Study the Effect of PG E1 and PGF2α on Male Rat Reproductive Functions

Title:Study the Effect of PG E1 and PGF2α on Male Rat Reproductive Functions

Volume: 18 Issue: 1

Author(s): Ali Esmail Al Snafi*, Khalid G. Al-Fartosi and Zainab Qasim Al-Yasiry

Affiliation:

• Department of Pharmacology, College of Medicine, University of Thi Qar, Nasiriyah,Iraq

Keywords: Reproduction, PGE1 , PGF2α, male, rats, LH, FSH, testosterone.

Abstract: Background: This research was performed to investigate the effects of prostaglandins on the sexual functions of albino male rats. The effects of prostaglandins on LH, FSH, testosterone secretion and semen quality of the male rats were investigated. PGE1 induced a significant decline in the level of LH, FSH and testosterone levels. PGE1 also induced significant decline in the testis, epididymal and seminal vesicle weights.

Conclusion: Furthermore, PGE1 caused significant reduction in sperm count, and significant decline in the viable and malformed sperm percent. However, PGF2α did not affect these parameters.

Cite this article as:

Al Snafi Ali Esmail *, Al-Fartosi G. Khalid and Al-Yasiry Qasim Zainab, Study the Effect of PG E1 and PGF2α on Male Rat Reproductive Functions, Immunology, Endocrine & Metabolic Agents in Medicinal Chemistry (Discontinued) 2018; 18 (1) . https://dx.doi.org/10.2174/1871522218666180417151333