摘要
微流体是一项引人注目的技术,从基因表达谱到细胞检测分析的应用表现了重要前景。由于其能够产生精确控制组分和窄尺寸分布的单微滴和多重微滴阵列的能力,最近微流体被应用到基因传递方面。本文就微流体基因传递的研究进展及进一步研究前景预测进行了综述。本综述旨在说明微流体在基因传递研究中的潜在作用及对提高基因治疗疗效的策略作新的阐述。
关键词: 微滴,基因传递,基因治疗,微流体,精密加工
Current Gene Therapy
Title:Microfluidic Methods for Non-Viral Gene Delivery
Volume: 15 Issue: 1
Author(s): Wing-Fu Lai
Affiliation:
关键词: 微滴,基因传递,基因治疗,微流体,精密加工
摘要: Microfluidics is a compelling technology that shows considerable promise in applications ranging from gene expression profiling to cell-based assays. Owing to its capacity to enable generation of single droplets and multiple droplet arrays with precisely controlled composition and a narrow size distribution, recently microfluidics has been exploited for delivery of genes. This article provides an overview of recent advances in microfluidic gene delivery, and speculates the prospects for further research. The objectives of this article are to illustrate the potential roles played by microfluidics in gene delivery research, and to shed new light on strategies to enhance the efficiency of gene therapy.
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Wing-Fu Lai , Microfluidic Methods for Non-Viral Gene Delivery, Current Gene Therapy 2015; 15 (1) . https://dx.doi.org/10.2174/1566523214666141114213915
DOI https://dx.doi.org/10.2174/1566523214666141114213915 |
Print ISSN 1566-5232 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5631 |
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