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Review Article

动脉粥样硬化和纳米医学的潜力：当前的进展和未来的机会。

卷 27, 期 21, 2020

页: [3534 - 3554] 页: 21

弟呕挨: 10.2174/0929867326666190301143952

价格: $65

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摘要

动脉粥样硬化是心血管疾病的主要诱因，是全球死亡的首位原因。它是一种与血脂异常和血管壁组成变化有关的动脉疾病。除了侵入性手术策略外，当前针对动脉粥样硬化的保守临床治疗分为两类，基于脂质调节的治疗和抗炎治疗。然而，基于常规药物递送系统的现有策略已经显示出对抗疾病发展的有限的功效和大量的副作用。纳米药物在靶向治疗，可控药物的递送和释放，新型特殊药物和诊断方式的设计以及具有多功能特征的生物相容性支架的开发中具有巨大潜力，这导致了动脉粥样硬化的诊断和治疗的发展。本文将重点介绍用于动脉粥样硬化诊断和治疗的最新纳米药物策略，并讨论在动脉粥样硬化进展过程中的潜在治疗靶标，这可为开发新型纳米平台抗动脉粥样硬化奠定基础。

关键词: 动脉粥样硬化，心血管疾病，纳米药物，药物输送系统，诊断，治疗，治疗学，支架。

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