In this third year of the SARS-CoV-2 pandemic responsible for COVD-19 and related diseases worldwide, the scientific studies and reviews focused on this virus and its variants are still crucial. The third volume of the Coronaviruses series brings together some essential data regarding the origin, pathology and chemotherapeutic drugs to treat coronavirus infections. Contributions are written by experienced researchers with the goal of updating medical researchers and clinicians dealing with COVID-19 patients. It presents seven chapters covering a range of topics: (1) bat coronaviruses in the world, (2) hospital challenges during the COVID-19 pandemic, (3) the pro-inflammatory and thrombotic manifestations and the therapeutic options of Covid-19, (4) the common and rare dermatologic manifestations registered in COVID-19 patients, (5) the circulating biomarkers of cardiopulmonary disturbances in COVID-19, and (6) the aspects of pathology and pathogenesis of coronavirus infection

Degenerative nerve diseases are age-related, progressive and cause irreversible neurological loss that may lead to death. Chronic diseases like amyotrophic lateral sclerosis, Huntington's disease, Alzheimer's disease, and Parkinson's disease are associated with insoluble protein depositions and pose serious health challenges that may intensify in the coming decades. Current therapies only help to alleviate some of the physical or mental symptoms associated with neurodegenerative diseases, although there is currently no remedy for slow disease progression. In recent years, attempts have been made to discover a mechanism for neurodegenerative diseases and prospective treatment that may help mitigate aging effects and prevent these diseases. Natural products have been a constant source of new approaches for the treatment of neurodegenerative diseases, in particular plant alkaloids and polyphenolic compounds. Indopathy for Neuroprotection: Recent Advances highlights herbal treatments that are preferred over conventional treatments in some regions. Book chapters focus on the effects of various medicinal plants that have shown promise in reversing pathological symptoms of neurodegenerative disease and highlight the neuroprotective role of medicinal herbal phytochemicals and their mechanism of action. The book serves as a reference for pharmacology and herbal medicine scholars as well as healthcare workers interested in information about alternative and complementary therapies for neurological disorders.

Scientific Philosophy and Principles in Medicine is an accessible treatise on the philosophy that guides medical practice. It lays the foundation of a multidisciplinary framework behind the development of the medical profession. The book presents 10 chapters that cover issues that are frequently encountered by medical professionals in their career: philosophical and linguistic principles of rational thought, scientific, crisp and fuzzy logic, diagnostic aspects, the history of medicine, epistemological concepts, approximate reasoning, principles of medical wisdom, numerical and graphical diagnostics, and the collaboration of researchers involved in the fields of engineering and medicine. The author of the book brings several years of teaching experience and medical practice into this reference with the goal of integrating principles of scientific philosophy and logic into medical education. Readers will understand the process of devising rational diagnostic and treatment approaches that support human health as a generative process that seeks to solve problems through creativity, rather than a classical process of following medical protocols. This book is intended as a basic reference for medical students, teachers, and general readers interested in the application of logic, philosophy and scientific principles in medicine.

This handbook provides an introduction to COVID-19 and herbal medications that boost the human immune system against SARS-CoV-2. The topics are covered in 7 chapters starting with an introduction to the disease, followed by notes on nutraceuticals and common herbal medicines that have therapeutic potential by enhancing the patient's immune response. Special topics such as COVID-19 risk factors and Indian traditional medicines are also included to supplement the contents. The editors have taken advantage of the vast body of knowledge accumulated since the start of the COVID-19 pandemic in 2019. Chapters are written in simple language with structured headings to facilitate a quick understanding of the subject. References are provided for scholars interested in further readings. The book is a quick guide on immune boosting medicines for a broad audience that includes general medical practitioners, nurses, caregivers, and public healthcare workers involved in clinics working in local communities.

Type 2 diabetes (T2D) is a complex metabolic disorder characterized by impaired glucose metabolism and pancreatic β-cell dysfunction. No effective treatments are available for T2D, although there have been many developments in the therapeutic arena. Nitric oxide (NO) is an endocrine agent with multiple and important biological roles in most mammalian tissues. NO has emerged as a central regulator of energy metabolism and body composition. NO bioavailability is decreased in T2D. Several of the pharmaceuticals used in T2D affect the NO system and perhaps even more so by the drugs we use to treat diabetic cardiovascular complications. Experimental works in animal models of T2D show promising results with interventions aimed to increase NO signaling. However, translation into human studies has so far been less successful, but more large-scale prolonged studies are clearly needed to understand its role. This book is a collection of reviews that deal with the role of nitric oxide in type 2 diabetes, providing a unique overview of NO signaling, and pointing out key areas for more detailed research. The book includes contributions about the pathophysiology of T2D, a brief history of discovery and timeline of NO research, a comprehensive overview of impaired NO metabolism in T2D, precursors of NO (i.e., L-arginine, L-citrulline, nitrate, nitrites, and NO donors), NO and T2D from genetic points of view, NO and diabetic wound healing, NO and osteoporosis, NO and hyperuricemia, NO and Alzheimer's Disease, therapeutic applications of NO and NO donors in T2D. The compilation is of great value to anyone interested in the biochemistry of NO and its relationship to diabetes.

