萜烯类物质对心血管系统的保护作用：现状与未来展望

Title:Protective Effects of Terpenes on the Cardiovascular System: Current Advances and Future Perspectives

Volume: 23 Issue: 40

Author(s): Jorge M. Alves-Silva, Monica Zuzarte, Carla Marques, Ligia Salgueiro, Henrique Girao

Affiliation:

关键词: 萜类，心血管，心脏病，低血压，血管舒张，构效关系

摘要: Background: Cardiovascular diseases (CVDs) are the leading cause of morbidity and mortality worldwide that seriously affect patient’s life quality and are responsible for huge economic and social burdens. It is widely accepted that a plant-based diet may reduce the risk of CVDs by attenuating several risk factors and/or modulating disease’s onset and progression. Plants are rich in secondary metabolites, being terpenes the most abundant and structurally diverse group. These compounds have shown broad therapeutic potential as antimicrobial, antiviral, anti-inflammatory and antitumor agents. Despite their popularity, scientific evidence on terpenes cardiovascular effects remains sparse, limiting their potential use as cardioprotective and/or cardiotherapeutic agents.

Cite this article as:

Jorge M. Alves-Silva, Monica Zuzarte, Carla Marques, Ligia Salgueiro, Henrique Girao , Protective Effects of Terpenes on the Cardiovascular System: Current Advances and Future Perspectives, Current Medicinal Chemistry 2016; 23 (40) . https://dx.doi.org/10.2174/0929867323666160907123559