Abstract
Background: Progesterone is a sex steroid hormone. Since it has been discovered, it is widely used in the prevention of spontaneous preterm birth, hormone replacement therapy and other gynecological conditions.
Methods: We will review the progesterone preparations based on a comprehensive study of papers and patents from the traditional preparations up through the very recent literatures.
Results: This review mainly concentrates on oral, vaginal and micro delivery systems, involving different ways to prepare progesterone preparations.
Conclusion: Although progesterone has first-pass effects, with these methods, the bioavailability and compliance can be greatly increased.
Keywords: Delivery system, injection, microspheres, oral, progesterone preparations, vaginal.
Graphical Abstract
Call for Papers in Thematic Issues
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