Abstract
Histopathology involves the study of tissue samples using a microscope to
understand the normal and abnormal contents of a given sample. Normal histology of
colorectal areas, such as mucosa and muscular, is greatly altered during the
development of cancer. Colorectal cancer can be divided into various grades during the
histopathological examination of tissues, which shows the extent of invasion of tumour
into the colon. This examination can also be used to understand the type of carcinoma
in the colon. Many factors affect this histopathological study and many drawbacks can
occur in grading systems that need to be improved.
Keywords: Alterations, Grading, Histopathology, Normal histology, Variant.
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