Drug repurposing is a cost-effective method of discovering new treatments for diseases than traditional drug development methods. It involves virtual screening of chemical candidates with the aid of computational methods like molecular docking. Drug Repurposing against SARS-CoV2 focuses on current trends in drug repurposing against the novel coronavirus strains. The book aims to give readers an overview of drug repurposing against COVID-19 and various techniques involved in the process. The book consolidates available information on the pathophysiology, drug targets, and drug repurposing against COVID-19 into a single, convenient resource. Key features -An up-to-date compilation of the evidence that supports the drug repurposing for COVID-19. -How to use repurposing of available drugs for disease therapy. -Provides an improved understanding of pathophysiology and SARS-CoV2 viral entry pathways. - Provides references for further reading

The immune system is highly complex, it senses foreign invaders, thus protecting the body. The adaptive arm of the immune system confers long-term protection, whereas the innate immune system confers immediate protection. The immune system uses pattern recognition receptors that are able to sense the molecular patterns associated with pathogens. Toll-like receptors (TLRs) are important mediators of inflammatory pathways in the gut which play a major role in mediating the immune responses towards a wide variety of pathogen-derived ligands and link adaptive immunity with the innate immunity. This book covers the role of TLRs in several vector-borne Diseases. Starting with an introduction to these diseases, the book explains the different types of receptors involved in these diseases. The diseases are then covered in separate chapters, including: malaria, lymphatic filariasis, visceral leishmaniasis, dengue fever, chikungunya, West Nile fever, and Japanese encephalitis. The book is a handy reference for researchers and trainees involved in clinical medicine and infection control. It can also serve as supplementary reading material for Students undertaking courses in biotechnology, public health, entomology, immunology, epidemiology, and life sciences.

Cancer Genes is a comprehensive list of the most critical genes known to contribute to cancer imitation and progression. The book delves into their location on each chromosome, providing valuable insights into the mechanisms of cancer gene dysregulation and genetic mutations which provide cancer cells with an advantage during each stage of tumorigenesis. The reference will familiarize readers with the location of cancer genes and equip them with the necessary information to identify relevant gene expression targets for research aimed at preventing the disease. The book is divided into two volumes focusing on cancer-causing genes found in chromosome pairs 1-12 (volume 1), and chromosomes 13-23 (volume 2). A key features of the book is a detailed reference list for advanced readers. The compilation is therefore a quick and handy reference on cancer causing genes for researchers, medical professionals, and anyone interested in understanding the genetic basis of cancer.

Handbook for Dental Chair Side Assistants is a timely and comprehensive resource designed to educate the dental chair side assistant and dental nurses about dentistry. This unique practical handbook covers the basic sciences emergencies and clinical aspects of all dental specialties. The theoretical knowledge and background about dental anatomy, dental microbiology, oral pathology, dental materials, dental radiology, dental procedures, common drugs, problems and dental instruments in dental practice is explained in simple and clear terms. The contents have been designed to give an optimum balance between clinical skills and theoretical foundation of the subject. The book is divided into 2 parts. Part 1 covers basic sciences and includes a guide to working in dental clinics. Part 2 includes a guide to medical emergencies, and information for different dental specialty settings. Key Features - Lucid yet simple explanations for learners - Covers basic and practical tips for dental assistants and nurses - Provides information for all dental specialties - Includes notes on advanced technology in dentistry - Illustrative and easy to retain information with colorful clinical pictures flowcharts and tabular data - A comprehensive summary for every chapter The book is useful reading material for undergraduate dental students and trainees.

Blood Oxidant Ties: The Evolving Concepts in Myocardial Injury and Cardiovascular Disease is an update on the recent advances in the development of antioxidant-based therapies. It starts with an overview of the mechanisms underlying the genesis of oxidative stress, summarizing the link between oxidative stress and a number of cardiovascular conditions. This is followed by an explanation of how oxidative stress interacts with lipid metabolism and the placental environment. Three chapters on the role of antioxidant-based therapy for cardiovascular diseases round up the book. Key Features - Outlines several cell-signaling pathways that are modulated by the interplay between reducing and oxidizing agents (redox status) and gene expression in the cardiovascular disease process - Brings information about maternal programming environment in the placenta - Covers development of novel nanotechnology-based antioxidant delivery systems for effective drug delivery - Includes references for further reading The book is aimed at a broad readership of scientific and medical professionals involved in research on cardiovascular diseases, pathophysiology, pharmacy, pharmaceutical science and life sciences. It also serves as a reference for scholars who want to understand the complex biochemical mechanisms of antioxidant agents.

