Abstract
The use of capillary electrophoresis with mass spectrometry (CE-MS) for metabolomic analysis has substantially increased in recent years. This hyphenated technique takes full advantage of the high separation efficiency of CE and the identification capability of MS, providing a powerful tool for rapid analysis and identification of metabolites in complex biological samples. This article focuses on an overview of some recent applications of CE-MS in metabolomics studies. We also discuss the techniques for the coupling of CE with MS and the potential of 2-D CE-MS for metabolomic analysis.
Keywords: CE-MS, 2-D CE, metabolomics.
Current Metabolomics
Title:Capillary Electrophoresis with Mass Spectrometry: Applications to Metabolomic Analysis
Volume: 1 Issue: 2
Author(s): Katie Yan, Jeffrey Brumbaugh, Jeremy Barrett, Sarah Jung and Shen Hu
Affiliation:
Keywords: CE-MS, 2-D CE, metabolomics.
Abstract: The use of capillary electrophoresis with mass spectrometry (CE-MS) for metabolomic analysis has substantially increased in recent years. This hyphenated technique takes full advantage of the high separation efficiency of CE and the identification capability of MS, providing a powerful tool for rapid analysis and identification of metabolites in complex biological samples. This article focuses on an overview of some recent applications of CE-MS in metabolomics studies. We also discuss the techniques for the coupling of CE with MS and the potential of 2-D CE-MS for metabolomic analysis.
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Cite this article as:
Yan Katie, Brumbaugh Jeffrey, Barrett Jeremy, Jung Sarah and Hu Shen, Capillary Electrophoresis with Mass Spectrometry: Applications to Metabolomic Analysis, Current Metabolomics 2013; 1 (2) . https://dx.doi.org/10.2174/2213235X11301020002
DOI https://dx.doi.org/10.2174/2213235X11301020002 |
Print ISSN 2213-235X |
Publisher Name Bentham Science Publisher |
Online ISSN 2213-2368 |
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