This reference presents information about models utilized in experimental medicine and pharmaceutical research and development for several human diseases. Written by experts in immunology, cancer biology and pharmacology, the book provides readers with handy notes and updated data on animal models that are critical to research planning and lab execution. The main feature of the book is a set of 12 structured chapters that focus on a specific disease such as cancer, infectious diseases, autism, autoimmune diseases, Alzheimer’s disease and anemia. The contributors have gathered information on a wide range of genetic and physiological animal models that are employed in research with comparative charts that highlight their main differences. The book also includes chapters for special topics like food allergies and dentistry. Additional features of the book are an explanation of disease mechanisms that give an easy understanding, notes for idiopathic models and specific clinical conditions, and a list of references for advanced readers. Animal Models In Experimental Medicine is essential reading for scholars, graduate students and senior researchers in life sciences and clinical medicine. It also serves as a resource for professionals involved in bench-to-bedside pharmaceutical projects.

Research Methodology and Project Management in Biotechnology is a vital resource addressing core concepts in the dynamic field of biotechnology. This comprehensive textbook focuses on research methodology, techniques, and project management, and provides essential knowledge for students and faculty in life sciences and allied disciplines. Key features of the book include learning objectives, self-assessments and exercises, and a simple presentation (using bullet points, tables, and figures) designed to assist comprehension and retention of key information. The book is split into 5 units with 12 focused chapters: Unit I: Molecular Biology Techniques Covers various techniques used in molecular biology, including nucleic acid isolation, DNA fragmentation, PCR, DNA sequencing, and more. Unit II: Scientific Communication and Literature Introduces the process of research writing. Unit III: Biotechnology Entrepreneurship and Marketing Covers the role of funding, intellectual property rights, and regulations. Unit IV: Genomics, Proteomics, and Bioinformatics Explores DNA sequencing strategies, gene expression analysis, and the role of bioinformatics in drug discovery. Unit V: Advanced Biotechnological Techniques Covers topics such as antisense technology, molecular cytogenetics, pharmacogenomics, next-generation DNA sequencing, and ethical considerations in science and technology. Unit VI: Medical Biotechnology Covers disease detection and diagnosis, genetic diseases, personalized medicine, nanotechnology, gene therapy, regenerative medicine, and the Human Genome Project. This textbook is suitable for courses aimed to enhance biotechnology project planning and execution skills and building a professional career path in biotechnology.

Recent Progress in Pharmaceutical Nanobiotechnology: A Medical Perspective offers a comprehensive exploration of the dynamic field of pharmaceutical nanobiotechnology, focusing on its medical applications. This edited reference serves as a valuable resource for researchers, students, and professionals in various disciplines (pharmacology, biotechnology, clinical medicine and nanotechnology) , providing insights into the latest advancements and practical implications of nanotechnology in the pharmaceutical sector. The book presents 14 edited and referenced chapters that cover several themes for readers. General Pharmaceutical Nanobiotechnology: Introduction to the interdisciplinary field Exploration of nanoscale materials for medical purposes Nanoparticle Development and Applications: Bioinspired Nanomedicines Lipid-Based Nanocarriers Metallic Nanoparticles and Their Applications Nanoparticle Targeting Strategies Nanomedicine-Based Therapies for Cancer Stem Cells Biotechnological Aspects: Biotechnological Significance of Exosomes Glycoconjugates: Biosynthesis and Functions Innovative Nanotherapies: Novel Nanotechnological Approaches for Glioblastoma Biocompatibility of Nanomedicines and Bio Corona Diagnostic and Sensing Applications: Role of Nanoparticular/Nano Vesicular Systems as Biosensors In Vitro Applications of Drug-Carrying Nanoparticles in Cell Culture Studies In Vivo Imaging Techniques: Bioluminescence and Fluorescence Imaging Precision Medicine: The Role of Nano and Biopharmaceutics in Precision Medicine

