摘要
光声成像(PAI)是新兴的用于研究小动物的可行的成像方法,有望在不远的将来走向临床。在这篇综述中,我们讨论了光声制导给药的前景。PAI有望用于药物释放的相关应用,主要关于监视药物作用和药物本身。PAI适用于病理和治疗反应的成像。PAI也能用于对各种累积的吸光造影剂或具有治疗能力的载体的直接监视。
关键词: 药物释放,影像引导治疗,光声,光热,治疗诊断学。
Current Drug Targets
Title:Opportunities for Photoacoustic-Guided Drug Delivery
Volume: 16 Issue: 6
Author(s): Jun Xia, Chulhong Kim and Jonathan F. Lovell
Affiliation:
关键词: 药物释放,影像引导治疗,光声,光热,治疗诊断学。
摘要: Photoacoustic imaging (PAI) is rapidly becoming established as a viable imaging modality for small animal research, with promise of near-future human clinical translation. In this review, we discuss emerging prospects for photoacoustic-guided drug delivery. PAI presents opportunities for applications related to drug delivery, mainly with respect to either monitoring drug effects or monitoring drugs themselves. PAI is well-suited for imaging disease pathology and treatment response. Alternatively, PAI can be used to directly monitor the accumulation of various light-absorbing contrast agents or carriers with theranostic properties.
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Cite this article as:
Jun Xia, Chulhong Kim and Jonathan F. Lovell , Opportunities for Photoacoustic-Guided Drug Delivery, Current Drug Targets 2015; 16 (6) . https://dx.doi.org/10.2174/1389450116666150707100328
DOI https://dx.doi.org/10.2174/1389450116666150707100328 |
Print ISSN 1389-4501 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-5592 |
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