Login Register Cart 0
Generic placeholder image

Current Medical Imaging

Editor-in-Chief

ISSN (Print): 1573-4056
ISSN (Online): 1875-6603

Back
Journal Home About Journal Editorial Board Journal Insight Current Issue Volumes/Issues
Subscribe
Research Article

The Value of Corpus Callosum Measurement in the Diagnosis of Cerebral Atrophy

Author(s): Zhao Ji-Ping*, Cui Chun-Xiao, Duan Chong-Feng, Niu Lei and Liu Xue-Jun

Volume 16, Issue 6, 2020

Page: [682 - 687] Pages: 6

DOI: 10.2174/1573405615666190724092047

Price: $65

conference banner
Abstract

Objective: The study aimed to investigate the relationship between the corpus callosum area (CCa) and the degree of cerebral atrophy in patients with cerebral atrophy.

Methods: 119 patients with brain atrophy were grouped according to the degree of brain atrophy. Median sagittal CCa and intracranial area (ICa) were measured, and the ratio of corpus callosum to the intracranial area (CCa-ICa ratio) was calculated. The data were analyzed using ANOVA.

Results: CCa significantly reduced in patients with cerebral atrophy, and the degree of cerebral atrophy was found to be positively correlated with the degree of reduction in the CCa.

Conclusion: The reduction in the CCa and the CCa-ICa ratio in the median sagittal can be used as a reference indicator for the diagnosis and grading of brain atrophy in clinical practice.

Keywords: Corpus callosum, magnetic resonance imaging, cerebral atrophy, sagittal, brain, intracranial area.

