Review Article

脂质纳米颗粒和活性天然化合物:制药应用的完美组合

卷 26, 期 24, 2019

页: [4681 - 4696] 页: 16

弟呕挨: 10.2174/0929867326666190614123835

价格: $65

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摘要

植物化学物质代表了一类重要的生物活性化合物,其特征是对健康有益。 尽管具有这些重要的特征,但是它们潜在的治疗特性却具有差的水溶性和膜渗透性,从而限制了它们在营养和药物应用中的应用。 脂质纳米颗粒是众所周知的具有高生物降解性和非凡生物相容性化学性质的载体系统,已成功地用作先进递送许多活性化合物(包括口服,局部和全身途径)的平台。 本文旨在回顾有关脂质纳米颗粒在活性天然化合物中的应用的最近十年的研究,报告这些胶体载体系统的实例和优点。

关键词: 固体脂质纳米颗粒,纳米结构脂质载体,活性天然化合物,药物递送,稳定性,载体系统

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