Chemical Fingerprints of Medicinal Plant- HPTLC Profiling gives an overview of the use of high-performance thin-layer chromatography (HPTLC) for profiling medicinal herbs. Starting with an introduction to HPTLC the book guides the reader through HPTLC instrumentation and laboratory application. Additional notes on the stationary HPTLC phases and hyphenating HTPLC with other analytical techniques are also provided. The book concludes with an exhaustive list of HPTLC fingerprints of many herbs that can be used in medicinal preparations. The book outlines a scientific approach to the identification and selection of herbs for preparing traditional medications. By reading this book, learners will be able to 1) understand the basics of HPTLC, 2) learn how to use the instruments for lab analysis and 3) quickly identify chemical fingerprints of important medicinal herbs. Key Features - A concise overview of HPTLC and associated techniques - A Step-by-step guide to performing HPTLC analysis - Full color illustrations - An exhaustive list of HPTLC fingerprints for 108 medicinal plants, with botanical names - An appendix of TLC solvent systems and reagents for different phytochemical compounds and secondary metabolites - Simple language for easy understanding - Detailed bibliography Chemical Fingerprints of Medicinal Plant- HPTLC Profiling is an essential handbook for scholars in analytical chemistry, plant science and traditional medicine who want to understand the application of HPTLC techniques for research and development in phytomedicine.

Medicinal Plants: Microbial Interactions, Molecular Techniques, and Therapeutic Trends is a comprehensive exploration of the fascinating world of medicinal plants, their therapeutic advancements, and the application of molecular techniques to unlock their full potential. This book is structured into three illuminating sections, each shedding light on different facets of this rapidly developing field. Section 1: Exploring Plant-Microbe Interactions Covers the relationship between microbes and plants, the historical context and the pivotal role of microbes in shaping the future of medicinal plants. Discover the diverse array of bacteria associated with these plants and grasp their significance in enhancing the medicinal value of plants. Section 2: Harnessing Molecular Techniques Covers cutting-edge molecular techniques such as genome editing and modern breeding methods to optimize the genetic traits of medicinal plants. By understanding these techniques, readers will learn how to enhance plant growth, yield and quality. Section 3: Nanotechnology for Therapeutic Enhancement Covers nanotechnology and its transformative impact on medicinal plants. The section highlights emerging nano-engineering technology that can revolutionize the therapeutic properties of these plants. Medicinal Plants: Microbial Interactions, Molecular Techniques, and Therapeutic Trends is a book for Interdisciplinary readers: students, scientists, academics, and industry professionals alike. Whether you're a student, scientist, academic, or industry professional, this book is your gateway to the evolving world of plant-based medicine.

Where Did They Come From? The Origins of South American Fauna offers a fascinating journey into the origins of South American flora and fauna. Exploring life on the continent before and after the breakup of Gondwana, it delves into how creatures arrived in South America, be it through drifting across oceans or traversing land bridges. From birds and reptiles to mammals and fish, this book provides a comprehensive compendium of biological diversity, discussing their origins and evolutionary paths. Readers will gain insights into the mechanisms of animal dispersal, evolution, and the impact of the Great Biotic Interchange. The book also lists references for further exploration of the subject. The book is structured into five parts: Building South America: Covers tectonic movements, climate changes, and breaching isolation. Shaping South America: Explores the landforms and diverse biomes across the continent. Vertebrates within South America: Discusses unique amphibians, reptiles, fish, mammals, and birds that evolved on the continent. Vertebrates immigrating to South America: Examines exotic reptiles, birds, and mammals that found their way to the continent. The author also lists the families of almost all genera of South American animals, while giving knowledge of their origins. Recent Arrivals - the Great Biotic Interchange: Explores the significant interchange of various species that occurred later. Ideal for students, biologists, and anyone curious about the natural world, this book is a captivating read that uncovers the incredible history of South American fauna and its evolutionary tapestry.

