摘要
基于全球肺结核和耐药菌株的负担最近已经出现，对现有的治疗方法未做出回应，寻找新的救治方法来抵抗这种全球瘟疫患有艾滋病毒合并感染已成为当务之急。因此，寻找新药来抵抗致病源-结核杆菌（MTB），是一项长期的工作。该综述讨论了抗痨剂发病机理和抗结核药物研究的最先进水平，明确研究人员在该领域所面临的一些挑战和阐明可行性办法，尤其是在一些低收入国家。
关键词: 药物发现，耐药性，计算机筛选，肺结核
Call for Papers in Thematic Issues
Advances in Medicinal Chemistry: From Cancer to Chronic Diseases.
The broad spectrum of the issue will provide a comprehensive overview of emerging trends, novel therapeutic interventions, and translational insights that impact modern medicine. The primary focus will be diseases of global concern, including cancer, chronic pain, metabolic disorders, and autoimmune conditions, providing a broad overview of the advancements in ...read more
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Cellular and Molecular Mechanisms of Non-Infectious Inflammatory Diseases: Focus on Clinical Implications
The Special Issue covers the results of the studies on cellular and molecular mechanisms of non-infectious inflammatory diseases, in particular, autoimmune rheumatic diseases, atherosclerotic cardiovascular disease and other age-related disorders such as type II diabetes, cancer, neurodegenerative disorders, etc. Review and research articles as well as methodology papers that summarize ...read more
Chalcogen-modified nucleic acid analogues
Chalcogen-modified nucleosides, nucleotides and oligonucleotides have been of great interest to scientific research for many years. The replacement of oxygen in the nucleobase, sugar or phosphate backbone by chalcogen atoms (sulfur, selenium, tellurium) gives these biomolecules unique properties resulting from their altered physical and chemical properties. The continuing interest in ...read more
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