Scientific literature on SARS-COV-2 viruses and its variants (especially variants of concern such as the ‘Delta variant’) and important cellular targets is crucial to help researchers, epidemiologists, virologists and clinicians around the globe to develop a new generation of safer and more effective vaccines, and other treatments to address COVID-19 disease. The accompanying damage to the many organs and tissues of SARS-Co-2-infected people also needs to be understood and researchers are using data to devise meaningful protocols for treating these symptoms. This second volume of Coronaviruses brings together more useful information about the prevention, vaccination, and chemotherapies for the potential treatment of coronavirus infections. The volume includes eight chapters: (1) Broad spectrum antivirals to combat COVID-19 The reality and challenges, (2) COVID-19: Preventive and protective control management strategies, (3) Plant-derived extracts and bioactive compounds against coronavirus progression: preventive effects, mechanistic aspects, and structures, (4) Gastroenteritis: symptoms and epidemiology of SARS-CoV-2, (5) The chronicles of coronavirus: A Chinese king who conquered the entire world, (6) Traditional medicine as a natural remedy in ARDS & COVID-19, (7) Molecular pathogenesis of human coronaviruses of the 21st century, (8) COVID-19, mental health and neuropathophysiology of pain related to temporomandibular disorder. The volume serves as a novel compilation of key data on SARS-CoV-2 and COVID-19 and represents a resource of the utmost value for all scholars studying SARS-CoV infections. It should also be of great interest to clinicians who may be facing an overwhelming number of individuals affected with COVID-19, with over 267 million global cases documented as of the first week of December 2021).

Nanomedicinal Approaches Towards Cardiovascular Disease summarizes information about nanotechnology that is used in the diagnosis and regenerative treatment of heart diseases. Chapters in this reference introduce the reader to the basics of cardiac nanomedicine and cardiac regeneration before moving to advanced topics such as nanomedicine in cardiovascular diagnosis, imaging and therapeutics. </P> Key Features </P> - 13 chapters that cover nanotechnological aspects of cardiovascular diseases, contributed by expert scholars </P> - Simple, reader-friendly text suitable for readers of all academic levels </P> - Covers introductory topics of nanomedicine regenerative medicine in cardiovascular disease, cardiovascular diagnosis and therapeutics </P> - Covers advanced topics such as cardiovascular nanotheranositics, cardiac reprogramming, biomimetics, drug delivery systems and smart nanomaterials </P> - Includes a chapter on ethical implications in cardiovascular nanomedicine </P> - Includes bibliographic references for each chapter </P> Nanomedicinal Approaches Towards Cardiovascular Disease is a simple. informative reference on cardiovascular nanomedicine for scholars, healthcare professionals and nanotechnology enthusiasts, alike, which provides holistic knowledge on the subject in a single volume.

Thalassemia is one of the most common genetic diseases in the world. It has a relatively higher incidence in Mediterranean and Middle Eastern countries and presents a major public health and social challenge. This monograph updates the reader on the dental and orofacial characteristics of thalassemia major in Arab populations. Since very few detailed studies on these topics among Arabs have been published, the monograph attempts to bridge the knowledge gap in this area. Clinical, radiographic and odontometric features of the typical thalassemia major patient are clearly described in this book. </P> Key Features </P> - Provides a ready reference for dental and orofacial features in thalassemia major including a review of appropriate dental care </P> - Covers the pathogenesis, systemic complications, morbidity and mortality, management, and prevention of thalassemia major. </P> - Provides guidelines for optimal dental care. </P> - Covers special topics such as epidemiology, consanguinity, hematologic diagnosis, genetic testing, literature review, diet and nutrition, cost of treatment, and prevention </P> - Includes colored photographs, radiographs, drawings, tables, and 2 plates to illustrate examples and information </P> - Provides references for further reading </P> This monograph is a handy reference for medical and dental students, and caregivers on the subject of clinical dentistry in thalassemia patients.