This monograph research presents research in applied biomathematics carried out by the author at the beginning of this millennium. Monte Carlo simulations have been widely used by computational biologists to understand stochastics of living systems in biological matter. This work demonstrates how Monte Carlo simulations can help us to understand the nucleic acid structure, biophysics and chemistry. The author presents research on methods to understand aspects of the molecular dynamics of nucleic acids, DNA melting, evolutionary genetics, protein folding of Crambin and DNA vitrification. The book consists of five chapters and an appendix on the theoretical investigation on 10-12 potential of Hydrogen-Hydrogen covalent bond. Some of the previous research published in İnternational Journal of Modern Physics C and Modern Physics Letters B is extended for additional insight. Readers will find simple computer algorithms for hard mathematical physics problems such as mesoscopic, fractals, percolation, Metropolis algorithm and Langevin dynamics – many of which are also crucial to understanding experimental results of computer-aided drug discovery and cryopreservation. The author has taken care to explain calculations in a clear manner. All simulations have been conducted using Fortran (f77).

This volume is a compilation of reviews on the industrial usage of soil microorganisms. The contents include 16 brief reviews on different soil microbe assisted industrial processes. Readers will be updated about recent applications of soil bacteria, fungi and algae in sectors such as agriculture, biotechnology, environmental management. The reviews also cover special topics like sustainable agriculture, biodiversity, ecology, and intellectual property rights of patented strains, giving a broad perspective on industrial applications of soil microbes. Volume 2 includes reviews on destructive microbes like Macrophomina Phaseolina, eco-friendly microbes like Beauveria Bassiana, the identification of fungi in the rhizosphere, the industrial application of Trichoderma, and other topics. The text is easy to understand for readers of all levels, with references provided for the benefit of advanced readers.

Molecular and Physiological Insights into Plant Stress Tolerance and Applications in Agriculture is an edited volume that presents research on plant stress responses at both molecular and physiological levels. Key Features: - Emphasizes the morphological and physiological reactions of plants and the underlying molecular mechanisms when faced with stress from environmental or pathogenic factors. - Explores microbial dynamics within the plant rhizosphere and the application of plant growth-promoting bacteria as biofertilizers and endophytes as biocontrol agents to enhance crop growth and productivity for sustainable agriculture. - Systematically summarizes molecular mechanisms in plant stress tolerance and discusses the current applications of biotechnology, nanotechnology, and precision breeding to obtain stress-tolerant crops, contributing to climate-smart agriculture and global food security. - Includes contributions and references from multidisciplinary experts in plant stress physiology, plant molecular biology, plant biotechnology, agronomy, agriculture, nanotechnology, and environmental science. The content of the book is aimed at addressing UN SDG goals 2, 12, and 15 to achieve zero hunger and responsible consumption and production, and to sustainable use of terrestrial ecosystems, respectively. This comprehensive resource is suitable for researchers, students, teachers, agriculturists, and readers in plant science, and allied disciplines.

This book explores the intricate world of livestock sciences and production through the lens of systems biology. Offering a comprehensive exploration of both fundamental and advanced aspects, it unearths the potential of systems biology in the realm of livestock. The book presents 13 edited chapters on cutting-edge knowledge about systems biology and omics technology, showcasing genomics, transcriptomics, proteomics, metabolomics, and more. It illuminates the role of systems biology in livestock and disease management. Readers will learn about power of technologies that merge computational biology, nanobiotechnology, artificial intelligence, and single-cell sequencing. Each chapter is written by scientific experts and includes references for further reading. The book covers 4 key themes: Introduction to Systems Biology in Livestock Science: Uncover the foundation of integrating systems biology with omics data for animal scientists. Multi-scale Modeling Techniques: Explore how multi-scale modeling is shaping the future of system biology. Livestock Viral Diseases: Gain insights into how systems biology is revolutionizing our understanding of livestock viral diseases. Single Cell RNA-Sequencing: Understand the potential of this advanced technique in studying livestock animals at a cellular level. This book is a timely resource for students and researchers, offering a pathway to comprehend the crucial role systems biology plays in sustainable livestock production and management.