In recent years, we have witnessed significant advances in obstetric anesthesia, providing greater safety for the mother and the fetus, as well as an improvement in pain management procedures during labor. This volume presents updates in obstetrics and gynecology that are reflective of the changes in the demographics and associated clinical presentations of gynecological pathologies. It compiles state of the art information on the subject in 20 chapters contributed by more than 50 experts in obstetric anesthesia. The main objective of this volume is to inform and update readers about the different aspects essential to the practice of anesthesia and analgesia during pregnancy, labor, cesarean section and puerperium. The contents also include information about the management of pregnant women with different pathologies and high-risk pregnancies. The authors believe that it is essential for all anesthesiologists to be aware of the latest advances and well-contrasted scientific evidence that will allow them to carry out their usual clinical activity. The volume approaches the subject in a clear and didactic way for the benefit of all professionals involved in this field, including anesthesiologists, gynecologists, obstetricians, surgeons, clinicians and allied healthcare service providers.

Illustrated Pediatric Dentistry is intended to be a guide to undergraduate and postgraduate students in their understanding of pediatric dentistry. This textbook is modernized with the latest information and techniques in pediatric dentistry. The chapters cover primary pediatric dentistry, its clinical aspects, preventive dentistry, and information about the latest trends in the specialty. The text will equip readers with the knowledge suited to the changing environment of this vital domain. This textbook's editor has over forty-four years of teaching experience in pediatric dentistry and gives their broad perspective through the book content. This book is also the amalgamation of the thoughts of numerous subject experts of international repute. Part 1 of this book features information about the developmental psychology of a child, dental caries, craniofacial growth and development, growth of the maxilla and mandible, dentition and occlusion, and oral mucosa. Key Features: - The 15, structured chapters keep the latest trends of the subject in mind - The book content is illustrated with quality clinical images, - Chapters cover contemporary concepts of problems experienced when treating multiple dental disorders - The contributions exhibit distinct clinical expertise and the capability of imparting inimitable knowledge to budding professionals - The book includes modern and current state-of-the-art techniques used in the clinic - Topic outlines help to quickly review and easily locate content. Also, the Contents of the book are well structured and presented in a very lucid manner, making it easy to understand for students.

This book gives an overview of innovative approaches in telehealth and telemedicine. The Goal of the content is to inform readers about recent computer applications in e-health, including Internet of Things (IoT) and Internet of Medical Things (IoMT) technology. The 9 chapters will guide readers to determine the urgency to intervene in specific medical cases, and to assess risk to healthcare workers. The focus on telehealth along with telemedicine, encompasses a broader spectrum of remote healthcare services for the reader to understand. Chapters cover the following topics: - A COVID-19 care system for virus precaution, prevention, and treatment - The Internet of Things (IoT) in Telemedicine, - Artificial Intelligence for Remote Patient Monitoring systems - Machine Learning in Telemedicine - Convolutional Neural Networks for the detection and prediction of melanoma in skin lesions - COVID-19 virus contact tracing via mobile apps - IoT and Cloud convergence in healthcare - Lung cancer classification and detection using deep learning - Telemedicine in India This book will assist students, academics, and medical professionals in learning about cutting-edge telemedicine technologies. It will also inform beginner researchers in medicine about upcoming trends, problems, and future research paths in telehealth and telemedicine for infectious disease control and cancer diagnosis.

This reference summarizes recent advancements in knowledge about cardiovascular disease and pharmacology. The goal of the book is to inform readers about recent findings on cardiovascular therapeutics and how to conduct experiments to evaluate natural products. It presents 10 chapters that cover basic clinical research on cardiovascular diseases and therapeutic agents derived from natural sources. The book concludes with a series of experiments that demonstrate the methods to test the ameliorative effects of 3 phytochemicals: Biochanin A (red clover), Zingiberene (ginger oil) and Betaine (sugar beet). Key Features - 10 chapters that highlight recent research cardiovascular medicine and pharmacology - Covers knowledge about basic cardiovascular physiology, congestive heart failure treatment and the treatment of heart inflammation. - Covers uses, benefits, and drawbacks of numerous rodent and non-rodent animal models for studying CVD - Updates readers about 21st-century CRISPR-cas9 technology and its uses in CVD. - Covers the significance of Indian Ayurvedic techniques on the cardiovascular system, - Covers information about nutraceuticals for CVD therapy - Includes experiments to evaluate 3 phytochemicals for the treatment of different heart diseases such as hypertension, obesity-cardiomyopathy and the mitigation of inflammatory cytokines in myocardial infarction. This book is an informative resource for cardiologists, and researchers working in the field of cardiovascular pharmacology. It also helps readers to understand the benefits of herbal medications that are commonly available for consumption in homes.

Research on young individuals and childbearing adults being treated for neoplasia has revealed a rising number of requests for treatments aimed to maintain the possibility to conceive. To answer such requests, it is important for medical professionals to consider the necessity to cure the woman, to preserve her fertility, to give information both on the effect of neoplasia and treatments on pregnancy. Patients have to be informed on the possible treatment alternatives that are less aggressive towards the reproductive function, but at the same time, give desirable results in terms of survival. Neoplasia and Fertility describes the state-of-the-art on fertility preservation in women affected by neoplasia. The 11 book chapters inform the reader with the goal of equipping them with the required information needed to present the condition and to discuss the possibility of conceiving, and how to manage patients after oncologic treatments at different stages of pregnancy. Key Features - Informs the reader about the relationship between gynecological cancer and fertility in women through 11 chapters - Describes a broad range of cancers and relevant treatment options for maintaining fertility - Explains the role of a 'Fertility Sparing Team' in clinics - Familiarizes the reader with the ethics behind oncology treatments with reference to female fertility - Describes fertility issues related to hereditary cancers in women - Includes references for further reading The book serves as an informative reference on the subject to medical doctors in the gynecology, obstetrics and midwife specialties, and nurses training the gynecological oncology. It will also be of interest to healthcare administrators involved in fertility and oncology clinics, as well as general practitioners in family medicine.