Influenza is one of the most ancient and intriguing diseases that has been accompanying our civilization for millennia. While mankind has successfully defeated many dangerous influenza infections in the last couple of centuries, influenza control remains a serious problem for public health. A number of influenza vaccines and antiviral compounds have been licensed in recent times. However, the influenza virus is still ahead of us, as it continues to persistently infect humans to this day. Influenza: A Century of Research shows how influenza virology has developed historically and the tremendous knowledge that has been uncovered in the study of influenza. In this monograph, the authors present a historical perspective on influenza, chronologically, with an emphasis on its virology. Chapters cover information about the isolation of the first influenza viruses, substrates, and models for studying influenza, structure, and life cycle of the influenza virus, mechanisms of attenuation and virulence. Chapters progress into the multidisciplinary aspects of influenza research such as influenza virus ecology and the evolutionary origin of epidemic and pandemic influenza viruses. A significant part of the book also covers the description of the prevention and treatment of influenza and reasons that have contributed to insufficient control for influenza. The questions of how the COVID-19 pandemic affects the circulation of seasonal respiratory viruses, and if we can eliminate this virus are also addressed. Influenza: A Century of Research is an informative source of information for a broad range of readers, academic or otherwise, who are interested in knowing more about the disease.

Frontiers in Clinical Drug Research &amp;amp;ndash; Anti infectives is a book series that brings updated reviews to readers interested in learning about advances in the development of pharmaceutical agents for the treatment of infectious diseases. The scope of the book series covers a range of topics including the chemistry, pharmacology, molecular biology and biochemistry of natural and synthetic drugs employed in the treatment of infectious diseases. Reviews in this series also include research on multi drug resistance and pre-clinical / clinical findings on novel antibiotics, vaccines, antifungal agents and antitubercular agents. Frontiers in Clinical Drug Research &amp;amp;ndash; Anti infectives is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in the field of anti infective drug discovery and epidemiology. &amp;amp;lt;/p&amp;amp;gt; The seventh volume of this series features these interesting reviews: &amp;amp;lt;/p&amp;amp;gt; - Nucleic acid and peptide aptamers as potential antiviral drugs &amp;amp;lt;/p&amp;amp;gt; - Host-directed, antibiotic-adjuvant combination, and antibiotic-antibiotic combinations for treating multidrug-resistant (mdr) gram-negative pathogens &amp;amp;lt;/p&amp;amp;gt; - Bioactive substances as anti-infective strategies against clostridioides difficile &amp;amp;lt;/p&amp;amp;gt; - Anti-toxoplasma drug discovery and natural products: a brief overview &amp;amp;lt;/p&amp;amp;gt; - Development of antimalarial and antileishmanial drugs from amazonian biodiversity

The coronavirus disease 2019 (COVID-19) outbreak has spread throughout the globe and much time has passed since it was declared as a pandemic by the World Health Organization (WHO). COVID-19: Diagnosis and Management provides clinicians and scholars all the information on this disease in 2 volumes. Readers will find a concise and visual reference for this viral disease and will be equipped with the knowledge to assess and manage Sar-Cov-2 infection cases in clinical settings. </p> This book is divided into two parts (I and II). Part I provides comprehensive information about 1) History of Coronaviruses, 2) Epidemiology of COVID-19, 3) Clinical presentation of this viral disease and 4) COVID-19 diagnosis. Part II covers broader topics about this communicable disease including 1) the prevention and treatment methodology, 2) mortality and long-term complications, 3) COVID-19 vaccines and future perspectives. </p> Key Features: </p> Covers all the aspects of COVID-19 making this a perfect textbook for virology and medical students. </p> Chapter wise description and segregation of topics from pathophysiology to diagnosis and management of COVID-19. </p> Six chapters in the first part which focus on clinical basics of COVID-19. </p> Six chapters in the second part which cover broader topics for practical infection control. </p> Multiple tables and figures which summarize and highlight important points. </p> Presents a summary of the current standards for the evaluation and diagnosis of COVID-19. </p> Features a detailed list of references, abbreviations, and symbols. </p> This book is an essential textbook reference for medical students, scientists (virologists, pulmonologists) and public health officials who are required to understand COVDI-19 diagnosis and management as part of their clinical training or professional work.

