Abstract
Betulin, betulinic acid and their derived compounds are important pentacyclic lupane-type triterpenoids and exhibit diversified pharmacological activities like anti-HIV, antitumor, antimycotic, anti-inflammatory, antioxidant and immunomodulatory activities. Many new methods for the synthesis of potentially valuable betulin derived triterpenoids with potent bioactivity have been largely reported in the past few years. In this review, we will present the progress made on the synthesis of novel structural triterpenoids with excellent chemical or biological activity that have appeared from 2006 to 2012.
Keywords: Betulin, betulinic acid, heterocyclic derivatives, biological activity, synthetic method.
Call for Papers in Thematic Issues
Active Alkaloids: Structure, Mechanism of Action, Chemical Synthesis, and Biosynthesis
The scope of this topic encompasses the structure, mechanism of action, chemical synthesis, and biosynthesis of active alkaloids. Alkaloids, a class of nitrogen-containing organic compounds with alkaline properties, originate from a diverse array of sources. Many alkaloids exhibit significant biological activities and serve as key constituents in numerous medicinal plants. ...read more
Advancement in Petroleum Geochemistry
The scope of the thematic issue on advancements in petroleum geochemistry encompasses a broad range of cutting-edge research and technological innovations. This issue aims to highlight the latest developments in understanding the chemical and physical properties of petroleum and its geological formations. Key areas of focus include: Unconventional Resources: Exploring ...read more
Advancements in Synthesis of Bioactive Compounds
This thematic issue focuses on elucidating advanced synthetic strategies for bioactive compounds, with the primary objective of deepening understanding of the rational design and construction of target molecules. The exploration encompasses a diverse range of techniques, established name reactions, and cutting-edge synthetic methodologies. Specifically, the issue delves into the synthesis ...read more
Advances in Sustainable Synthesis and Applications of Cyclic Carbonates: From Green Chemistry to Advanced Materials
Cyclic carbonates have become a focus of attention because of their potential in sustainable chemistry, energy solutions, and advanced materials. Recent breakthroughs in their synthesis emphasize the use of CO₂ as a renewable feedstock, which is a step toward reducing carbon emissions. New catalytic processes, including both traditional metal catalysts ...read more
Related Books
2-Deoxy-D-Glucose: Chemistry and Biology
Chiral Ionic Liquids: Applications in Chemistry and Technology
Basics of Organic Chemistry: A Textbook for Undergraduate Students
Advances in Organic Synthesis
The Synthetic Methods, Structures, and Properties of the Ca-C σ Bond Organocalcium Containing Compounds
Advances in Organic Synthesis
Chemistry of Bipyrazoles: Synthesis and Applications
Advances in Organic Synthesis
Advanced Nanocatalysis for Organic Synthesis and Electroanalysis
Advances in Organic Synthesis
44