Predictive Factors of Febrile Neutropenia Induced by Anticancer Chemotherapy in the South of Tunisia

Title:Predictive Factors of Febrile Neutropenia Induced by Anticancer Chemotherapy in the South of Tunisia

Volume: 11 Issue: 1

Author(s): Afef Khanfir, Wala Ben Kridis, Safia Masmoudi, Senda Mezghani, Adnen Hammami and Mounir Frikha

Affiliation:

Keywords: Chemotherapy, febrile neutropenia, predictive factor.

Abstract: Introduction: Febrile Neutropenia (FN) secondary to chemotherapy is the most common and the earliest hematological complication. The aim of this work is to study the predictive factors of FN.

Materiel and Methods: This is a retrospective study including 186 episodes of FN induced by chemotherapy treated in the department of oncology at Sfax in southern Tunisia during the period between 1 January 2006 and 31 December 2010. Result: The mean age of patients was 40 years. One hundred and seventeen patients had solid tumors (86.02%), 18 patients (13.23%) had hematological malignancies and one patient was treated for hypo pharyngeal cancer and aplastic Anemia. Chemotherapy was indicated for curative purpose in 94 cases and palliative purpose in 92 cases. One hundred and four patients (76.5%) had a single episode of FN and 32 (23.5%) had at least two episodes. The average time of febrile neutropenia was 11 days.

Cite this article as:

Khanfir Afef, Kridis Ben Wala, Masmoudi Safia, Mezghani Senda, Hammami Adnen and Frikha Mounir, Predictive Factors of Febrile Neutropenia Induced by Anticancer Chemotherapy in the South of Tunisia, Reviews on Recent Clinical Trials 2016; 11 (1) . https://dx.doi.org/10.2174/1574887110666151021093549