Abstract
Hyperactivity of sympathetic nervous system is one of the main mechanisms to play a role in the pathophysiology of hypertension. Its high prevalence and the low rates of adequate blood pressure control with pharmacological treatment brought interest to novel therapeutical strategies. Percutaneous renal sympathetic denervation emerged as an effective and safe alternative to reduce blood pressure in patients with resistant hypertension. Other potential indications to this procedure are heart failure, cases of insulin resistance, obesity, obstructive sleep apnea and cardiac arrhythmias.
Keywords: Blood pressure, hypertension, percutaneous ablation, renal denervation, resistant hypertension, sympathetic hyperactivity.
Current Hypertension Reviews
Title:Indications, Implications and Applications of Renal Denervation. Have we Discovered Something new?
Volume: 10 Issue: 1
Author(s): Cristiano de Oliveira Dietrich, Fabio Martins Nardo Botelho and Erlon Oliveira de Abreu-Silva
Affiliation:
Keywords: Blood pressure, hypertension, percutaneous ablation, renal denervation, resistant hypertension, sympathetic hyperactivity.
Abstract: Hyperactivity of sympathetic nervous system is one of the main mechanisms to play a role in the pathophysiology of hypertension. Its high prevalence and the low rates of adequate blood pressure control with pharmacological treatment brought interest to novel therapeutical strategies. Percutaneous renal sympathetic denervation emerged as an effective and safe alternative to reduce blood pressure in patients with resistant hypertension. Other potential indications to this procedure are heart failure, cases of insulin resistance, obesity, obstructive sleep apnea and cardiac arrhythmias.
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Cite this article as:
Dietrich de Oliveira Cristiano, Botelho Martins Nardo Fabio and Abreu-Silva Oliveira de Erlon, Indications, Implications and Applications of Renal Denervation. Have we Discovered Something new?, Current Hypertension Reviews 2014; 10 (1) . https://dx.doi.org/10.2174/157340211001141111145433
DOI https://dx.doi.org/10.2174/157340211001141111145433 |
Print ISSN 1573-4021 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6506 |
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