This concise yet comprehensive book provides conceptual knowledge about forensic odontology in medical, dental, allied and litigation purposes. Written by authors that are highly knowledgeable, experienced and well-established in the field, this handbook lucidly explains basic and advanced components of dental forensics, beginning with anatomical attributes of the tooth, age assessment, dental anomalies and moving ahead to DNA fingerprinting from dental pulp, disaster victim identification from dentures, bite marks and oral autobiography which is a pragmatic approach in identification. Key features: - Gives an insight into basic and advanced aspects necessary to become an expert practitioner in forensic dentistry with a focus on how to provide apt evidence and explanations - Brings out remedial measures for challenges in disaster victim identification which can prove to be very helpful in crisis management - Provides references for further reading This book is intended as a handbook for readers who require a basic exposure to forensic dentistry. It will benefit learners and working professionals in forensic medicine, clinical settings, legal review, litigation, disaster management and allied roles involved in the criminal justice system.

Cancer Genes is a comprehensive list of the most critical genes known to contribute to cancer imitation and progression. The book delves into their location on each chromosome, providing valuable insights into the mechanisms of cancer gene dysregulation and genetic mutations which provide cancer cells with an advantage during each stage of tumorigenesis. The reference will familiarize readers with the location of cancer genes and equip them with the necessary information to identify relevant gene expression targets for research aimed at preventing the disease. The book is divided into two volumes focusing on cancer-causing genes found in chromosome pairs 1-12 (volume 1), and chromosomes 13-23 (volume 2). A key features of the book is a detailed reference list for advanced readers. The compilation is therefore a quick and handy reference on cancer causing genes for researchers, medical professionals, and anyone interested in understanding the genetic basis of cancer.

While the world is grappling with the growing problem of antibiotic resistance, marine organisms offer a promising solution with their diverse repertoire of bioactive compounds. This thematic volume explores the untapped potential of marine organisms in the fight against microbial threats. The focus of the 17 featured chapters lies in highlighting the vast array of antimicrobial agents that can be found within marine environments. The chapters provide in-depth knowledge about the latest discoveries, advancements and future needs in antimicrobial research. Readers will learn about astonishing discoveries of natural compounds with remarkable antimicrobial properties and sources. The list of agents covered in the book includes synthetic derivatives, bioactive polysaccharides and marine viruses. The book also includes chapters that cover various stages of the antimicrobial drug development process, providing an overview of recent antimicrobial agents derived from marine organisms, preclinical studies and the identification of patented drugs sourced from the ocean. Furthermore, the book sheds light on the diverse applications of these marine-derived compounds, spanning the fields of medicine, agriculture, and industry. Professionals in the fields of microbiology, marine biology, pharmaceutical sciences, and drug development will gain valuable insights into the use of marine organisms as a source of antimicrobial agents.

Common Pediatric Diseases: Current Challenges provides an update on different diseases and problems that affect child and adolescent health. The book starts with a quick introduction to challenges in the field of pediatrics and child health. This is followed by chapters on the outcomes of sexting, the integrated care of children with neurodevelopmental disorders, the influence of non-genetic transgenerational inheritance on children and adolescents’ development and the approach to pediatric genetic epilepsy. Additional topics covered in the book include the medical and social outcomes of cardiac diseases along with a review on specific aspects of fetal and neonatal medicine (meconium-stained newborns, transient tachypnea of newborns and fetal tumors). The book also features a chapter on Autism Spectrum Disorder during infancy and its early symptoms. The concluding chapter covers medical futility controversies and end-of-life care.

Natural Products for Treatment of Skin and Soft Tissue Disorders presents a simple and straightforward exploration of the role medicinal plants play in treating a diverse range of skin-related disorders. With contributions from researchers worldwide, this book delves into the pathology of skin conditions such as eczema, superficial mycoses, acne, vitiligo, and skin ulcers, providing effective treatment protocols using natural remedies. It also addresses prevalent disorders like atopic dermatitis and skin infections in developing countries. Finally, the book sheds light on the rising concern of skin cancer and potential natural therapeutic approaches. Readers will be equipped with the knowledge to harness the power of natural medicines in their dermatology practice. This comprehensive resource serves as a handbook for medical residents, students and dermatologists, offering invaluable insights into the potential of medicinal plants for the treatment of skin and soft tissue disorders.