Graphical Abstract

[1]
Aboitiz F, Montiel J. One hundred million years of interhemispheric communication: the history of the corpus callosum. Braz J Med Biol Res 2003; 36(4): 409-20.
[http://dx.doi.org/10.1590/S0100-879X2003000400002] [PMID: 12700818]
[2]
Funnell MG, Corballis PM, Gazzaniga MS. Cortical and subcortical interhemispheric interactions following partial and complete callosotomy. Arch Neurol 2000; 57(2): 185-9.
[http://dx.doi.org/10.1001/archneur.57.2.185] [PMID: 10681075]
[3]
Teipel SJ, Hampel H, Alexander GE, et al. Dissociation between corpus callosum atrophy and white matter pathology in Alzheimer’s disease. Neurology 1998; 51(5): 1381-5.
[http://dx.doi.org/10.1212/WNL.51.5.1381] [PMID: 9818864]
[4]
Sullivan EV, Pfefferbaum A, Adalsteinsson E, Swan GE, Carmelli D. Differential rates of regional brain change in callosal and ventricular size: a 4-year longitudinal MRI study of elderly men. Cereb Cortex 2002; 12(4): 438-45.
[http://dx.doi.org/10.1093/cercor/12.4.438] [PMID: 11884358]
[5]
Giedd JN, Blumenthal J, Jeffries NO, et al. Development of the human corpus callosum during childhood and adolescence: a longitudinal MRI study. Prog Neuropsychopharmacol Biol Psychiatry 1999; 23(4): 571-88.
[http://dx.doi.org/10.1016/S0278-5846(99)00017-2] [PMID: 10390717]
[6]
Wang PJ, Saykin AJ, Flashman LA, et al. Regionally specific atrophy of the corpus callosum in AD, MCI and cognitive complaints. Neurobiol Aging 2006; 27(11): 1613-7.
[http://dx.doi.org/10.1016/j.neurobiolaging.2005.09.035] [PMID: 16271806]
[7]
Lyoo IK, Satlin A, Lee CK, Renshaw PF. Regional atrophy of the corpus callosum in subjects with Alzheimer’s disease and multi-infarct dementia. Psychiatry Res 1997; 74(2): 63-72.
[http://dx.doi.org/10.1016/S0925-4927(97)00009-7] [PMID: 9204509]
[8]
Appenzeller S, Rondina JM, Li LM, Costallat LTL, Cendes F. Cerebral and corpus callosum atrophy in systemic lupus erythematosus. Arthritis Rheum 2005; 52(9): 2783-9.
[http://dx.doi.org/10.1002/art.21271] [PMID: 16142703]
[9]
Tomimoto H, Lin JX, Matsuo A, et al. Different mechanisms of corpus callosum atrophy in Alzheimer’s disease and vascular dementia. J Neurol 2004; 251(4): 398-406.
[http://dx.doi.org/10.1007/s00415-004-0330-6] [PMID: 15083283]
[10]
Paolillo A, Pozzilli C, Gasperini C, et al. Brain atrophy in relapsing-remitting multiple sclerosis: relationship with ‘black holes’, disease duration and clinical disability. J Neurol Sci 2000; 174(2): 85-91.
[http://dx.doi.org/10.1016/S0022-510X(00)00259-8] [PMID: 10727693]
[11]
Gonçalves LI, Dos Passos GR, Conzatti LP, et al. Correlation between the corpus callosum index and brain atrophy, lesion load, and cognitive dysfunction in multiple sclerosis. Mult Scler Relat Disord 2018; 20: 154-8.
[http://dx.doi.org/10.1016/j.msard.2018.01.015] [PMID: 29414290]
[12]
Xie S, Xiao JX, Wang W, et al. The relationship between atrophy and change of corpus callosum area in patients with cerebral vascular disease J Pract Radiol 2008; 24(1): 6-8.
[13]
Dietemann JL, Beigelman C, Rumbach L, et al. Multiple sclerosis and corpus callosum atrophy: relationship of MRI findings to clinical data. Neuroradiology 1988; 30(6): 478-80.
[http://dx.doi.org/10.1007/BF00339686] [PMID: 3226533]
[14]
Tomita H, Tone O, Ito U. Hemispheric cerebral atrophy after traumatic extra-axial hematoma in adults. Neurol Med Chir (Tokyo) 1997; 37(11): 819-24.
[http://dx.doi.org/10.2176/nmc.37.819] [PMID: 9414923]
[15]
Estruch R, Nicolás JM, Salamero M, et al. Atrophy of the corpus callosum in chronic alcoholism. J Neurol Sci 1997; 146(2): 145-51.
[http://dx.doi.org/10.1016/S0022-510X(96)00298-5] [PMID: 9077511]
[16]
Katsumata Y, Kawaguchi Y, Yamanaka H. Rapid progressive cerebral atrophy in systemic lupus erythematosus. J Rheumatol 2011; 38(12): 2689.
[http://dx.doi.org/10.3899/jrheum.110795] [PMID: 22134797]
[17]
Butler C, van Erp W, Bhaduri A, Hammers A, Heckemann R, Zeman A. Magnetic resonance volumetry reveals focal brain atrophy in transient epileptic amnesia. Epilepsy Behav 2013; 28(3): 363-9.
[http://dx.doi.org/10.1016/j.yebeh.2013.05.018] [PMID: 23832133]
[18]
Simpson E, Andronikou S, Vedajallam S, Chacko A, Thai NJ. Curved reformat of the paediatric brain MRI into a ‘flat-earth map’ - standardised method for demonstrating cortical surface atrophy resulting from hypoxic-ischaemic encephalopathy. Pediatr Radiol 2016; 46(10): 1482-8.
[http://dx.doi.org/10.1007/s00247-016-3638-3] [PMID: 27337989]
[19]
Jang JW, Park SY, Park YH, et al. A comprehensive visual rating scale of brain magnetic resonance imaging: application in elderly subjects with Alzheimer’s disease, mild cognitive impairment, and normal cognition. J Alzheimers Dis 2015; 44(3): 1023-34.
[http://dx.doi.org/10.3233/JAD-142088] [PMID: 25380589]
[20]
Li CF, Zhou KY. Preliminary study on computer automatic quantification of brain atrophy. Chinese J Radiol 2006; 40(6): 642-7.
[21]
Hansen TI, Brezova V, Eikenes L, Håberg A, Vangberg TR. How Does the Accuracy of Intracranial Volume Measurements Affect Normalized Brain Volumes? Sample Size Estimates Based on 966 Subjects from the HUNT MRI Cohort. AJNR Am J Neuroradiol 2015; 36(8): 1450-6.
[http://dx.doi.org/10.3174/ajnr.A4299] [PMID: 25857759]

Rights & Permissions Print Cite
Article Metrics
13
2
Wayfinder Image
© 2024 Bentham Science Publishers | Privacy Policy