Abstract
The design of novel, safe, and effective drugs of natural origin is a
challenging issue. To screen and uncover the infinite world of antimicrobial agents
derived from secondary metabolites for drug discovery requires the integration of highthroughput technologies such as biology systems (bioinformatics) and omics
technologies. These technologies include genomics, metagenomics, transcriptomes,
proteomics, and metabolomics). In the present chapter, we focused on revisiting several
aspects of these technologies in order to emphasize their unprecedented contribution to
drug discovery. In addition, they represent a step forward in pharmacological and
clinical research.
Keywords: Anti-infective agents, Omic technologies, Drugs system biology, Secondary metabolites, Bioinformatics.