Abstract
Ovarian cancer, an aggressive epithelial cancer, remains a major cause of
cancer mortality worldwide among women, but it can be diagnosed at an early stage
also. Surgical removal of ovarian tumour is a good option for the initial treatment, but
this is suitable only at the early stage of cancer. Surgery and other therapies like
chemotherapy, hormone role therapy and immunotherapy alone are insufficient for the
treatment of today’s advanced ovarian cancer. The aim of this book chapter is to review
the use of nano-particles in the treatment of ovarian cancer, along with surgery. It is
believed that nano therapies have lots of advantages like they stabilize drugs in our
body, deliver and penetrate the drugs to tumour-specific cells and can profile the
toxicity of chemotherapy. This book chapter also covers the development of
nanotherapies, types of nanocarriers and their role in ovarian cancer diagnosis and
treatment.
Keywords: Apoptosis, Biomarker, Chemotherapy, Detoxification, Drug cargo, DNA repair, Drug resistance, Graft rejection, Gynaecological cancer, Heterogeneous nature, Hydrophilic corona, Intracellular delivery, M alignancy, Metastatic tumour, Nanocarriers, Nanomaterial, Nanotechnology, Nano transmitter, Photodynamic therapy, Prophylactic, Photo thermal therapy, Renal clearance, Silent Killer, Systematic toxicity.
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