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Voltammetry for Sensing Applications

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Voltammetric Application in Detection of Anticancer Drug

Author(s): Shankar Ashok Itagi, M. H. Chethana, P. Manikanta, S. Sandeep*, C. S. Karthik, A. S. Santhosh, K. S. Nithin, Kumara Swamy N. K. and P. Mallu

Pp: 306-324 (19)

DOI: 10.2174/9789815039719122010014

* (Excluding Mailing and Handling)

Abstract

From the past few years the development of electrochemical sensor has
gained more attention due to the fact that these methods have high sensetivity, less
expensive and easy to handle when compared to other conventional methods. Cancer is
one among the serious disease faced by the human race in the current era. Presently, It
is treated with various treatments like chemotherapy, surgery and radiotherapy. Since
the impressive growth of these prime treatments, ample of anticancer drugs have been
developed. Alongside in recent years, the synthesis of nanomaterials and their
application in medicinal (biomedical) field has gained quite a focus in the research
field. Due to smaller size, improved solubility. surface tailor ability, electrocatalytic
activity, sensible detection and multifunctionality the nanomaterials are found to
possess greater applications in the growing field of pharmaceutical research. The
present chapter gives the reprots on the electrochemical detection of various anticancer
drugs like Methotrexate (MTX), 5-Flourouracil, Doxorubicin and Etoposide.

Keywords: Anticancer drugs , Doxorubicin , Etoposide , Methotrexate , Nano materials , Voltammetric methods , 5-Flourouracil .

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