Bioinspired Platform Conjugated Active Drug Delivery

doi:10.2174/1389450117666160602202850

摘要

背景：纳米技术和生物技术的迅速出现使得药物传递系统的革命性发展成为可能。近年来，给药引起了广泛的研究兴趣；应用于改善这些载体的功能及其应用。目的：主动给药是目前生物实体中靶向运输的理想途径，可以与治疗介质配合运输货物。结果与结论：综述了几种活性靶向给药模式，包括分子马达、生物伪装颗粒和自推进式NaN。omotors。随后介绍了一系列活性靶向药物载体，并讨论了它们的靶向结合能力。此外，主动靶向转运机制对港口进行了详细的阐述，并重点介绍了一些有前途的作品。

关键词: 生物激发，主动靶向，药物传递，分子马达，生物伪装，自推进纳米材料。

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Current Drug Targets

Title:Bioinspired Platform Conjugated Active Drug Delivery

Volume: 19 Issue: 4

关键词: 生物激发，主动靶向，药物传递，分子马达，生物伪装，自推进纳米材料。

摘要: Background: The rapid emergence of nanotechnology and biotechnology has enabled revolutionary developments for drug delivery systems. Recently, drug delivery has attracted extensive research interest; applied to improve the functions of these carriers and their applications.

Objective: Active drug delivery is currently approved as an ideal approach for targeted transport in a biological entity and can cooperate with therapeutic mediums in transporting cargoes.

Results and conclusion: In this review, several active targeted cargomediated drug delivery patterns have been summarized, including molecular motors, bio-camouflaged particles, and self-propelled nanomotors. Subsequently, a series of active targeted carriers for drug delivery were introduced, and their ability for targeted binding was discussed. Furthermore, the mechanism of active targeted transport was exposited in detail, and some promising works are highlighted.

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Bioinspired Platform Conjugated Active Drug Delivery, Current Drug Targets 2018; 19 (4) . https://dx.doi.org/10.2174/1389450117666160602202850

DOI https://dx.doi.org/10.2174/1389450117666160602202850	Print ISSN 1389-4501
Publisher Name Bentham Science Publisher	Online ISSN 1873-5592

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