摘要
哺乳动物的免疫系统是一个完美的防御系统，抛光了数亿年的演变。独特的灵活性和适应性已经为许多外来病原体创造了几乎难以逾越的障碍，这些病原体每一刻都在殴打我们。遗憾的是，仍然主要是神秘的触发器有时会说服免疫系统重新针对自身抗原。这场内战仍在进行之中，没有任何怜悯，也没有掳掠俘虏，最终导致人体不可逆转的病态变化。在过去二十年中出现的研究使我们有希望通过各种技术来“重置”免疫系统来克服自身免疫性疾病。在本报告中，我们总结了利用短多肽（主要是自身抗原的片段）治疗自身免疫性神经变性的最新进展。
关键词: 多发性硬化症，特异性变应原免疫治疗，耐受性，交叉反应性，自身反应性B细胞消除，自身抗体，免疫毒素，脂质体。
Call for Papers in Thematic Issues
Advances in Medicinal Chemistry: From Cancer to Chronic Diseases.
The broad spectrum of the issue will provide a comprehensive overview of emerging trends, novel therapeutic interventions, and translational insights that impact modern medicine. The primary focus will be diseases of global concern, including cancer, chronic pain, metabolic disorders, and autoimmune conditions, providing a broad overview of the advancements in ...read more
Approaches to the Treatment of Chronic Inflammation
Chronic inflammation is a hallmark of numerous diseases, significantly impacting global health. Although chronic inflammation is a hot topic, not much has been written about approaches to its treatment. This thematic issue aims to showcase the latest advancements in chronic inflammation treatment and foster discussion on future directions in this ...read more
Cellular and Molecular Mechanisms of Non-Infectious Inflammatory Diseases: Focus on Clinical Implications
The Special Issue covers the results of the studies on cellular and molecular mechanisms of non-infectious inflammatory diseases, in particular, autoimmune rheumatic diseases, atherosclerotic cardiovascular disease and other age-related disorders such as type II diabetes, cancer, neurodegenerative disorders, etc. Review and research articles as well as methodology papers that summarize ...read more
Chalcogen-modified nucleic acid analogues
Chalcogen-modified nucleosides, nucleotides and oligonucleotides have been of great interest to scientific research for many years. The replacement of oxygen in the nucleobase, sugar or phosphate backbone by chalcogen atoms (sulfur, selenium, tellurium) gives these biomolecules unique properties resulting from their altered physical and chemical properties. The continuing interest in ...read more
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Current Bioactive Compounds
Current Cancer Drug Targets
Combinatorial Chemistry & High Throughput Screening
Current Cancer Therapy Reviews
Current Diabetes Reviews
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