Immunotherapy of Sepsis

Sepsis is a clinical condition that occurs due to dysregulated fundamental

host reaction to an infection, resulting in organ dysfunction. Proinflammatory

mediators are related to indications watched early in patients with sepsis. In spite of

decades of investigation, the morbidity and mortality of sepsis stay exceptionally very

high. Regardless of the recognition of numerous prospective targets in the complex

immune response pathways, no specific immunotherapeutic medicines are at present

accessible. Presently, immunosuppression in sepsis is a subject matter of strong

research amongst various pre-clinical and clinical studies. In fact, an improved

consideration of a patient’s immune status on a constant basis will plausibly allow

focused immunotherapy. This book chapter provides an overview of the epidemiology,

etiology, pathogenesis of sepsis and gives an outline of the challenges in

immunotherapy for patients suffering from sepsis.

Keywords: Immunotherapy, Inflammatory, Sepsis, Septic shock.

Cite as

Drug Delivery Letters

Recent Advances in Anti-Infective Drug Discovery

Applied Drug Research, Clinical Trials and Regulatory Affairs

Current Bioactive Compounds

Current Drug Delivery

Current Drug Safety

Drug Metabolism and Bioanalysis Letters

Recent Advances in Drug Delivery and Formulation

Reviews on Recent Clinical Trials

Current Drug Targets - Inflammation & Allergy

A Comprehensive Text Book on Self-emulsifying Drug Delivery Systems

Angiogenesis & Therapeutic Targets In Cancer

Anti-Angiogenesis Drug Discovery and Development

Biopolymers In Drug Delivery: Recent Advances and Challenges

Chemoinformatics: Directions Toward Combating Neglected Diseases

Current Advances in Drug Delivery Through Fast Dissolving/Disintegrating Dosage Forms

DOI https://doi.org/10.2174/9789815036879122110007	Print ISSN 1574-0889
Publisher Name Bentham Science Publisher	Online ISSN 2212-1064

Frontiers in Drug Design and Discovery