focus on recent research in this field. The book is an extensive 2-part collection of 20 chapters contributed by experts in phytochemistry with the aim to give the reader deep knowledge about phytochemical constituents in herbal plants and their benefits. The contents include reviews on the biochemistry and biotechnology of spices and herbs, herbal medicines, biologically active compounds and their role in therapeutics among other topics. Chapters which highlight natural drugs and their role in different diseases and special plants of clinical significance are also included. Part II continues from the previous part with chapters on the treatment of skin diseases and oral problems. This part focuses on clinically important herbs such as turmeric, fenugreek, ashwagandha (Indian winter cherry), basil, Terminalia chebula (black myrobalan). In terms of phytochemicals, this part presents chapters that cover resveratrol, piperine and circumin.

This textbook summarizes preliminary knowledge of bioactive molecules which serve as pharmaceuticals, their use, synthesis and mode of action, as well as the production of commercial constituents such as ethanol, citric acid, antibiotics, amino acid, and vitamins. The text is written mainly for the undergraduate and graduate levels of study of all Indian universities according to the recently implemented CBCS curriculum in a simple manner while keeping postgraduate course structures in view. Key Features: Simple structured layout suitable for learners - Considers the CBCS curriculum for Indian Institutions - Covers the subject in 2 parts (Part A: Pharmaceutical Chemistry, Part B: Production) - Covers several types of pharmaceuticals used in clinical practice - Covers the fermentation process and the production of antibiotics, pharmaceutical commodities, and nutrients - Includes an appendix for handy information

The Chemistry inside Spices & Herbs: Research and Development brings comprehensive information about the chemistry of spices and herbs with a focus on recent research in this field. The book is an extensive 2-part collection of 20 chapters contributed by experts in phytochemistry with the aim to give the reader deep knowledge about phytochemical constituents in herbal plants and their benefits. The contents include reviews on the biochemistry and biotechnology of spices and herbs, herbal medicines, biologically active compounds and their role in therapeutics among other topics. Chapters which highlight natural drugs and their role in different diseases and special plants of clinical significance are also included. Part I focuses on the general aspects of spice biotechnology, structure activity relationships and the natural products that can be used to treat different diseases - such as neurological diseases, inflammation, pain and infections. This part also covers information about phenolic compounds, flavonoids and turmeric supplements. This book is an ideal resource for scholars (in life sciences, phytomedicine and natural product chemistry) and general readers who want to understand the importance of herbs, spices and traditional medicine in pharmaceutical and clinical research.

This book details all the intricacies and essential knowledge involved in the research and development of the Coronil Kit - a combination of 3 ayurvedic medications for the common cold. It informs the reader about the huge potential of herbal drugs in fighting against any type of disease through evidence-based data from clinical trials and experiments. The book elaborates how current scientific techniques can be applied to understand the healing capacities of plants at their molecular level and thus utilize their different combinations to treat diseases by targeting harmful micro-organisms and simultaneously boosting the immune system. It covers methods of virtual screening and computational validation of identified phytochemicals as potential antiviral agents against the SARS-CoV-2 virus. 70 colored figures. Key Features: 1. Covers the molecular etiology of COVID-19 virus, 2. Covers guidance on drug formulation, hazard assessment, and clinical trials based on approved methods by regulatory organizations 3. Covers pharmacological, toxicological, and technically verified chemical composition of medicinal plants 4. Includes information about in vivo experiments and analysis of Humanoid Zebrafish trials 5. Includes methods of identifying antiviral agents against the SARS-CoV-2 virus 6. Includes chemical, analytical and technical studies of Coronil 7. Includes 70 images 7 chapters 8. Includes a bibliography and appendix The book is primarily intended as a primary resource for medical research scholars and researchers in pharmaceutical companies and as a secondary resource for B.A.M.S. students, medical postgraduate students, and Ayurveda enthusiasts.

This reference summarizes information about pharmaceuticals that can target infectious strains of coronaviruses to neutralize infections. Chapters focus on SARS-CoV-2, drug discovery methods and natural methods to combat the virus, which is a causative agent of COVID-19. Specifically, the book presents 5 chapters written by expert scholar on the following topics: Structure-Based Drug Discovery Approaches Applied to SARS-CoV-2 (the causative agent COVID- 19) Potential Antiviral Medicinal Plants against Novel SARS-CoV-2 Infections Caused by SARS Coronaviruses: Main Characteristics, Targets and Inhibitors Natural Sourced Traditional Indian and Chinese Medicines to Combat COVID- 19 Peptidomimetic and Peptide-Derived Agents Against 3CLpro from Coronaviruses The book contents present both conventional drug design and traditional approaches to discovering relevant drugs in an easy-to-read approach, which is supplemented by bibliographic references. It is intended as a reference for students (pharmacology, pharmacy) and researchers (virology) who are seeking information about antiviral drugs that can be used against coronaviruses.

Chemistry of Bipyrazoles: Synthesis and Applications covers the synthetic pathways for all types of bipyrazoles. 5 chapters cover bipyrazole systems, N,N- and N,C-bipyrazoles, namely 1,1`-bipyrazole, 1,3`-bipyrazole, 1,4`-bipyrazole, 3,3`-bipyrazoles, 3,4`-bipyrazoles and 4,4`-bipyrazoles The contents explain several types of reactions: 1) condensation reactions of hydrazines with tetracarbonyls, dihydroxydicarbonyl compounds or pyrazole-based difunctional compounds; 2) 1,3-dipolar cycloaddition of pyrazole-based hydrazonoyl halides with activated methylene compounds; 3) metal catalyzed cross-coupling reactions. The book concludes with a chapter that details the applications of bipyrazole derivatives in different industries. Information about advanced concepts used in chemical engineering such as metal-organic frameworks (MOFs) and corrosion inhibition are highlighted. The book contents are presented in an easy-to-understand manner suitable for readers in organic chemistry at senior levels of education and industry expertise. Each chapter is supplemented with detailed references.

Frontiers in Cardiovascular Drug Discovery is a book series devoted to publishing the latest advances in cardiovascular drug design and discovery. Each volume brings reviews on the biochemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships of molecules used in cardiovascular therapy. The book series should prove to be of great interest to all medicinal chemists and pharmaceutical scientists involved in preclinical and clinical research in cardiology. Volume 6 covers the following topics: - Cardiovascular effects of ranolazine and the scope for translational research: a current review of literature - Rho/Rho kinase signaling pathway and disease: - Hibernation or transformation? Challenges in cardiovascular drug development - New approaches in P2Y12 receptor blocker drugs use - Pathophysiological links between diabetes and cardiovascular diseases: at the biochemical and molecular levels