黄酮类，乳腺癌化学预防和化学治疗剂

Title:Flavonoids, Breast Cancer Chemopreventive and/or Chemotherapeutic Agents

Volume: 22 Issue: 30

Author(s): Chantal Beatrice Magne Nde, Stephane Zingue, Evelyn Winter, Tania Beatriz Creczynski-Pasa, Thomas Michel, Xavier Fernandez and Dieudonne Njamen and Colin Clyne

Affiliation:

关键词: 乳腺癌，化学预防剂，化学治疗剂，黄酮

摘要: Flavonoids are secondary metabolites abundantly present in commonly consumed fruits and vegetables. They possess diverse properties such as anti-inflammatory, anti-oxidant and anti-cancer. Epidemiologic studies suggest that an enrich flavonoids diet is linked to a decreased risk of breast cancer. These protective properties are due to the alteration of numerous signalling pathways involved in cancer-related phenomena such as inflammation and proliferation. Human clinical trials examining the effect of supplementation of some flavonoids on disease prevention have been conducted. There is no natural flavonoid that has been approved for the treatment of breast cancer. However, natural flavonoids served as lead compounds in the synthesis of cancer chemopreventive and/or therapeutic agents.

Cite this article as:

Chantal Beatrice Magne Nde, Stephane Zingue, Evelyn Winter, Tania Beatriz Creczynski-Pasa, Thomas Michel, Xavier Fernandez and Dieudonne Njamen and Colin Clyne , Flavonoids, Breast Cancer Chemopreventive and/or Chemotherapeutic Agents, Current Medicinal Chemistry 2015; 22 (30) . https://dx.doi.org/10.2174/0929867322666150729115321