摘要
结直肠癌是世界上第三大最常见的癌症。在过去十年中,转移性结直肠癌(mCRC)患者的生存率通过生物药物的引入得到了改善。然而,在这种新的和动态的治疗背景下,关于预后和可预测因素的研究对于指导肿瘤医师进行有效的治疗以及提高对结直肠癌生物学的理解是很重要的。它们的识别是一个密集的研究领域,我们未来的目标将是描绘肿瘤特异性的“分子标记”,以预测疾病的临床过程和最佳治疗。在本报告中,我们描述了临床、病理和分子生物标志物,它们可以作为mCRC的预后或预测因素。
关键词: 结直肠癌,转移,预后因素,预测因素,生物治疗,化疗。
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