摘要
纳米技术为显著提高许多致命性疾病(包括肺结核TB)的诊断提供了巨大可能性,在健康保障方面显示出了巨大的潜力。纳米药物使现代药物养生更有效地对抗疾病(特别是肺结核),并有着长效释放,半衰期延长,靶点药物浓度提高,毒性降低,副作用减少等特征。然而,疾病的严重性强烈要求(人们)研发更好的伴随养生疗法:使用纳米微粒诊断,治疗和管理病人。这篇综述为现代肺结核养生疗法指明了一些在纳米药物领域(特别是提供优秀选择性的药物分布领域)的相关疗法。这篇综述也强调了(人们)对具有高选择性,生物相容性,生物可降解性的纳米载体的需求。
关键词: 纳米药物,肺结核,药物,药物养生疗法
Current Drug Targets
Title:Nano-Based Anti-Tubercular Drug Delivery and Therapeutic Interventions in Tuberculosis
Volume: 18 Issue: 1
Author(s): Rohit Sharma, Amanpreet Kaur, A. K. Sharma, Neeraj Dilbaghi, Anil K. Sharma
Affiliation:
关键词: 纳米药物,肺结核,药物,药物养生疗法
摘要: Nanotechnology has shown great promise in health care offering numerous possibilities to significantly improve diagnosis of many dreadful diseases including Tuberculosis (TB). Nanomedicine has made the current drug regimen more effective against diseases particularly TB with attributes like sustained release, increased half life, higher drug concentrations at target sites, reduced toxicity and lesser side effects. However because of the severity of the disease, there is a strong urge to develop better approaches with some concomitant regimens using nano-particles to diagnose, treat and manage TB patients. The current review highlights some of the evolving strategies in the field of nanomedicine particularly drug delivery offering promising alternative for the current TB regimens. The study also emphasizes upon the need to design more effective nanocarriers which are highly specific, biocompatible and biodegradable as well.
Export Options
About this article
Cite this article as:
Rohit Sharma, Amanpreet Kaur, A. K. Sharma, Neeraj Dilbaghi, Anil K. Sharma , Nano-Based Anti-Tubercular Drug Delivery and Therapeutic Interventions in Tuberculosis, Current Drug Targets 2017; 18 (1) . https://dx.doi.org/10.2174/1389450116666150804110238
DOI https://dx.doi.org/10.2174/1389450116666150804110238 |
Print ISSN 1389-4501 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-5592 |
Call for Papers in Thematic Issues
Drug-Targeted Approach with Polymer Nanocomposites for Improved Therapeutics
Polymer nanocomposites have been recognized as an advanced and cutting-edge technique in drug targeting administration. These materials combine the unique features of nanoparticles with the adaptability of polymers to produce highly personalized drug administration devices. Integrating nanoparticles containing pharmaceuticals into a polymer matrix enables researchers to regulate the rates at ...read more
New drug therapy for eye diseases
Eyesight is one of the most critical senses, accounting for over 80% of our perceptions. Our quality of life might be significantly affected by eye disease, including glaucoma, diabetic retinopathy, dry eye, etc. Although the development of microinvasive ocular surgery reduces surgical complications and improves overall outcomes, medication therapy is ...read more
Therapeutic Chemical and RNA Design with Artificial Intelligence
Computer-Aided Drug Design (CADD) has emerged as a fundamental component of modern drug discovery. Molecular docking facilitates virtual screening on a large scale through structural simulations. However, traditional CADD approaches face significant limitations, as they can only screen known compounds from existing libraries. PubChem, as the most widely used chemical ...read more
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Analysis of Gene Logic Networks for Arabidopsis
Current Bioinformatics Enhanced Solubility and Increased Bioavailability with Engineered Nanocrystals
Current Drug Therapy Diversity and Functionality of Mycobacterial Mycolic Acids in Relation to Host-pathogen Interactions
Current Medicinal Chemistry Challenges and Opportunities for Bacterial Vaccine Development in the 21<sup>st</sup> Century
Current Pharmaceutical Biotechnology Review of the Phytochemistry and Biological Activity of Cissus incisa Leaves
Current Topics in Medicinal Chemistry A Review of Computational Identification of Protein Post-Translational Modifications
Mini-Reviews in Organic Chemistry HIV-1 Prophylactic Vaccine Trials in Thailand
Current HIV Research Biotechnological Approaches to the Production of Idiotypic Vaccines and Antiidiotypic Antibiotics
Current Pharmaceutical Biotechnology A Role of the 9-Aminoacridines and their Conjugates in a Life Science
Current Protein & Peptide Science Gender Disparity in Pediatric Diseases
Current Molecular Medicine Clinical Trials in Pakistan: Opportunities and Challenges
Applied Clinical Research, Clinical Trials and Regulatory Affairs The Use of Affinity Tags to Overcome Obstacles in Recombinant Protein Expression and Purification
Protein & Peptide Letters Coronavirus Disease (COVID-19): Features, Diagnosis, Treatments, and Impacts
Coronaviruses Understanding Recognition and Self-assembly in Biology using the Chemist´s Toolbox. Insight into Medicinal Chemistry
Current Topics in Medicinal Chemistry Cholestasis During Pregnancy: Aetiopathogenesis, Foetal-Maternal Repercussions and Pharmacological Treatments
Current Women`s Health Reviews Structure-based Discovery of Narirutin as a Shikimate kinase Inhibitor with Anti-tubercular Potency
Current Computer-Aided Drug Design Discovery of Potential Dual Inhibitors Against Lipases Rv0183 and Rv3802c for Tuberculosis Therapeutics
Letters in Drug Design & Discovery Submandibular Lymphadenitis in an Immunocompetent Female: Microbiological Confirmation is Need of the Hour
Infectious Disorders - Drug Targets Immune Response to Mycobacteria
Current Immunology Reviews (Discontinued) Identification of Active Phytochemical from Traditional Herbal Knowledge-base Targeting Pantothenate Synthetase for Anti-tuberculosis Therapy
Letters in Drug Design & Discovery