This handbook explains the application of nanoparticles in medical diagnosis and treatment. It is a ready reference on the subject, starting with the introduction to nanoparticles and progressing to synthetic procedures for nanotherapeutics, human disease diagnosis and nanocarrier-based drug delivery. The book also covers information about specific nanoparticle conjugates, in which nanoparticles are combined with drugs or nucleic acid strands (DNA, siRNAs, shRNAs, miRNAs) as well as topics of relevant to this field such as immunotherapy and vaccination development strategies. Each chapter also provides references for further reading. </p> A Comprehensive Guide to Nanoparticles in Medicine is an ideal resource for scholars in medicine, pharmacology and technology who require an understanding to some basic facets of nanoparticles.

The coronavirus disease 2019 (COVID-19) outbreak has spread throughout the globe and much time has passed since it was declared as a pandemic by the World Health Organization (WHO). COVID-19: Diagnosis and Management provides clinicians and scholars all the information on this disease in 2 volumes. Readers will find a concise and visual reference for this viral disease and will be equipped with the knowledge to assess and manage Sar-Cov-2 infection cases in clinical settings. </p> This book is divided into two parts (I and II). Part I provides comprehensive information about 1) History of Coronaviruses, 2) Epidemiology of COVID-19, 3) Clinical presentation of this viral disease and 4) COVID-19 diagnosis. Part II covers broader topics about this communicable disease including 1) the prevention and treatment methodology, 2) mortality and long-term complications, 3) COVID-19 vaccines and future perspectives. </p> Key Features: </p> Covers all the aspects of COVID-19 making this a perfect textbook for virology and medical students. </p> Chapter wise description and segregation of topics from pathophysiology to diagnosis and management of COVID-19. </p> Six chapters in the first part which focus on clinical basics of COVID-19. </p> Six chapters in the first part which cover broader topics for practical infection control. </p> Multiple tables and figures which summarize and highlight important points. </p> Presents a summary of the current standards for the evaluation and diagnosis of COVID-19. </p> Features a detailed list of references, abbreviations, and symbols. </p> This book is an essential textbook reference for medical students, scientists (virologists, pulmonologists) and public health officials who are required to understand COVDI-19 diagnosis and management as part of their clinical training or professional work.

Current and Future Application of Artificial Intelligence in Clinical Medicine presents updates on the application of machine learning and deep learning techniques in medical procedures. . Chapters in the volume have been written by outstanding contributors from cancer and computer science institutes with the goal of providing updated knowledge to the reader. Topics covered in the book include 1) Artificial Intelligence (AI) applications in cancer diagnosis and therapy, 2) Updates in AI applications in the medical industry, 3) the use of AI in studying the COVID-19 pandemic in China, 4) AI applications in clinical oncology (including AI-based mining for pulmonary nodules and the use of AI in understanding specific carcinomas), 5) AI in medical imaging. Each chapter presents information on related sub topics in a reader friendly format. </p> The combination of expert knowledge and multidisciplinary approaches highlighted in the book make it a valuable source of information for physicians and clinical researchers active in the field of cancer diagnosis and treatment (oncologists, oncologic surgeons, radiation oncologists, nuclear medicine physicians, and radiologists) and computer science scholars seeking to understand medical applications of artificial intelligence.

This book series brings updated reviews to readers interested in advances in the development of anti-infective drug design and discovery. The scope of the book series covers a range of topics including rational drug design and drug discovery, medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships. Frontiers in Anti-Infective Drug Discovery is a valuable resource for pharmaceutical scientists and post-graduate students seeking updated and critically important information for developing clinical trials and devising research plans in this field. The ninth volume of this series features 5 reviews that cover some aspects of clinical and pre-clinical antimicrobial drug development, with 2 chapters focusing on drugs to treat leishmaniasis and dengue fever, respectively. - Use of preclinical and early clinical data for accelerating antimicrobial drug development - Post-translational modifications: host defence mechanism, pathogenic weapon, and emerged target of anti-infective drugs - Scope and limitations on the potent antimicrobial activities of hydrazone derivatives - Current scenario of anti-leishmanial drugs and treatment - Dengue hemorrhagic fever: the potential repurposing drugs