Precision medicine is a disruptive innovation with a fast-evolving pace in the healthcare ecosystem. Precision medicine enables precise diagnosis and targeted treatment by considering individual variability in the abnormalities of causative genes and molecular drivers behind biochemical mechanisms. A vast amount of data created by advanced omics technologies is a foundation of precision medicine’s success, and the implications of the findings from these technologies can potentially improve clinical outcomes. Recent Advances in Molecular and Translational Medicine: Updates in Precision Medicine presents essential information of molecular and translational research in precision medicine, with a specific focus on pediatrics. This book provides an accessible introduction to omics technologies, gives a detailed explanation of bioinformatics workflows to interpret high-throughput omics profiles for molecular diagnosis, and collects some of the cutting-edge research for precise therapeutics. Contributions to the book have been provided by experts in biomedical engineering and clinical practice, thus, bringing an informed perspective to the reader on each topic. The book is a valuable resource for postgraduate students, researchers, data scientists and clinicians interested in precision medicine, as well as researchers in the field of genetics and pediatrics who are interested in understanding the role of precision medicine in clinical practice.

This book is a concise textbook of iatrogenic pathology. Chapters cover iatrogenesis relevant to a broad range of medical subspecialties (cardiology, gastroenterology, gynecology, neurology, endocrinology and much more). The book presents an introduction to iatrogenesis which is followed by chapter-wise descriptions of iatrogenic lesions (lesions due to adverse drug reactions, lesions occurring during diagnosis and consequences of various therapeutic interventions) of the organs and systems of the body. This textbook is a handy resource on iatrogenic pathology for medical students and working professionals (clinical and nursing staff) involved in a range of medical subspecialties

The Fertility Promise is a complete guide to the often emotional, expensive and confusing process of fertility treatment. The book offers clear explanations and advice to anyone undergoing fertility treatment (such as in vitro fertilization) or anyone seeking information about relevant treatment options. The information includes advice to both male and female patients, LGBT patients, IVF clinics, the IVF treatment process, the issues surrounding IVF 'add-ons', what it is really like to go through fertility treatment and what the future of IVF might look like. Covering every aspect of the topic, the book is an extremely important point of reference for all fertility patients as well as individuals who wish to broaden their perspective on fertility medicine and clinics. The Fertility Promise informs both general readers and empowers fertility patients who are looking for the correct treatment, enabling them to clearly understand the fertility treatment process and to ask appropriate and often revealing questions on the subject.

In rehabilitation medicine, the therapeutic application of vibration energy in specific clinical treatments and in sport rehabilitation is being affirmed by a growing number of medical professionals. Clinical applications of mechanical vibrations exist in a variety of forms: mechanical vibrations, ultrasound therapy, extracorporeal shock waves therapy and Extremely Low Frequency (ELF) magnetic field therapy, for example. Each mode of therapy has a specific mechanism of action, dose and indication. However, the enormous potential of vibrations as therapy (understood as ESWT, mechanical vibration, ultrasounds, ELF) have yet to be explored in depth in both the experimental and in the clinical setting. The Mechanical Vibration: Therapeutic Effects and Applications is a monograph that presents basic information about vibrational therapy and its clinical applications. Readers will find information about the mathematical, physical and biomolecular models that make the foundation of vibrational therapy, applied mechanical vibrations in different form (whole body, ultrasound and extracorporeal shock waves) as well as an update on vibrational therapy in general. This monograph is a useful resource for medical professionals and researchers seeking information about the basics of vibrational therapy.

This e-book provides a comprehensive overview of state of the art applications of biomolecular techniques that are currently used, or are in development in the field of microbiological diagnostics research. In this respect, the topics covered include, genomics, proteomics, immunologics, biosensors, microarrays and nano-culture technologies. The broad range of techniques covered by the book will be invaluable to readers from professions allied to (but not exclusive to) microbiology analysts and researchers, laboratory technicians, (medical) microbiologists, molecular biologists, analytical physicists, and physicians.

Menopause is a significant event in a woman’s life as is generally considered as an indicator for senescence in women. Evidence suggests that menopause results in many psychological and postmenopausal health problems, such as anxiety, osteoporosis, cardiovascular disease, metabolic disorder and others. Menopausal symptoms and associated disorders are of great importance for public health as they influence the quality of life of affected individuals. Therefore proper management of menopause will definitely contribute to healthy aging and the overall well-being of women. This e-book reviews recent progress in the research and management of menopause and associated health problems. It provides comprehensive coverage of both clinical aspects and basic research of menopause. Topics covered in this e-book include research findings about risk factors for complex medical conditions associated with menopause along with the treatment options for these conditions, with particular emphasis on hormone replacement therapy (HRT). These conditions include osteoporosis, dementia, cardiovascular diseases, obesity and diabetes mellitus. Subsequent chapters detail on common oncological malignancies post menopause. The e-book concludes with a review of HRT treatment including its advantages and disadvantages followed by a review on risk factors, causes and complications of premature menopause occurring in women before an age of 40 years. This e-book is a valuable guide for medical researchers and gynecological professionals with a focus on the pathophysiology and treatment of this medical condition.

Emerging Technologies in Women’s Health is the first of a series of books dedicated providing updates on rapid advances in new technologies in women’s healthcare for researchers and clinicians. This eBook explains techniques of performing minimally invasive robotic surgery in a concise manner. Each chapter is contributed by experts in advanced laparoscopic and robotic surgery and contains several useful line drawn illustrations and photographs. This eBook should be of interest to gynecologic surgeons, fellows and residents.

Pregnancy Disorders and Perinatal Outcomes offers readers insights into knowledge related to maternal habits or disorders that could affect fetal development and lead to disability later in childhood and adulthood. It contains chapters on the role of placenta, hormones, stress, nutrition, diabetes, hypertension, in vitro fertilization, obesity, immune systems and epigenetics in pregnancy well-being and perinatal outcomes. This ebook integrates both fundamental and clinical medicine and well as molecular and cell biology. It is written in a multidisciplinary context and would be a handy reference to a wide spectrum of readers including students, clinicians (obstetricians, neonatologists, pediatricians) and basic scientists in gynecology.

This ebook addresses the impact of prenatal exposure to alcohol, and Fetal Alcohol Spectrum Disorders (FASD). It presents a compilation of current research by leading experts in the field and serves as a guide to future directions in FASD research, interventions and treatment. The book includes a comprehensive compendium of our knowledge of the dangers of prenatal alcohol exposure and covers ways to screen and intervene with pregnant women, diagnosis and treatment to ameliorate the effects of prenatal alcohol exposure (through the lifespan), and other related issues, such as building a state infrastructure of health services and legislation. The ebook is intended as a textbook for graduate courses relevant to FASD.

This e-book discusses the molecular relationship between biological systems and risk factors for in-utero oxidative insults, maternal health and the impact on fetus at different critical developmental time windows (prenatal or even postnatal). Plausibly, prenatal and early postnatal periods are the most critical “windows” to oxidative stress programming insults. Pro-oxidative stress is a common feature of many conditions associated with adverse fetal growth and/or preterm birth, such as pre-eclampsia, diabetes, smoking, malnutrition or excessive nutrition, infection or inflammation. Oxidative stress insults may be directly linked to or associated with many genetic, nutritional and environmental risk factors that contribute to risks of adverse fetal growth or preterm birth. This e-book should be a valuable reference for medical researchers and working professionals interested in congenital defects.