Abstract
The presence of DNA and RNA circulating in human plasma and serum is described. The possible sources of the DNA/RNA in blood, their ability to enter other cells and to express in the recipient cells are discussed and the relationship with metastases considered. The possible role(s) of the DNA/RNA in clinical diagnosis, in monitoring treatment and in prognosis are considered for diabetes and oncology.
Keywords: Circulating DNA/RNA, plasma/serum, diabetes, cancer, diagnosis, nucleic acid uptake/expression, recipient cells, human plasma, human blood, severe sepsis, clinical patients, systemic lupus erythematosus patients, cancer patients, tumour cell derived, cardiovascular disease
Infectious Disorders - Drug Targets
Title:Biology of Circulating Nucleic Acids and Possible Roles in Diagnosis and Treatment in Diabetes and Cancer
Volume: 12 Issue: 5
Author(s): Peter B. Gahan
Affiliation:
Keywords: Circulating DNA/RNA, plasma/serum, diabetes, cancer, diagnosis, nucleic acid uptake/expression, recipient cells, human plasma, human blood, severe sepsis, clinical patients, systemic lupus erythematosus patients, cancer patients, tumour cell derived, cardiovascular disease
Abstract: The presence of DNA and RNA circulating in human plasma and serum is described. The possible sources of the DNA/RNA in blood, their ability to enter other cells and to express in the recipient cells are discussed and the relationship with metastases considered. The possible role(s) of the DNA/RNA in clinical diagnosis, in monitoring treatment and in prognosis are considered for diabetes and oncology.
Export Options
About this article
Cite this article as:
B. Gahan Peter, Biology of Circulating Nucleic Acids and Possible Roles in Diagnosis and Treatment in Diabetes and Cancer, Infectious Disorders - Drug Targets 2012; 12 (5) . https://dx.doi.org/10.2174/187152612804142224
DOI https://dx.doi.org/10.2174/187152612804142224 |
Print ISSN 1871-5265 |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-3989 |
Call for Papers in Thematic Issues
New Frontiers in Infectious Disease Research: Small-Molecule Probes and Biomarker Identification
The biological relevance of small-molecule chemical probes targeting a disease model is crucial in the early stages of drug discovery. The integration of omics technologies such as genomics, proteomics, metabolomics, immunomic, and cellular levels has greatly enhanced the ability to identify novel biomarkers and understand the complex interactions between pathogens ...read more
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Virotherapy as An Approach Against Cancer Stem Cells
Current Gene Therapy Treatment Related Morbidity in Cervical Cancer
Current Women`s Health Reviews Postponing Motherhood: A Demographic and Contemporary Issue
Current Women`s Health Reviews Are Selenoproteins Important for the Cancer Protective Effects of Selenium?
Current Nutrition & Food Science The Medical Implications of Gastrointestinal Vagal Afferent Pathways in Nausea and Vomiting
Current Pharmaceutical Design Exploring Cancer Therapeutics with Natural Products from African Medicinal Plants, Part II: Alkaloids, Terpenoids and Flavonoids
Anti-Cancer Agents in Medicinal Chemistry Relationship Between Body Mass Index and Reproduction
Current Women`s Health Reviews Transmission Electron Microscopy as Key Technique for the Characterization of Telocytes
Current Stem Cell Research & Therapy Carcinoma of the Lower Uterine Segment (LUS): Clinicopathological Characteristics and Association with Lynch Syndrome
Current Genomics Circulating Nucleic Acids in Plasma and Serum: Roles in Diagnosis and Prognosis in Diabetes and Cancer
Infectious Disorders - Drug Targets Construction of an Anticancer Fusion Peptide (ACFP) Derived from Milk Proteins and an Assay of Anti-ovarian Cancer Cells in vitro
Anti-Cancer Agents in Medicinal Chemistry Anti-Invasive and Anti-Metastasis Strategies: New Roads, New Tools and New Hopes
Current Cancer Drug Targets Lysophospholipids: Synthesis and Biological Aspects
Current Organic Chemistry A Novel Method for the Analysis of Soluble Carbohydrates from Cistanche deserticola
Current Analytical Chemistry High Expression of MYL9 Indicates Poor Clinical Prognosis of Epithelial Ovarian Cancer
Recent Patents on Anti-Cancer Drug Discovery Current and Emerging Treatments for Metastatic Renal Cell Carcinoma
Current Cancer Drug Targets Biomolecules of Human Female Fertility - Potential Therapeutic Targets for Pharmaceutical Design
Current Pharmaceutical Design TRPC Channels and Their Splice Variants are Essential for Promoting Human Ovarian Cancer Cell Proliferation and Tumorigenesis
Current Cancer Drug Targets Liquid-based Cytology With HPV Triage of Low-grade Cytological Abnormalities Versus Conventional Cytology in Cervical Cancer Screening
Current Pharmaceutical Design Pumpkin Seeds (<i>Cucurbita spp</i>.) as a Nutraceutical Used In Various Lifestyle Disorders
The Natural Products Journal