摘要
免疫性血小板减少性紫癜（ITP）是最常见的自身免疫性疾病，是由抗体介导的血小板和巨核细胞-血小板生成受损产生的。ITP是一种排除性诊断。最近ITP的病理生理机制和治疗方法已开始出现。虽然类固醇和静脉注射免疫球蛋白（IVIg）仍然是主要的治疗策略，一组患者最终产生了耐药性，尤其是近十年已经有一些生物治疗方案，如利妥昔单抗。在这篇综述中，我们总结了ITP患者的治疗方案，主要集中在时间和生物制剂的潜在影响。
关键词: 自身免疫性疾病，生物治疗，免疫性血小板减少性紫癜，利妥昔单抗。
Call for Papers in Thematic Issues
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Chronic inflammation is a hallmark of numerous diseases, significantly impacting global health. Although chronic inflammation is a hot topic, not much has been written about approaches to its treatment. This thematic issue aims to showcase the latest advancements in chronic inflammation treatment and foster discussion on future directions in this ...read more
Cellular and Molecular Mechanisms of Non-Infectious Inflammatory Diseases: Focus on Clinical Implications
The Special Issue covers the results of the studies on cellular and molecular mechanisms of non-infectious inflammatory diseases, in particular, autoimmune rheumatic diseases, atherosclerotic cardiovascular disease and other age-related disorders such as type II diabetes, cancer, neurodegenerative disorders, etc. Review and research articles as well as methodology papers that summarize ...read more
Chalcogen-modified nucleic acid analogues
Chalcogen-modified nucleosides, nucleotides and oligonucleotides have been of great interest to scientific research for many years. The replacement of oxygen in the nucleobase, sugar or phosphate backbone by chalcogen atoms (sulfur, selenium, tellurium) gives these biomolecules unique properties resulting from their altered physical and chemical properties. The continuing interest in ...read more
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