Abstract
It is now very much clear that the microbiome plays an important part in human health. Microbiome is associated with several diseases and targeting the whole microbiome is certainly a challenge before the scientists. The “Human Microbiome Project” is continually exploring certain therapeutic targets inside microbiome landscape that could be utilized for the treatment of microbiome associated diseases. Additionally, associated research across the globe is going on and now some potential targets are available that might be beneficial for the designing and synthesis of novel drugs. In this review, we made an effort to discuss all the potential targets and corresponding possible drugs/treatments available for each of them. However, it is not possible to treat all microbiome associated diseases with a single drug/drug combination. Therefore, for different diseases, different treatments/drugs (whether xenobiotic or non-xenobiotic) could be used for better therapeutic efficacy.
Keywords: Bacteriocins, drug, microbiome, probiotics, traditional chinese medicines, vitamin D, xenobiotic.
Current Drug Metabolism
Title:Xenobiotic and Non-Xenobiotic Interventions in the Microbiome Therapeutics
Volume: 16 Issue: 4
Author(s): Vipin Kumar, Pradeep Kumar and Vikas Sharma
Affiliation:
Keywords: Bacteriocins, drug, microbiome, probiotics, traditional chinese medicines, vitamin D, xenobiotic.
Abstract: It is now very much clear that the microbiome plays an important part in human health. Microbiome is associated with several diseases and targeting the whole microbiome is certainly a challenge before the scientists. The “Human Microbiome Project” is continually exploring certain therapeutic targets inside microbiome landscape that could be utilized for the treatment of microbiome associated diseases. Additionally, associated research across the globe is going on and now some potential targets are available that might be beneficial for the designing and synthesis of novel drugs. In this review, we made an effort to discuss all the potential targets and corresponding possible drugs/treatments available for each of them. However, it is not possible to treat all microbiome associated diseases with a single drug/drug combination. Therefore, for different diseases, different treatments/drugs (whether xenobiotic or non-xenobiotic) could be used for better therapeutic efficacy.
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Cite this article as:
Kumar Vipin, Kumar Pradeep and Sharma Vikas, Xenobiotic and Non-Xenobiotic Interventions in the Microbiome Therapeutics, Current Drug Metabolism 2015; 16 (4) . https://dx.doi.org/10.2174/138920021604150902180008
DOI https://dx.doi.org/10.2174/138920021604150902180008 |
Print ISSN 1389-2002 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5453 |
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