Current Topics in Medicinal Chemistry
Title:Editorial (Thematic Issue: Alzheimer’s Disease - Mechanisms, Drug Targets and Alternative Treatments)
Volume: 16 Issue: 5
Author(s): Qian Hua and Rongqiao He
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Hua Qian and He Rongqiao, Editorial (Thematic Issue: Alzheimer’s Disease - Mechanisms, Drug Targets and Alternative Treatments), Current Topics in Medicinal Chemistry 2016; 16 (5) . https://dx.doi.org/10.2174/156802661605151022150458
DOI https://dx.doi.org/10.2174/156802661605151022150458 |
Print ISSN 1568-0266 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4294 |
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AlphaFold, a groundbreaking AI tool for protein structure prediction, is revolutionizing drug discovery. Its near-atomic accuracy unlocks new avenues for designing targeted drugs and performing efficient virtual screening. However, AlphaFold's static predictions lack the dynamic nature of proteins, crucial for understanding drug action. This is especially true for multi-domain proteins, ...read more
Artificial intelligence for Natural Products Discovery and Development
Our approach involves using computational methods to predict the potential therapeutic benefits of natural products by considering factors such as drug structure, targets, and interactions. We also employ multitarget analysis to understand the role of drug targets in disease pathways. We advocate for the use of artificial intelligence in predicting ...read more
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The use of several compounds has been the subject of increasing interest in phytochemistry, biochemistry, and other fields of research at the chemistry-biology-ecosystems interface. In spite of the continued search for new anticancer drugs, cancer remains a leading cause of death. Cancer mortalities are expected to increase to 12.9 million, ...read more
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