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Current Protein & Peptide Science

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ISSN (Print): 1389-2037
ISSN (Online): 1875-5550

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Review Article

Antifungal Proteins with Antiproliferative Activity on Cancer Cells and HIV-1 Enzyme Inhibitory Activity from Medicinal Plants and Medicinal Fungi

Author(s): Jack Ho Wong, Tzi Bun Ng*, Hexiang Wang, Randy Chi Fai Cheung*, Charlene Cheuk Wing Ng, Xiuyun Ye, Jie Yang, Fang Liu, Chen Ling, Ki Chan, Xiujuan Ye and Wai Yee Chan*

Volume 20, Issue 3, 2019

Page: [265 - 276] Pages: 12

DOI: 10.2174/1389203719666180613085704

Price: $65

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Abstract

A variety of fungi, plants, and their different tissues are used in Traditional Chinese Medicine to improve health, and some of them are recommended for dietary therapy. Many of these plants and fungi contain antifungal proteins and peptides which suppress spore germination and hyphal growth in phytopathogenic fungi. The aim of this article is to review antifungal proteins produced by medicinal plants and fungi used in Chinese medicine which also possess anticancer and human immunodeficiency virus-1 (HIV-1) enzyme inhibitory activities.

Keywords: Antifungal proteins, anticancer, anti-HIV-1 enzymes, medicinal fungi, medicinal plants.

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