Abstract
Pentoxifylline is methylxanthine derivative which is used in microcirculatory disorders as a vasoactive drug. Novel immunomodulatory properties of pentoxifylline have been reported including the down regulation of tumour necrosis factor-α synthesis and other inflammatory cytokines. Studies have shown that pentoxifylline might be efficacious in a wide spectrum of skin diseases. This article focuses on the use of pentoxifylline which is a safe and cheap drug in various dermatological disorders.
Keywords: Dermatology, disorder, pentoxifylline, treatment, tumor necrosis factor-α inhibitor, Anti-inflammatory, Venous ulcers, Behcet’s Disease, Recurrent Aphthous Stomatitis, Vasculopathy, Cutaneous Leishmaniasis
Inflammation & Allergy - Drug Targets (Discontinued)
Title:Pentoxifylline Use in Dermatology
Volume: 11 Issue: 6
Author(s): Seray Kulcu Cakmak, Atil Cakmak, Muzeyyen Gonul, Arzu Kilic and Ulker Gul
Affiliation:
Keywords: Dermatology, disorder, pentoxifylline, treatment, tumor necrosis factor-α inhibitor, Anti-inflammatory, Venous ulcers, Behcet’s Disease, Recurrent Aphthous Stomatitis, Vasculopathy, Cutaneous Leishmaniasis
Abstract: Pentoxifylline is methylxanthine derivative which is used in microcirculatory disorders as a vasoactive drug. Novel immunomodulatory properties of pentoxifylline have been reported including the down regulation of tumour necrosis factor-α synthesis and other inflammatory cytokines. Studies have shown that pentoxifylline might be efficacious in a wide spectrum of skin diseases. This article focuses on the use of pentoxifylline which is a safe and cheap drug in various dermatological disorders.
Export Options
About this article
Cite this article as:
Kulcu Cakmak Seray, Cakmak Atil, Gonul Muzeyyen, Kilic Arzu and Gul Ulker, Pentoxifylline Use in Dermatology, Inflammation & Allergy - Drug Targets (Discontinued) 2012; 11 (6) . https://dx.doi.org/10.2174/187152812803590028
DOI https://dx.doi.org/10.2174/187152812803590028 |
Print ISSN 1871-5281 |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-4055 |
Related Articles
-
Mechanisms of Thrombosis, Available Treatments and Management Challenges Presented by Thromboangiitis Obliterans
Current Medicinal Chemistry Vitiligo and Allergic Complications from Orthopaedic Joint Implants: The Role of Benzoyl Peroxide
Recent Patents on Inflammation & Allergy Drug Discovery Cardiovascular Complications of HIV Infection and Treatment
Cardiovascular & Hematological Agents in Medicinal Chemistry Resurgence of Herbal Antihypertensives in Management of Hypertension
Current Hypertension Reviews Flunarizine Dihydrochloride Nanoemulsion for Migraine Nasal Drug Delivery: Fabrication, Characterization and In Vitro Study
Drug Delivery Letters Exosomes: A Novel Therapeutic Paradigm for the Treatment of Depression
Current Drug Targets Use of Anti-Infective Drugs in Rheumatology
Anti-Infective Agents in Medicinal Chemistry Biosafety of Adenoviral Vectors
Current Gene Therapy Drug-Induced Aseptic Meningitis
Current Drug Targets - Immune, Endocrine & Metabolic Disorders A Case of Eosinophilic Granulomatosis with Polyangiitis Presenting with Mononeuritis Multiplex
Current Rheumatology Reviews (Section B: Integrated Function of Drug Transporters In Vivo) Drug Transport at the Blood-Brain Barrier and the Choroid Plexus
Current Drug Metabolism Chemotherapy Delivery Strategies to the Central Nervous System: neither Optional nor Superfluous
Current Cancer Drug Targets The Relationship between Inflammatory and Oxidative Stress Biomarkers, Atherosclerosis and Rheumatic Diseases
Current Pharmaceutical Design Drug Targeting of Estrogen Receptor Signaling in the Cardiovascular System: Preclinical and Clinical Studies
Current Medicinal Chemistry - Cardiovascular & Hematological Agents Reactive Oxygen Species in the Initiation of IL-4 Driven Autoimmunity as a Potential Therapeutic Target
Current Pharmaceutical Design A Case of Pulmonary Tuberculosis Mimicking as Diffuse Alveolar Hemorrhage: A Case Report
New Emirates Medical Journal Clinical and Forensic Signs Related to Cocaine Abuse
Current Drug Abuse Reviews New Therapeutic Aspects of Inflammatory Cardiomyopathy
Current Pharmaceutical Design Clozapine Induced Eosinophilia in a Case of Schizoaffective Disorder
Current Psychopharmacology Leptin in Non-Autoimmune Inflammation
Inflammation & Allergy - Drug Targets (Discontinued)