Optimizing Ventilation with the Open Lung Maneuver

Title: Optimizing Ventilation with the Open Lung Maneuver

Volume: 6 Issue: 4

Author(s): David Schwaiberger, Peter J. Papadakos and Burkhard Lachmann

Affiliation:

Keywords: Adult respiratory distress syndrome, ventilator associated lung injury, PEEP, open lung maneuver, mechanical ventilation, cytokines, ARDS, septicemia, prostacyclin, tumor necrosis factor-, interleukin-6, High frequency oscillation, hyperoxia, Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae, acidosis, MRUPL, bronchoscopy, ventilator

Abstract: This review addresses the current state of Lung Protective Ventilation and PEEP settings in critical ill patients, especially with Acute Respiratory Distress Syndrome (ARDS). Mechanisms of mediator and cytokine activation are described and results from clinical studies on mechanical ventilation are compared with results obtained in experimental studies. Furthermore, several ventilation strategies, particularly the Open Lung Maneuver, are discussed highlighting their role in the prevention of VALI. Finally, the Open Lung Maneuver is described through an example of an illustrative case.

Cite this article as:

Schwaiberger David, J. Papadakos Peter and Lachmann Burkhard, Optimizing Ventilation with the Open Lung Maneuver, Current Respiratory Medicine Reviews 2010; 6 (4) . https://dx.doi.org/10.2174/157339810793563686