Neuropsychiatric Systemic Lupus Erythematosus (NP-SLE)

Neuropsychiatric systemic lupus erythematosus (NP-SLE) is one of the most

serious organ complications of SLE, affecting health, quality of life, and prognosis of

life in patients with SLE. Neurological symptoms are various. Among the pathological

conditions of SLE, those including neurologic syndromes of the central nervous

system, peripheral nervous system, and diffuse psychiatric and neuropsychiatric

syndrome are called NP-SLE in the American College of Rheumatology (ACR)

nomenclature. In NP-SLE, such a variety of pathophysiology should be considered

when selecting a treatment. In this article, we describe the neurological lesions of SLE

with illustrations.

Keywords: Cerebral atrophy, Diffuse cerebral edema, Neuropsychiatric-SLE (NP-SLE), Posterior reversible encephalopathy syndrome, Systemic lupus erythematosus (SLE).

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DOI https://doi.org/10.2174/9789815050653122040011	Print ISSN 2468-6662
Publisher Name Bentham Science Publisher	Online ISSN 2468-6670

Systemic Lupus Erythematosus: A Systematic Approach to Arthritis of Rheumatic Diseases